Chitosan-based spray-dried solid dispersions of apigenin in a 3D printable drug delivery system
Abstract
This study aims to develop chitosan-based apigenin (AGN) spray-dried solid dispersions (SDSDs) within a 3D pill. AGN SDSDs were prepared using 1:1 (AC1), 1:1.5 (AC2), and 1:2 (AC1) apigenin/chitosan weight ratios. The results of the process yield were found to be (87.5%, 94.2%, and 95.86%) and of drug assay were obtained as (95.2 ± …