Mannitol is a sugar alcohol commonly used in the pharmaceutical industry for various purposes. It is a white, crystalline powder with a sweet taste and is known for its ability to act as an osmotic diuretic. Mannitol finds applications in pharmaceuticals due to its unique properties, including solubility, stability, and low toxicity.
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Mannitol
Roquette Announces Commitment to Provide New Product Offerings
21. March 2017
New product offerings are low endotoxin, multi-compendial-grade materials for cell culture and biologic drug formulations. These products extend Roquette's commitment to helping customers save and sustain patients’ lives.
"As a long-time leader in…
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Physicochemical Characterization of Physical Mixture and Solid Dispersion of Diclofenac Potassium…
15. February 2017
Diclofenac potassium is an anti-inflammatory agent classified as a class II drug as per the biopharmaceutical classification system (BCS). The poor dissolution rate of water-insoluble drugs is still a major problem confronting the pharmaceutical industry. There are…
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Roquette Freres receives EXCiPACT certification
08. March 2016
Roquette Freres' plant in Lestrem, France, has earned EXCiPACT certification for Good Manufacturing Practice (GMP) from SGS France, one of EXCIPACT’s internationally-recognised certification bodies. The certificate covers the design, production and storage of…
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STEP Database Updated – 40 Excipients now!
25. February 2016
The STEP stands for Safety and Toxicity of Excipients for Paediatrics. It is a user-designed resource developed by European Paediatric Formulation Initiative (EuPFI) and United States Paediatric Formulation Initiative (USPFI) in collaboration for storage and…
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13C solid-state NMR analysis of the most common pharmaceutical excipients used in solid drug…
Excipients used in the solid drug formulations differ in their NMR relaxation and 13C cross-polarization (CP) kinetics parameters. Therefore, experimental parameters like contact time of cross-polarization and repetition time have a major impact on the registered solid state NMR spectra and in…
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Spray drying of nanoparticles to form fast dissolving glipizide – Article
Poor water solubility of pharmaceutical candidates creates a big barrier to development and clinical applications. In this study, glipizide as a poorly water soluble drug was precipitated as nanoparticles and processed by spray drying to produce fast dissolving powders. Nanosuspensions of…
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Announcement: STEP Database Updated – 29 Excipients now!
08. June 2015
Announcement: STEP Database Updated – 29 Excipients now!
The STEP stands for Safety and Toxicity of Excipients for Paediatrics. The Safety and Toxicity of Excipients for Paediatrics (STEP) Database is a user-designed resource developed by European Paediatric Formulation…
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Flow, packing and compaction properties of novel coprocessed multifunctional directly compressible…
Novel multifunctional excipients were prepared by coprocessing tapioca starch with mannitol using two methods viz; co-grinding and co-fusion. The flow, packing and compaction properties of the native and novel excipients were evaluated by using density, Hausner's ratio, angle of repose, the maximum…
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