Mannitol is a sugar alcohol commonly used in the pharmaceutical industry for various purposes. It is a white, crystalline powder with a sweet taste and is known for its ability to act as an osmotic diuretic. Mannitol finds applications in pharmaceuticals due to its unique properties, including solubility, stability, and low toxicity.
Browsing Category
Mannitol
New study: BENEO’s galenIQ™ proves suitable for powder feeding in continuous manufacturing
Press Release
New study: BENEO’s galenIQ™ proves suitable for powder feeding in continuous manufacturing
Mannheim (Germany), March 2023 – A recently published comparative scientific study demonstrates that BENEO’s agglomerated pharmaceutical excipient galenIQ™ is suitable for continuous…
Read More...
Read More...
The distribution of Drucker-Prager Cap model parameters for pharmaceutical materials
A model of the compaction process that has come into increasing use with the pharmaceutical industry is the Drucker-Prager Cap model (DPC). It has long been used in conjunction with the finite element methods to simulate the density and stress distributions in compacts. More recently the calibrated…
Read More...
Read More...
A ready-to-use dry powder formulation based on protamine nanocarriers for pulmonary drug delivery
The use of oral antibiotic therapy for the treatment of respiratory diseases such as tuberculosis has promoted the appearance of side effects as well as resistance to these treatments. The low solubility, high metabolism, and degradation of drugs such as rifabutin, have led to the use of combined…
Read More...
Read More...
Inhalable Microparticles Embedding Biocompatible Magnetic Iron-Doped Hydroxyapatite Nanoparticles
Recently, there has been increasing interest in developing biocompatible inhalable nanoparticle formulations, as they have enormous potential for treating and diagnosing lung disease. In this respect, here, we have studied superparamagnetic iron-doped calcium phosphate (in the form of…
Read More...
Read More...
Assessment of Tribo-charging and Continuous Feeding Performance of Direct Compression Grades of…
Tribo-charging is often a root cause of mass flow deviations and powder adhesion during continuous feeding. Thus, it may critically impact product quality. In this study, we characterized the volumetric (split- and pre-blend) feeding behavior and process-induced charge of two direct compression…
Read More...
Read More...
Oral lyophilizates obtained using aggressive drying conditions: Effect of excipients
Orodispersible drug formulations are a current trend in the pharmaceutical industry, mostly intended for pediatric and geriatric patients. Oral lyophilizates are solid forms, intended either to be placed in the mouth or to be dispersed (or dissolved) in water before administration. The correct…
Read More...
Read More...
Meeting Challenges of Pediatric Drug Delivery: The Potential of Orally Fast Disintegrating Tablets…
A majority of therapeutics are not available as suitable dosage forms for administration to pediatric patients. The first part of this review provides an overview of clinical and technological challenges and opportunities in the development of child-friendly dosage forms such as taste masking,…
Read More...
Read More...
Co-processed Hydroxypropyl Methylcellulose – Mannitol as a Directly Compressible Excipient for…
Introduction
Controlled release dosage forms deliver an effective dose of the active pharmaceutical ingredient over a prolonged duration, which is particularly advantageous to maintain a constant plasma drug concentration within the therapeutic window. This effectively overcomes the negative…
Read More...
Read More...
PEARLITOL® 200 GT Mannitol by Roquette
Speed. Precision. Patient-centricity.
Roquette´s PEARLITOL® 200 GT granulated mannitol is here to revolutionize direct compression. Realize the potential of novel drug formats with smaller, harder tablets produced at unprecedented speeds – without compromising on quality.
PEARLITOL® 200 GT…
Read More...
Read More...
Development and Optimization of Sildenafil Orodispersible Mini-Tablets (ODMTs) for Treatment of…
The availability of age-appropriate oral dosage forms for pediatric patients has remained a challenge. Orodispersible mini-tablets (ODMTs) are a promising delivery system for pediatric patients. The purpose of this work was the development and optimization of sildenafil ODMTs as a new dosage form…
Read More...
Read More...