Microneedle patch casting using a micromachined carbon master for enhanced drug delivery
For successful treatment of diseases, sufficient therapeutics must be provided to the body. Microneedle applications in therapeutic delivery and analytics sampling are restricted because of various issues, including smaller area for drug loading and analytics sampling. To achieve sufficient drug loading and analytics sampling and improve drug…
Ophthalmic Drug Delivery Systems for Antibiotherapy
26. January 2018 The last fifty years, ophthalmic drug delivery research has made much progress, challenging scientists about the advantages and limitations of this drug…
Sales Forecast of FDA’s 2017 New Drug Approvals
26. January 2018 2017 was a landmark year for the pharmaceutical industries in the US and Europe, with a sharp increase in the number of new molecular entities (NMEs) being…
How real is your continuous manufacturing?
26. January 2018
During the last years continuous manufacturing is one of the hot topcis in the pharmaceutical industry. Loads of publications, presentations and data is available. But have you ever seen such processes live…
Cyclodextrins in Drug Formulation and Delivery
26. January 2018 Invitation to submit to this special issue Dear Colleagues Cyclodextrins (CDs) are cyclic oligosaccharides which are able to form…
Pharma dominiert Wachstum der Chemieindustrie
25. January 2018
Die positive Konjunktur in Europa schlägt auch auf die Chemie- und Pharmaindustrie durch: Ein sattes Umsatzplus und Produktionszuwachs haben in der Chemie zum höchsten Beschäftigungsstand seit 13 Jahren…
Containment – what is the current status?
25. January 2018
More and more of the new OSD drugs comprise of highly active components, where just milligrams of API are required for one daily medical dose. Thus, the pharmaceutical industry is facing increasing demand…
Bayer Animal Health: Research Scientist. Location: Shawnee, KS
25. January 2018 The primary responsibilities of this role, Bayer Animal Health Research Scientist, are to: Research, develop, validate, and…
Some easy Steps for a Smooth Preparation of Coating Dispersions
24. January 2018
Considering everything involved with advancing a drug from discovery to a marketed product, the preparation of the film coating may seem like a simple step; just mixing powder and water. Yet it is an…
Pharma’s getting left with the bill
24. January 2018
Did you know last year big Pharma companies Merck, Eli Lilly, Ranbaxy, Pfizer, Johnson & Johnson and Glaxo Smith Kline paid $13 Billion in penalties to different regulatory authorities directly related to…
Stabilization of Glucagon by Trehalose Glycopolymer Nanogels
23. January 2018
Abstract
Glucagon is a peptide hormone used for the treatment of hypoglycemia; however, its clinical potential is limited by its insolubility and instability in solution. Herein, the encapsulation,…
Formulation of Poloxamers for Drug Delivery
23. January 2018 Poloxamers, also known as Pluronics®, are block copolymers of poly(ethylene oxide) (PEO) and poly(propylene oxide) (PPO), which have an amphiphilic…
Learn more about Nanotherapeutics in oral and parenteral drug delivery
23. January 2018 Abstract Nanotechnology ushered the field of medicine in to a new era. Miniaturization, increased surface area, and the unique physicochemical properties…
Is this the end of lyophilization?
