Dry Powder Inhalers (DPI)

This study describes the development and characterization of glucagon dry powder inhaler (DPI) formulation for pulmonary delivery. Lactose monohydrate, as a carrier, and L-leucine and magnesium stearate (MgSt) were used as dispersibility enhancers for this formulation. Methods: Using…
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Spray drying biologics and small-molecule drugs can increase their thermal stability relative to liquid dosage forms and allow for widespread distribution to developing countries without cold chain infrastructure. In this study, pullulan trehalose powder is spray dried for inhalation. The powder…
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Non-cystic fibrosis bronchiectasis (NCFB) is a chronic respiratory disease associated with the high morbidity and mortality. Long-term intermittent therapy by inhalable antibiotics has recently emerged as an effective approach for NCFB treatment. However, the effective delivery of antibiotics to the…
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Choice of carrier can have a significant impact on the capsule filling process as well as the performance of the DPI formulation. May 02, 2018 by Adeline Siew, PhD Pharmaceutical Technology, Volume 42, Issue 5, pg 30–33 The use of capsules loaded into a dry powder inhaler (DPI) to deliver drugs to…
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In this video you learn more about Armor Pharma's Lactose production and solutions offered. More on Armor Pharma
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Spray drying is increasingly becoming recognized as an efficient drying and formulation technique for pharmaceutical and biopharmaceutical processing. It offers significant economic and processing advantages compared to lyophilisation/freeze-drying techniques even though the optimisation of process…
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“How would you like your lactose?” is the first question Armor Pharma will ask you. Armor Pharma's commitment is to listen to customer’s needs, to strive to achieve the same goals and to provide suitable solutions. An especially design a customization tool now available on Armor Pharma's…
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The aerodynamic performance of a dry powder for inhalation depends on the formulation and the dry powder inhaler (DPI). In the case of capsule-based DPIs, the capsule also plays a role in the powder aerosolisation and the dispersion of the micronized drug during the inhalation. This study evaluated…
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The growing interest on polymeric delivery systems for pulmonary administration of drugs anticipates a more direct and efficient treatment of diseases such as tuberculosis (TB) that uses the pulmonary route as the natural route of infection. Polymeric microparticles or nano-in-microparticles offer…
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