Phospholipids for Pediatric Dosage Forms
Safe and Endogenous Compounds for Pharmaceutical Applications
Phospholipids are ubiquitous, endogenous, and nutritional compounds. For pharmaceutical applications, phospholipids are safe and versatile excipients for any administration route. This is demonstrated by their long-standing use in several innovative pediatric drug products and their…
Global Marketing Communications Specialist (with Digital Marketing experience)
21. February 2018
Tracking Code
1613
Job Description
The Marketing Communications Specialist reports to the Global Director of Marketing Communications and is responsible for all assigned marketing communications…
Estimating Number of PPQ Batches: Various Approaches
20. February 2018 Purpose The FDA’s process validation guidance 2011 has rightly resulted in discontinuing the “one size fits all” practice. The guidance aligns process…
Study of the die compaction of powders to high relative densities
20. February 2018 Abstract The mechanical behavior of powders during die compaction was investigated using the discrete element method (DEM), in which powders are modeled…
A Training on: Continuous Manufacturing (Direct Compaction) of Solid Dose Pharmaceutical Products
20. February 2018
As the pharmaceutical industry increasingly adopts continuous manufacturing technology, significant attention must be paid to process analytical technology (PAT), process integration, and process control.…
2nd Annual Advanced R&D Sourcing & Procurement in Pharma
20. February 2018 2nd Annual Advanced R&D Sourcing & Procurement in Pharma April 30 - May 1, 2018 in Boston, MA Harnessing Scientific Innovations and…
Effects of tablet formulation and film coating on the supersaturated dissolution behavior of…
19. February 2018 The effects of tablet preparation and subsequent film coating with amorphous solid dispersion (ASD) particles that were composed of a drug with poor water…
Fenofibrate Nanocrystals Embedded in Oral Strip-Films for Bioavailability Enhancement
19. February 2018 The aim of the present study was to make a fenofibrate (FNB) nanocrystal (NC) by wet media milling, characterizations and formulates into oral strip-films…
A Novel Approach for Dry Powder Coating of Pellets with Ethylcellulose
19. February 2018 The objective of this study was to assess the efficacy and the capability of a novel ethylcellulose-based dry-coating system to obtain prolonged and stable…
Polymers for solubility enhancement and enteric delivery – A Dow Webinar
19. February 2018 Solubility is the biggest challenge in the drug formulation processes. Register for the webinar Feb. 22, 11 AM EST as Kevin O'Donnell and I…
Fabricating 3D printed orally disintegrating printlets
18. February 2018 Abstract Selective laser sintering (SLS) is a three-dimensional printing (3DP) technology employed to manufacture plastic, metallic or ceramic objects.…
Excipient-drug pharmacokinetic interactions: Effect of disintegrants on efflux across excised pig…
17. February 2018 Abstract Pharmaceutical excipients were designed originally to be pharmacologically inert. However, certain excipients were found to have altering…
Quality control of freeze-dried oral formulations
16. February 2018 A common obstacle encountered in the early stages of drug development is the formulation of poorly water-soluble drugs (PWSDs). One effective approach to…
Engineering of Biomaterials for Drug Delivery Systems
16. February 2018 Here you find some abstracts of Engineering of "Biomaterials for Drug Delivery Systems - beyond Polyethylene Glycol". 1 – PEGylated…
Applications of Gels obtained on the Basis of Cellulose Derivatives
15. February 2018 Polymer physical gels have been used in numerous practical applications within food processing, chemical, cosmetics, pharmaceutical and agricultural…
Account Executive – Pharmaceutical Ingredient Sales
15. February 2018 Location: Anywhere in the Continental USA Compensation: $100-120K base salary plus 60% bonus potential and car Date: February 2018…
Amorphous Drug Solubility and Absorption Enhancement
15. February 2018 Just found this interesting chapter of the book "Amorphous Drugs" by Marzena Rams-Baron, Renata Jachowicz, Elena Boldyreva,…
FDA Recap of Warning Letters, Import Alerts and Non-Compliances 2017
