Scalable electrospinning and -spraying solutions by Bioinicia
Your partner for advanced materials solutions for the pharma industry!
With more than a 100 years of cumulated experience, Bioinicia is the first company to have overcome the upscaling issues related to the electrospinning and electrospraying technology with a large-scale, pharma-grade GMP and ISO certified plant and a strong IP position around it.
Therefore, Bioinica has reached a unique positioning in the pharmaceutical industry, being the only company fully capable of developing and producing drugs with optimized performance (maximized potency and minimized side effects) of any given API.
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Bioinicia use…
- Non-woven mesh
- Multi-layered core-shell structures
- True encapsulation
- Nano-in-micro particles
- Sub-micronized particles and fibers
to create for you:
- Oral Disintegrating Tablets (ODT) and Oral Thin Films (OTF)
- Powder or granules for oral (tablets, capsules, sachets), parenteral, nasal, pulmonar, ophtalmic, vaginal & topical applications
- Patches for transdermal, mucosal, buccal & sublingual applications
What are the key features of Bioinicia and how can you benefit from them?
Versatile:
- Large-scale, continuous ISO & GMP-certified production for pharma
- Dry product in single-step
- Minimal moisture content and excellent processability of final product
- High reproduciblity & dose uniformity
- Use any solvent, excipient or API (even live cells) à solutions, suspensions, emulsions
- No stress applied to the API à highest product stability & quality
Maximize potency:
- Reach highest possible bioavailability à maximum reduction of drug strength while maintaining bioequivalence
- No degradation, but increased API stability
- Increase API dissolution
- Optimize administration route & release profile à e.g. faster onset, controlled release
- Narrow and controllable particle size distribution (50 nm – 10 µm)
- Highly controlled polymorphism/ crystallinity
Minify side effects:
- Related to gastroninternal interactions
- First-pass-effect
- Challenging release profile / therapeutic range
See the general principles of Electrospinning in the following video: