Microneedle patch casting using a micromachined carbon master for enhanced drug delivery
For successful treatment of diseases, sufficient therapeutics must be provided to the body. Microneedle applications in therapeutic delivery and analytics sampling are restricted because of various issues, including smaller area for drug loading and analytics sampling. To achieve sufficient drug loading and analytics sampling and improve drug…
Drug administration to pediatric patients: Evaluation of the nurses’ preparation habits in pediatric…
09. February 2018 In hospitals, the nursing staff is often confronted with the problem of the preparation and administration of drugs for their pediatric patients because of…
Continuous manufacturing – regulators have different approaches
08. February 2018 In the highly regulated pharmaceutical industry, manufacturers can’t help but wonder what regulatory authorities like the FDA think of emerging…
Challenge to optimize a powder/DPI combination for inhalation delivery of a bi-component generic…
08. February 2018 Development of bi-component generic orally inhaled product (OIP) delivered from dry powder inhaler (DPI) is challenging due to the necessity to demonstrate…
Improved HPMC films by incorporation of amylose-sodium palmitate
07. February 2018
Abstract
Polymer film blends of hydroxypropyl methylcellulose (HPMC) and amylose-sodium palmitate inclusion complexes (Na-Palm) were produced with no plasticizer, and were observed to have…
Chitosan Loaded into a Hydrogel Delivery System to Treat Vaginal Co-Infection
07. February 2018 Polymeric hydrogels are common dosage forms designed for the topical administration of antimicrobial drugs to treat vaginal infections. One of the major…
Continuous Manufacturing – get more insights!
07. February 2018
During the last years continuous manufacturing is one of the hot topcis in the pharmaceutical industry. Loads of publications, presentations and data is available. But have you ever seen such processes…
Excipient Samples – same same or different?
07. February 2018
What is your current way of organizing sample demands of your potential customers? Are you happy with the efforts put in and results achieved?
Has the sample procedure in the…
Inhalable Powder Formulation of 5-Fluorouracil
06. February 2018 Melanoma is the most aggressive and lethal type of skin cancer, with a poor prognosis because of the potential for metastatic spread. The aim was to…
Granulation & Tableting – A question mark?
06. February 2018
Granulation & Tableting - A question mark?
When was the last time you looked at the principles of granulation and tableting? Influence of the granulation process and parameters on the tableting?…
Predicting oral disintegrating tablet formulations by neural network techniques
06. February 2018 Oral Disintegrating Tablets (ODTs) is a novel dosage form that can be dissolved on the tongue within 3min or less especially for geriatric and pediatric…
Novel Excipients & New IPEC Guidelines @Making Pharmaceuticals Europe
06. February 2018
Novel Excipients & New IPEC Guidelines @Making Pharmaceuticals Europe
The conference program of Making Pharmaceuticals Europe also cover important excipient topics with expert presentations on:
New…
Learn more about drug formulation by using supercritical fluid technology
05. January 2018 Abstract Supercritical fluid (SCF) technology has been applied to drug product development over the last thirty years and drug particle generation using…
Content uniformity of quartered hydrocortisone tablets in comparison with mini-tablets for…
05. February 2018 Objectives Children requiring cortisol replacement therapy are often prescribed hydrocortisone doses of 2.5 mg, but as this is commercially…
World Drug Sales 2017-22 an Outlook
05. February 2018
An interesting Outlook from June 2017 by Evaluate Group. As the development of the drug market is important for the excipient market it can give also some indication some good indication where…
Oral solid self-nanoemulsifying drug delivery systems of candesartan citexetil
05. February 2018 Abstract Candesartan cilexetil is an ester prodrug antagonist to angiotensin II receptor type 1 (AT1) used in management of many cardiovascular…
Polymorphic and Covalent Transformations of Gabapentin in Binary Excipient Mixtures after…
02. February 2018 Purpose The purpose of the research described herein was to develop a kinetic model for quantifying the effects of conditional and compositional…
