Lipid Nanoarchitectonics for Natural Products Delivery in Cancer Therapy
Therapeutic applications of natural products have been noteworthy. A large sum of the population thrives on these products for countering multiple diseases and ailments. However, poor pharmacokinetic and pharmacodynamic profile of these molecules halted their progression as potential drug candidates. Other than that, low yield values are some of the added limiting factors of natural products as well.
Therefore, various measures have been taken to maximize the potential of these molecules in terms of their drug delivery perspectives. After a plenty of efforts, researchers could direct themselves towards nanoformulations as it was showing promising outcomes in various reported instances. Hence, we attempted to review the lipid-based nanoformulations/nanoarchitectonics, as is was found to be promising in terms of their drug delivery approach. Lipids are natural molecules that are biocompatible, biodegradable and they are an amicable medium for natural products delivery systems. Lipid nanoarchitectonics includes both vesicular and particulate based systems like liposomes, lipid micelles, solid lipid nanoparticles; nanostructured lipid carriers, etc.
Each of them has its own pros and cons, which makes them different from others. This chapter mainly covered the up-to-date information regarding various research work carried out on lipid nanoarchitectonics based natural product delivery for the treatment of cancer therapy.
Article Information: Author links open overlay panelChaudhari V.S., Hazam P.K., Banerjee S. (2020) Lipid Nanoarchitectonics for Natural Products Delivery in Cancer Therapy. In: Saneja A., Panda A., Lichtfouse E. (eds) Sustainable Agriculture Reviews 44. Sustainable Agriculture Reviews, vol 44. Springer, Cham.
Keywords: Natural products, Lipid Nanoformulations, Cancer therapy, Improved delivery, Lipids, nanotechnology