Enhance API solubility. Achieve stable, high drug loads – with Parteck® MXP
Poor solubility of APIs is a critical challenge in drug development. One formulation technique to increase solubility and, consequently, improve bioavailability of drugs is hot melt extrusion (HME). With this technology, the API is dispersed into a polymer matrix to form an amorphous solid dispersion. The process is applicable to a broad range of poorly soluble APIs, making it suitable for various solid dosage formulations.
Parteck® MXP is a new polyvinyl alcohol-based excipient specifically designed for application in HME to increase solubility and allows for stable, high drug loads for a broad range of APIs. This animation provides an overview of the features and benefits Parteck® MXP offers in the HME process.
Benefits of Parteck® MXP:
- Enhanced solubility of APIs
- Stable, high drug load under various conditions
- High thermo-stability (above 200 °C) and a Broad API Application Range
- Variety of final oral dosage forms with immediate or sustained release kinetics using the same extrudates
- Ease of use thanks to optimized physical properties