Microfluidic platforms to develop CNS-targeted polymeric nanoparticles for HIV therapy
02. February 2018 Abstract The human immunodeficiency virus (HIV) uses the brain as reservoir, which turns it as a promising target to fight this pathology. Nanoparticles…
Guideline on quality aspects included in the product information for vaccines for human use
02. February 2018 This guideline replaces 'Guideline on pharmaceutical aspects of the product information for human vaccines' (EMEA/CPMP/BWP/2758/02). This…
Pharma Excipients 2017 Articles – Available for Download
02. February 2018 During 2017 pharmaexcipients.com shared over 1.000 articles covering aspects of pharmaceutical excipients, formulation, regulatory, pharma market…
IPEC Europe – New Information Video
02. February 2018 During 2017, a project was initiated to transform the outcomes of many months of discussions into a new ‘look’!…
How to publish research – The pocket guide to good practice
02. February 2018
Just received the paper copy of this guide as a poster and pocket Version. It gives a great overview in a step-by-step approach to guide through the complex good practice Guidelines for writing and…
Inhalation: Co-Spray Dried Azithromycin Particles with L-Leucine
01. February 2018 Purpose Inhalation therapy is popular to treat lower respiratory tract infections. Azithromycin is effective against some bacteria that cause…
Director of Regulatory Affairs – Copenhagen, Denmark
01. February 2018 We are working with a joint venture created by one of the world’s largest designers and manufacturers of advanced drug delivery systems for the…
Managing acute pain in patients who report lactose intolerance
31. January 2018 Lactose intolerance is exceedingly common, reportedly affecting up to 70% of the world’s population, leading to both abdominal and systemic symptoms.…
Choosing a medication brand: Excipients, food intolerance and prescribing in older people
31. January 2018 Multiple brands of the same active ingredient may be available for the same strength, administration route and dose form. Generic brands needs to…
Formalizing a Risk Assessment for Excipients
31. January 2018
by: Frithjof Holtz, Merck KGaA, Darmstadt, Germany | Jan 29, 2018
Excipients serve a critical role in the production of final dosage forms for drug products and biologics. They facilitate the…
Excipient Requirements in Continuous Tablet Manufacturing
30. January 2018 Continuous Manufacturing Technology continues to gain importance in pharmaceutical manufacturing. Although traditional processes like direct compression,…
Ideal Cures is now hiring for its growing Sales, Business Development and International Marketing…
30. January 2018 We are on the look out for professionals with a B.Pharm/ M.Pharm/ MBA degree coupled with 3-15 years of relevant selling experience within the…
ExcipientFest Americas Summons Pharma Innovation and Risk Experts to Address Post Disaster…
30. January 2018
Arlington, VA - ExcipientFest will return to Puerto Rico to explore how crisis can be transformed into opportunity. The event will take place at the San Juan Marriott Stellaris Hotel on April…
Use of Polymers for Taste Masking Pediatric Drug Products
30. January 2018 Abstract Many drugs are bitter and overcoming this bitter taste is a major barrier in developing a successful product, especially for pediatric patients.…
FDA plans more restrictive policy for bulk drug compounding
29. January 2018
(Reuters) - The head of the U.S. Food and Drug Administration on Thursday said it is preparing a new, more restrictive policy targeting what drugs compounding pharmacies can produce that do not…
Selected Drug Delivery with Contact Lenses
29. January 2018 Abstract In this study, we evaluated contact lenses as drug delivery media and the effect of tear physiological pH on drug release behavior. Anionic or…
Nasal patches containing naphazoline for management of nasal impairments
28. February 2018 Abstract This study aimed to formulate a solid dosage form as decongestant for intranasal application. Nine formulations (A-K) based on gelatin and…
Improving Amorphous Solid Dispersions
26. January 2018
Abstract
The understanding of amorphous solid dispersions has grown significantly in the past decade. This is evident from the number of approved commercial amorphous solid dispersion products. While…