Recent advances in polymer-based nanoformulations for enhancing oral drug delivery in diabetes
Diabetes is a long-term metabolic disorder caused by issues with insulin production or response in the body. This leads to high levels of glucose in the blood, which can cause other health problems. People with diabetes are advised to eat healthily and stay active to manage their blood sugar levels. However, if these lifestyle changes aren't…
Top 25 global pharma companies by market cap
26. March 2018 The completed analysis, performed by GlobalData, a data and analytics company, reveals a number of interesting insights. The pharma sector’s 2017 v 2016…
Hydrogels as intelligent materials: A brief review of synthesis, properties and applications
25. March 2018 Hydrogels are a unique class of three dimensional cross-linked polymeric networks that can hold a large fraction of aqueous solvents and biological fluids within…
Modeling the Effects of Material Properties on Tablet Compaction
25. March 2018 Modeling the Effects of Material Properties on Tablet Compaction: A building block for controlling both batch and continuous pharmaceutical manufacturing proces As…
Tablet fragmentation without a disintegrant: A novel design approach
25. March 2018 Fused deposition modelling (FDM) 3D printing has shown the most immediate potential for on-demand dose personalisation to suit particular patient's needs.…
IPEC and PDA team on excipient risk assessment guidance
23. March 2018
IPEC Federation and PDA will publish a technical report in 2019 to provide drugmakers guidelines on how to implement risk assessment challenges of excipient supply.
See our…
Soluplus – Regulatory Status update
22. March 2018
Soluplus® is an innovative excipient that enables new levels of solubility, and bioavailability for poorly soluble active ingredients but still not monographed in any pharmacopoeia. An update on…
Glatt CPS® Technology: Case study Poster @ PBP Worldmeeting in Granada
22. March 2018 The Glatt CPS® Technology (Complex Perfect Spheres) is a fluid bed rotor technology for producing spherical matrix pellets with a smooth surface and high…
Influence of polymer content on droplet size distributions in atomized spraying liquids
22. March 2018 To obtain a reproducible and specification conforming product quality it is mandatory to control the process parameters for granulation and layering or…
Orally Disintegrating Tablets Containing Melt Extruded Amorphous Solid Dispersion of Tacrolimus
21. March 2018 In order to improve the aqueous solubility and dissolution of Tacrolimus (TAC), amorphous solid dispersions of TAC were prepared by hot melt extrusion with…
Highlights of IPEC Europe Excipient Forum – Bordeaux 2018
20. March 2018
IPEC Europe's annual Excipient Forum took place on 1 February in Bordeaux, providing the usual high-quality insights into the
commercial, regulatory and scientific issues affecting both suppliers and…
Similar or Not? Dissolution Profiles of Different HPMC Capsules
19. March 2018 The effect of using different HPMC hard capsule shells on the in vitro dissolution profile of acetaminophen powder wasinvestigated. Use of HPMC capsule shells…
Starch film-coated microparticles for oral colon-specific drug delivery
19. March 2018 The aim of this study was to prepare and characterize a novel type of starch-coated microparticles (MPs) allowing site-specific delivery of bioactives to the…
News on Risk Assessment of Pharmaceutical Excipients
18. March 2018 This article describes a new, combined, quantitative method for assessing excipient risks that has been developed by the authors as one possible risk…
Pharmaceutical Excipients – Part 1
18. March 2018 This presentation will explain the definition of pharmaceutical excipients. Also, it shows the main regulation institutions and existing regulation. It shows…
In line monitoring of the powder flow behavior and drug content in a Fette 3090 feed frame
17. March 2018 Near infrared (NIR) spectroscopy was used to determine the drug concentration in 3% (w/w) acetaminophen blends within the complex flow regime of the tablet…
How to predict the in vivo sex-related influence of PEG 400 on oral drug absorption
16. March 2018 Sex-related differences in drug pharmacokinetics, especially regarding absorption and metabolism, are in part caused by a differential expression and/or…