22. January 2018 Purdue research hub looks to make lyophilization obsolete Purdue University researchers and industry leaders are teaming up to transform the…
Synthetic glycopolymers as modulators of protein aggregation – Novel excipients to stabilize…
22. January 2018
Novel drug excipients are required to achieve stable formulations of protein drug candidates. Synthetic glycopolymers have been shown in some cases to improve protein formulation stability, although their…
A novel method for the production of core-shell microparticles by inverse gelation optimized with…
22. January 2018
Abstract
Numerous studies have been focused on hydrophobic compounds encapsulation as oils. In fact, oils can provide numerous health benefits as synergic ingredient combined with other…
pH-triggered surface charge-reversal nanoparticles alleviate experimental murine colitis via…
22. January 2018 In this study, we developed pH-triggered surface charge-reversal lipid nanoparticles (LNPs), loaded with budesonide, which could precisely deliver the drug…
Director Formulation Development Therapeutics – Bayer USA
22. January 2018 Your tasks and responsibilities The primary responsibilities of this role, Director Formulation Development Therapeutics, are to: …
3D extrusion printing of high drug loading immediate release paracetamol tablets
21. January 2018 Abstract The manufacture of immediate release high drug loading paracetamol oral tablets was achieved using an extrusion based 3D printer from a premixed…
Isomalt and its Diastereomer Mixtures as Stabilizing Excipients With Freeze-Dried Lactate…
21. January 2018 Abstract The purpose of this research was to study isomalt as a protein-stabilizing excipient with lactate dehydrogenase (LDH) during freeze-drying and…
Mathematically Modelling The Dissolution Of Solid Dispersions
20. January 2018 Abstract A solid dispersion is a dosage form in which an active ingredient (a drug) is mixed with at least one inert solid component. The purpose of the…
Characterisation of Pore Structures of Pharmaceutical Tablets
20. January 2018 Abstract Traditionally, the development of a new solid dosage form is formulation-driven and less focus is put on the design of a specific microstructure…
Effect of HPC molecular weight on granules and tablets prepared by two wet granulation methods
19. January 2018 January 2018 edition of Tablets & Capsules magazine features an article co-authored by Edmont Stoyanov, Berna Ehlig and Wade Tanev. In…
Quality Agreements and Templates for Pharmaceutical Excipients
19. January 2018 IPEC Webinar Tuesday, February 13, 2018 - 11:00am The concepts of what should be included in Quality Agreements have been explained in the…
Selected abstracts from Excipient Fest 2017
19. January 2018
The International Pharmaceutical Excipients Council (IPEC) is the global association of manufacturers and users of pharmaceutical Excipients. Each year, ExcipientFest Americas brings together a global…
Cannabinoid Disposition After Human Intraperitoneal Use
18. January 2018 Background Medicinal cannabis is prescribed under the provision of a controlled drug in the Australian Poisons Standard. However, multiple laws…
Drug-excipient interactions – ketoconazole-organic acid coamorphous systems
18. January 2018 The use of excipients other than polymers for enhancing the physical stability of amorphous active pharmaceutical ingredients (APIs) has largely been…
Gellan Gum/Pectin Beads for the Targeted Colonic Delivery of Resveratrol
18. January 2018 Abstract This work addresses the establishment and characterization of gellan gum:pectin (GG:P) biodegradable mucoadhesive beads intended for the…
Combat Counterfeiting and Protect your Brand
18. January 2018 The 7th Pharma Anti-Counterfeiting and Brand Protection Summit will be running again this year, March 26-28 in Philadelphia, PA. This event gathers key…
Join Oxford Global’s 4th Annual Formulation & Drug Delivery Congress
18. January 2018 Join Oxford Global’s 4th Annual Formulation & Drug Delivery Congress 8 – 9 May 2018 in London A new feature of the revamped 2018 agenda is…
Multiple Unit Pellet System (MUPS) based fast disintegrating sustained release tablets for…
17. January 2018 Abstract Controlled release dosage forms are essential in certain dosage regimens where release rate of drug impacts the effectiveness for therapy. In…
Pharmaceutical Quality by Design: A Practical Approach
A practical guide to Quality by Design for pharmaceutical product development
(This book also includes a chapter on the role of excipients in QbD written by Brian Carlin.)
Pharmaceutical Quality by Design: A Practical…
Top Pharmaceutical Market Research Trends in 2018
17. January 2018 Every year, InCrowd looks at what worked the previous year, and to the year ahead to see which emerging trends could prove sticky and are picking up…
Colorcon, Inc. Transforms the Sugar Coating Process with a New Opadry System
17. January 2018 HARLEYSVILLE, Pa.--(BUSINESS WIRE)-- Colorcon Inc. announces an exciting process development for sugar coated pharmaceutical tablets with the launch of…
Development of an oral once-weekly drug delivery system for HIV antiretroviral therapy
17. January 2018 The efficacy of antiretroviral therapy is significantly compromised by medication non-adherence. Long-acting enteral…