Nanotechnology for excipients (or “nanotech”) is the use of matter on an atomic, molecular, and supramolecular scale for industrial purposes. The National Nanotechnology Initiative defined nanotechnology as the manipulation of matter with at least one dimension sized from 1 to 100 nanometers.
Pharma Excipients
Nanotechnology
Formulation Components’ Role in Shaping Continuous Nanocarrier Production through Impingement…
Presented at the 14th World Meeting on Pharmaceutics, Biopharmaceutics and Pharmaceutical (PBP) Technology, 18 - 21 March 2024, Vienna, Austria:
INTRODUCTION
The predominant approach for manufacturing nanocarriers on an industrial scale is batch production . Here, a specific quantity of raw…
Read More...
Read More...
Therapeutic Potential of Nanocarrier Mediated Delivery of Peptides for Wound Healing: Current…
Wound healing presents a complex physiological process that involves a sequence of events orchestrated by various cellular and molecular mechanisms. In recent years, there has been growing interest in leveraging nanomaterials and peptides to enhance wound healing outcomes. Nanocarriers offer unique…
Read More...
Read More...
Shifting from sustained to delayed drug delivery systems: Encapsulated mesoporous silica-chitosan…
The current study demonstrates a desired drug delivery-controlled system with a wide range of release parameters. It illustrates the feasibility of carriers in the systems for extended and short drug release. Herein, mesoporous silica nanoparticles (MSNs) coated with chitosan (Cs) grafted polylactic…
Read More...
Read More...
Implementation of an at-line nanoparticle size analyzer in a continuous nano-manufacturing line…
Presented at the 14th World Meeting on Pharmaceutics, Biopharmaceutics and Pharmaceutical (PBP) Technology, 18 - 21 March 2024, Vienna, Austria:
Introduction
A Process Analytical Technology (PAT) strategy for process and product monitoring is important to ensure adequate
product quality. This is…
Read More...
Read More...
Nanocarriers for Controlled Release and Target Delivery of Bioactive Compounds
See the new book, edited by Shaba Noore , Shivani Pathania , Pablo Fuciños , Colm P. O'Donnell , Brijesh K. Tiwari.
Description: This brief provides a comprehensive overview of nanocarriers used for nanoencapsulation of bioactive compounds. It includes the basis of encapsulation mechanism,…
Read More...
Read More...
Phospholipid Complex Formulation Technology for Improved Drug Delivery in Oncological Settings: a…
Addressing poor solubility and permeability issues associated with synthetic drugs and naturally occurring active compounds is crucial for improving bioavailability. This review explores the potential of phospholipid complex formulation technology to overcome these challenges. Phospholipids, as…
Read More...
Read More...
Is it advantageous to use quality by design (QbD) to develop nanoparticle-based dosage forms for…
Abstract
Parenteral administration is one of the most commonly used drug delivery routes for nanoparticle-based dosage forms, such as lipid-based and polymeric nanoparticles. For the treatment of various diseases, parenteral administration include intravenous, subcutaneous, and intramuscular…
Read More...
Read More...
Modification of microenvironmental pH of nanoparticles for enhanced solubility and oral…
This study aimed to develop a novel pH-modified nanoparticle with improved solubility and oral bioavailability of poorly water-soluble celecoxib by modifying the microenvironmental pH. After assessing the impact of hydrophilic polymers, surfactants and alkaline pH modifiers on the drug solubility,…
Read More...
Read More...
New Excipient For Oral Drug Delivery: CNC Derived From Sugarcane Bagasse-Derived Microcrystalline…
Abstract
Nanocrystalline cellulose (CNC) has emerged as a subject of researcher’s interest because of its diverse attributes encompassing biocompatibility, sustainability, a high aspect ratio, and an abundance of −OH groups suitable for modifications. Sugarcane bagasse microcrystalline cellulose…
Read More...
Read More...
Dissolution and antioxidant potential of apigenin self nanoemulsifying drug delivery system (SNEDDS)…
Abstract
Self-nanoemulsifying drug delivery systems (SNEDDS) have been used to improve the oral bioavailability of various drugs. In the current study, apigenin was developed as SNEDDS to solve its dissolution problem and enhance oral bioavailability and antioxidant potential. SNEDDS were…
Read More...
Read More...