Correlation of Solid Dosage Porosity and Tensile Strength with Acoustically Extracted Mechanical…
16. March 2018 Currently, the compressed tablet and its oral administration is the most popular drug delivery modality in medicine. The accurate porosity and tensile…
Quantification of Trace Levels of Active Oxygen in Pharmaceutical Excipients
16. March 2018 Pharmaceutical drug products contain various excipients in combination with the active pharmaceutical ingredient (API), and those excipients have the…
11th Swiss Pharma Science Day 2018 – “Cancer”
16. March 2018 This year's Swiss Pharma Science Day is focused on Cancer with the following presentations: «National Strategy Against Cancer» Dr. sc.nat.…
Impact of Metallic Stearates on Disproportionation of Hydrochloride Salts of Weak Bases in…
15. March 2018 Excipient-induced salt disproportionation (conversion from salt form to free form) in the solid state during storage or manufacturing is a severe formulation…
Evaluation of Pazopanib Phase Behavior Following pH-Induced Supersaturation
15. March 2018 Salts of weakly basic active pharmaceutical ingredients are widely used to improve aqueous solubility and/or dissolution rate. However, these compounds are…
Smallest Continuous Manufacturing – Formulation Expertise – Drug Delivery Solutions –…
15. March 2018
presented by Glatt @ 11th Worldmeeting on on Pharmaceutics, Biopharmaceutics and Pharmaceutical Technology -19 March to 22 March 2018 Granada, Spain
On the Glatt Booth N° 3 we will exhibit our…
Orogenta® ZOR – Controlled release matrix pharmaceutical dosage formulation
15. March 2018 The Orogenta® Technology enables to achieve zero-order release MUPS tablets coating of the embedded multiparticulates. Some key benefits are:…
Pharmaceutical spray freeze drying
14. March 2018 Pharmaceutical spray-freeze drying (SFD) includes a heterogeneous set of technologies with primary applications in apparent solubility enhancement, pulmonary…
The influence of lactose on the powder behavior and aerodynamic performance of bosentan…
13. March 2018 Abstract In this study, we prepared carrier-based formulations for dry powder inhalers by mixing bosentan microparticles with carrier, prepared in three…
Impact of Fast and Conservative Freeze-Drying on Product Quality of…
13. March 2018 Purpose Mannitol/sucrose formulations are employed to generate lyophilizates for biopharmaceuticals with an elegant cake appearance. The aim of this study…
Rational Design of Liquid Formulations of Proteins
13. March 2018 Abstract Twenty years ago, a number of eminent pharmaceutical scientists collaborated on an article describing a rational approach to developing stable…
Chitosan and Its Derivatives for Application in Mucoadhesive Drug Delivery Systems
13. March 2018 Mucoadhesive drug delivery systems are desirable as they can increase the residence time of drugs at the site of absorption/action, provide sustained drug…
Nutraceutical Excipients Market to Incur High Value Growth at 7.3% CAGR During 2017-2026
13. March 2018 For their nutritional and medicinal advantages, several bioactive compounds and ingredients are being used in the production of medical foods, functional…
Drug migration during drying of granules due to content non-uniformity in wet granulation
11. March 2018 Granulation is an integral step during pharmaceutical manufacturing of solid doses, which is usually followed by unit operations such as drying, milling,…
Design of buccal mucoadhesive tablets
10. March 2018 This article also includes a good overview of mucoadhesive tablets developed from 2012-2016 and also a compilation of the most used polymers…
3D PRINTING – 3D Printed Drugs Hold Great Potential for Personalized Medicine
09. March 2018
By Drug Development & Delivery
Issue: March 2018, Posted Date: 2/27/2018
This past year marked a milestone in the pharma industry when Aprecia Pharmaceuticals’ Spritam®…
Assessing Mucoadhesion in Polymer Gels
09. March 2018 The Effect of Method Type and Instrument Variables The process of mucoadhesion has been widely studied using a wide variety of methods, which are…
Sustained-release amorphous solid dispersions
09. March 2018 The use of amorphous solid dispersions (ASD) to overcome poor drug solubility has gained interest in the pharmaceutical industry over the past decade. ASDs…