Highly soluble magnesium oxide for the food and supplement industry
What is magnesium oxide?
Magnesium oxide is a chemical compound with the formula MgO. Magnesium oxide is inorganic, consists of white crystals, and is normally insoluble in water. It has a high elemental magnesium content of approximately 58–60 % and can be used in food supplements where space is limited, such as tablets or capsules. It is also…
Development of an oral once-weekly drug delivery system for HIV antiretroviral therapy
17. January 2018 The efficacy of antiretroviral therapy is significantly compromised by medication non-adherence. Long-acting enteral…
Influence of lubrication and particle size distribution effects on tablet characteristics
16. January 2018 Abstract We adopt a Quality by Design (QbD) paradigm to better control the mechanical properties of tablets. To this end, the effect of particle size…
Learn more about Nasal adhesive patches against dry nasal syndrome
16. January 2018 Abstract This present study intended to provide nasal adhesive formulations for the topical treatment of dry nasal syndrome. Mucoadhesive films were…
Liquid-filled Formulations – a commentary
16. January 2018 Nowadays, the pharmaceutical industry is facing an increasing numbers of low solubility drug candidates and this issue hinders those compounds from…
Functional coatings of pH-responsive casein-based films
16. January 2018 Abstract Over the past few years, there has been increasing attention to the design of new drug delivery systems based on milk proteins due to their…
Versatile and on-demand biologics co-production in yeast
15. January 2018 Abstract Current limitations to on-demand drug manufacturing can be addressed by technologies that streamline manufacturing processes. Combining the…
Rheological Aspects of Polysaccharides
15. January 2018 Polysaccharides are natural polymers, or biopolymers with broad spectrum of applications due to their capability of modifying the solution properties by…
Mechanical and water barrier properties of hydroxypropyl methylcellulose films
15. January 2018 Abstract In line with the increasing demand for sustainable packaging materials, this contribution aimed to investigate the film-forming properties of…
Poly(methyl methacrylate) salt as film forming material to design orodispersible films
15. January 2018 Abstract This work aims to evaluate the possible use of a poly(sodium methacrylate, methyl methacrylate) (NaPMM2) plasticized by PEG400 in design…
Insulin Inclusion into a Tragacanth Hydrogel for oral drug delivery
11. January 2018 Abstract Nanoparticles or microparticles created by physical complexation between two polyelectrolytes may have a prospective use as an excipient for…
3D printed tablets with internal scaffold structure using ethyl cellulose to achieve sustained…
11. January 2018 Abstract The object of this study is to prepare and evaluate tablets with predesigned internal scaffold structure using 3D printing to achieve sustained…
Drug capsule may allow weekly HIV treatment
11. January 2018 Researchers have developed a capsule that can deliver a week’s worth of HIV drugs in a single dose. This advance could make it much easier for patients to…
Solvent-Induced Phase Separation in Amorphous Solid Dispersions
11. January 2018 This presentation @DDF Summit will cover the following topics: Amorphous solid dispersions Amorphous-amorphous phase separation Solvent…
Get insights on Technology Transfer by Design
11. January 2018 We just found this article from April 2017 and wonder if this is a real topic for the pharmaceutical industry and what is the situation actually. …
Influence of Low-Molecular-Weight Excipients on the Phase Behavior of PVPVA64 Amorphous Solid…
11. January 2018
Purpose
The oral bioavailability of poorly water-soluble active pharmaceutical ingredients (APIs) can be improved by the preparation of amorphous solid dispersions (ASDs) where the API is…
More about Biocompatibility of pharmaceutical excipients in liquid dosage forms
11. January 2018 Aqueous pharmaceutical solutions provide prosperous living conditions for microbiological agents. In order to eliminate these microbes, we use preservatives…
Gelatin Nano-coating for Inhibiting Surface Crystallization of Amorphous Drugs
11. January 2018 Purpose Inhibit the fast surface crystallization of amorphous drugs with gelatin nano-coatings. Methods The free surface of amorphous…
Chitosan-Based Zaleplon Nasal Microparticles
11. January 2018 The purpose of present research work was to develop mucoadhesive microparticles of Zaleplon nasal delivery with the aim to avoid hepatic first-pass…
Optimized tableting for extremely oxygen-sensitive probiotics using direct compression
10. January 2018
Abstract
Faecalibacterium prausnitzii was previously recognized for its intestinal anti-inflammatory activities and it has been shown less abundant in patients with chronic intestinal…
Role of plasticizer in membrane coated extended release oral drug delivery system
10. January 2018 Abstract Extended drug delivery offers numerous benefits compared to immediate release dosage form. Membrane coating of immediate release dosage form is…
Co association of mucus modulating agents and nanoparticles for mucosal drug delivery
10. January 2018 Abstract Nanoparticulate drug delivery systems (nDDS) offer a variety of options when it comes to routes of administration. One possible path is crossing…
A novel ethyl cellulose-coated sustained release multiple-unit system of tacrolimus
09. January 2018 Abstract A novel once-a-day sustained-release (SR) system of tacrolimus (FK506), a poorly water-soluble immunosuppressive agent, was designed employing…
Ketoprofen Nanosuspension by Solvent Evaporation Technique
09. January 2018 The effective surface area of drug particle is increased by a reduction in the particle size. Since dissolution takes place at the surface of the solute,…
Manufacturing the Future: a strategic approach to Product and Process development by Continuous…
09. January 2018 This presentation @DDF Summit will cover the following topics: J&J deployment strategy in continuous manufacturing CM in…
Alginate as a diphase solid dispersion carrier to enhance solubility
08. January 2018 Abstract The objective of this study was to explore the feasibility of using alginate as a promising diphase solid dispersion carrier to enhance…
Intestinal mucus penetration mechanism of core-shell noncomplex with insulin as model drug
07. January 2018 Abstract The objective of this study was to design intestinal mucus-penetrating core-shell nanocomplex by functionally mimicking the surface of virus,…
Learn more about carboxymethyl chitosan for the controlled release of propranolol
07. January 2018 Propranolol hydrochloride is a nonselective β-adrenergic drug and has been used as angina pectoris, antihypertensive, and that of many other cardiovascular…
Influence of Excipients on the Antimicrobial Activity of Tobramycin Against Pseudomonas aeruginosa…
06. January 2018 Purpose It is unknown if inactive pharmaceutical ingredients influence the activity of antibiotics they are co-formulated with. Recently it was found…
Outsourcing: 2017 in Review
06. January 2018 In a productive year, 2017 was filled with acquisitions, facility expansions, and new biopharma technology. Outsourcing in the…
2017 saw record approvals of generic drugs, novel drugs and devices by the USFDA
04. January 2018
The year gone by saw the highest number of generic drug approvals by the US Food and Drug Administration (FDA), along with the most ever novel drugs (46); the most ever novel devices, and the…
Discover calcium phosphates functionalities in direct compression formulations
04. January 2018
Calcium phosphates have been used in the pharmaceutical technology for many years. They have many physical and chemical properties that make them ideal candidates for the production of solid oral dosage…
Find out more on Mini-Tablets? Check this Review
03. January 2018 This review gives a nice overview on Multiple Unit Dosage Forms vs. Single Unit Dosage forms and a special focus on mini-tablets. Abstract…
Dry Powder Inhaler: Probing the Particulate Microstructure of the Aerodynamic Particle Size in…
03. January 2018 Abstract The in vitro aerosol performance of two combination dry powder inhaler (DPI) products, Foster® NEXThaler® and Seretide® Diskus® were…