The Importance of Amorphous Stability: Mesoporous Silica for Poor Glass Formers – Webinar
Manufacturing Strategies Webinar Series
The Importance of Amorphous Stability: Mesoporous Silica for Poor Glass Formers
This webinar will discuss the theory of amorphous stabilization followed by a discussion on mesoporous silica as an emerging approach for optimal stabilization of poor glass formers versus traditional polymeric ASDs.
In this webinar, you will learn:
- Why amorphous stability is a critical consideration in formulation development for poorly soluble compounds
- How amorphous stablity can be assessed using the glass forming ability
- Why poor glass former compounds can be challenging to formulate with traditional polymeric solid dispersions
- How mesoporous silica can stabilize poor glass formers via nanoconfinement and reduction in molecular mobility
Have also a look at Opportunities for Successful Stabilization of Poor Glass-Forming Drugs
Speaker:
Daniel Joseph Price,
Technical Product Manager- Solubility Enhancement
Daniel Joseph Price is technical product manager for our portfolio of solubility enhancement and sustained release excipients. Prior to his current role, Daniel was a Marie Curie Fellow also in our company with a focus on amorphous formulations. Specifically, Daniel’s expertise lies in mesoporous silica and thermodynamics of amorphous formulations. Daniel has a background in medicinal chemistry and formulation and is on track to receive his PhD from Goethe University Frankfurt in early 2020.
The life science business of Merck operates as MilliporeSigma in the U.S. and Canada.