14. January 2018 Data integrity continued to be a hot topic in the pharmaceutical industry through 2017. According to a recent analysis by GMP (good manufacturing practices)…
Solid lipid nanoparticles as an efficient drug delivery system of olmesartan medoxomil
14. February 2018 Abstract The aim of the current investigation was to develop solid lipid nanoparticles of olmesartan medoxomil using hot homogenization method to…
Polymer adhesion predictions for solid oral dosage forms
14. February 2018 Abstract Solid oral dosage forms (SODF) are drug vehicles commonly prescribed by physicists in primary and secondary cares, as they are the most…
Optimization of a semi-batch tablet coating process for a continuous manufacturing line by design of…
13. February 2018 Abstract The aim of the study was to optimize a tablet coating process for a continuous manufacturing line. High throughputs should be achieved while…
Hydrogel formulations for biologicals
13. February 2018 Hydrogels are, from a commercial perspective especially because of their ease of production, attractive sustained-release systems for high potent…
Evaluation of lubricants for optimal use in tablets
13. February 2018 Abstract As an essential formulation component for large-scale tablet manufacturing, the lubricant preserves tooling by reducing die-wall friction.…
Beyond PEGylation: Alternative surface-modification of nanoparticles with mucus-inert biomaterials
13. February 2018 Mucus is a highly hydrated viscoelastic gel present on various moist surfaces in our body including the eyes, nasal cavity, mouth, gastrointestinal,…
Linking API brittleness in high load formulations to the roller compaction process
12. February 2018 Abstract There is considerable interest in formulations with high active pharmaceutical ingredient (API) load, for reasons including lower patient…
Investigate the Effect of Solvents on Wet granulation of Microcrystalline Cellulose
12. February 2018
Introduction
Since decades, granulation is operational as a critical size enlargement process for powder agglomeration in tablet manufacturing. Dry granulation , melt granulation and wet…
Managing Risk in a Complex Excipient Supply Chain
12. February 2018 Regulations and industry guidelines focus on ensuring excipient safety by specifying risk assessments and shared responsibility. Feb 02, 2018 By…
Challenges and Opportunities in the Chinese Excipient Market
12. February 2018 With Transformation of the Chinese Pharmaceutical Industry Accelerated, Chinese Excipient Enterprises to Usher in New Challenges and Opportunities…
Dry-powder formulations of non-covalent protein complexes
10. February 2018
Abstract
Pulmonary delivery of protein therapeutics has considerable clinical potential for treating both local and systemic diseases. However, poor protein conformational stability, immunogenicity and…
Investigating effect of water of hydration on active pharmaceutical ingredients in a water-sensitive…
09. February 2018 Background Preparation of mini buccal tablets incorporating either of the Alzheimer’s drugs, rivastigmine tartrate or donepezil hydrochloride, were…
Thermal stabilization of biologics with photoresponsive hydrogels
09. February 2018 Modern medicine, biological research, and clinical diagnostics depend on the reli- able supply and storage of complex biomolecules. However, biomolecules…
Drug administration to pediatric patients: Evaluation of the nurses’ preparation habits in pediatric…
09. February 2018 In hospitals, the nursing staff is often confronted with the problem of the preparation and administration of drugs for their pediatric patients because of…
Continuous manufacturing – regulators have different approaches
08. February 2018 In the highly regulated pharmaceutical industry, manufacturers can’t help but wonder what regulatory authorities like the FDA think of emerging…
Challenge to optimize a powder/DPI combination for inhalation delivery of a bi-component generic…
08. February 2018 Development of bi-component generic orally inhaled product (OIP) delivered from dry powder inhaler (DPI) is challenging due to the necessity to demonstrate…
Improved HPMC films by incorporation of amylose-sodium palmitate
07. February 2018
Abstract
Polymer film blends of hydroxypropyl methylcellulose (HPMC) and amylose-sodium palmitate inclusion complexes (Na-Palm) were produced with no plasticizer, and were observed to have…