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COVID-19
Interactive dashboard of COVID-19 drugs in world pharmacopeias
Through the World Health Organization, ten international pharmacopeias—including USP—have collaborated to publish this interactive dashboard of active pharmaceutical ingredients and monographs for existing generic drugs being investigated as COVID-19 treatments. For any medicine to be safe and…
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How COVID-19 is Changing Research Culture
LONDON, UK (4 June 2020) – Life Science Newswire – Digital Science, a leading technology company serving emergent needs across the research sector, has today released a report highlighting the global research landscape trends and cultural changes in response to the COVID-19 pandemic.
The report…
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Application of Captisol® Technology to Enable the Formulation of Remdesivir in Treating COVID-19
James Pipkin, PhD, Vince Antle, PhD, and Rebecca Garcia-Fandiño, PhD, explain why more Captisol® than ever is required to meet Gilead’s bold goals of making remdesivir available to COVID-19 patients in the US and to hundreds of countries around the world. Check the full article on drug-dev.com…
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Can 3D printing of oral drugs help fight the current COVID-19 pandemic (and similar crisis in the…
The ongoing COVID-19 crisis has highlighted the importance of a robust drug supply chain which can be quickly and flexibly ramped up to produce life-saving drug treatments. 3D printing (3DP) of oral solid dosage forms (OSDF) could be a viable part of the emergency drug production response to…
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Tripartite Combination of Candidate Pandemic Mitigation Agents: Vitamin D, Quercetin, and Estradiol…
Genes required for SARS-CoV-2 entry into human cells, ACE2 and FURIN, were employed as baits to build genomic-guided molecular maps of upstream regulatory elements, their expression and functions in the human body, and pathophysiologically relevant cell types. Repressors and activators of the ACE2…
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Modified cyclodextrins as broad-spectrum antivirals
Viral infections kill millions of people and new antivirals are needed. Nontoxic drugs that irreversibly inhibit viruses (virucidal) are postulated to be ideal. Unfortunately, all virucidal molecules described to date are cytotoxic. We recently developed nontoxic, broad-spectrum virucidal gold…
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Combating Coronavirus: Key Role of Cyclodextrins in Treatment and Prevention
A new strain of coronavirus (2019-nCoV) started to emerge in late December 2019 from Wuhan, the capital of Hubei Province in central China, which is a city with a population of 11 million. The pneumonia- like illness, which has spread rapidly since first appearing in late December 2019, was declared…
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Combating Coronavirus: Key Role of Cyclodextrins in Treatment and Prevention
A new strain of coronavirus (2019-nCoV) started to emerge in late December 2019 from Wuhan, the capital of Hubei Province in central China, which is a city with a population of 11 million. The pneumonia- like illness, which has spread rapidly since first appearing in late December 2019, was declared…
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Vaccine Excipient Summary
Excipients Included in U.S. Vaccines, by Vaccine
In addition to weakened or killed disease antigens (viruses or bacteria), vaccines contain very small amounts of other ingredients – excipients.
Some excipients are added to a vaccine for a specific purpose. These include:…
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The race for coronavirus vaccines: a graphical guide
More than 90 vaccines are being developed against SARS-CoV-2 by research teams in companies and universities across the world. Researchers are trialling different technologies, some of which haven’t been used in a licensed vaccine before. At least six groups have already begun injecting formulations…
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