Highly soluble magnesium oxide for the food and supplement industry
What is magnesium oxide?
Magnesium oxide is a chemical compound with the formula MgO. Magnesium oxide is inorganic, consists of white crystals, and is normally insoluble in water. It has a high elemental magnesium content of approximately 58–60 % and can be used in food supplements where space is limited, such as tablets or capsules. It is also…
Targeted Drug Delivery for Personalized Cure
14. December 2017 Human population bears a similarity to an extent of 99.9%, however mere 0.1% of variability also creates large differences in personal make-up owing to several…
On-Demand Controlled Drug Delivery
14. December 2017 Spatial and temporal control of drug delivery is of prime importance for establishing the therapeutic compliance of drugs for various diseases. Conventional…
Orodispersible Films for Compounding Pharmacies
14. December 2017 Orodispersible film can be defined as a solid pharmaceutical form intended for the delivery and rapid local or systemic release of active ingredients,…
Novel liposome-based and in situ gelling artificial tear formulation for dry eye disease treatment
14. December 2017
Purpose
Artificial tears are widely used in the treatment of dry eye disease, although current formulations do not closely resemble natural tears. The purpose of this study was the design and…
Dow Pharma Solutions – AAPS Posters
14. December 2017
Dow Pharma Solutions demonstrated its commitment to advancing the pharmaceutical sciences by exhibiting research findings in a range of posters at the 2017 AAPS show in San Diego, CA. Please find below…
The Next Great Serial: Pharmaceutical Security
14. December 2017
Experts estimate that 10% of medicines around the world may be counterfeit. Counterfeiting is growing due to the sophistication of counterfeiting methods and the increases in merchandise crossing borders.…
Xanthan gum as a rate-controlling polymer for the development of alcohol resistant matrix tablets…
13. December 2017 Abstract The vulnerability of controlled release formulations when co-ingested with alcohol represents a current major concern of regulatory agencies.…
Preparation and characterization of high drug-loaded microgranules: Particle sizing and mechanical…
13. December 2017 Abstract This study focuses on understanding the physicochemical principles for the preparation of high drug-loaded microgranules with a desired size…
Polyethylene Glycol (PEG) Exposure in Parenteral Therapies for the Pediatric Population
13. December 2017 INTRODUCTION Polyethylene glycol (PEG) is a chemically inert, amphiphilic polymer used as an excipient in many pharmaceuticals for decades, and as a…
Hot-melt extrusion technology in immediate-release abuse-deterrent formulations
13. December 2017
Objective: Hot-melt extrusion (HME) technology has been used for manufacturing extended-release abuse-deterrent formulations (ADFs) of opioid-type analgesics with improved tamper-resistant properties. Our…
Pediatric Drug Development – Visionary Promise Or Nightmare?
13. December 2017
SAPhS PharmaLunch
Basel, January 26, 2018
Klaus Rose, M.D., M.S., klausrose Consulting, Pediatric Drug Development & More
- Chronological age, physiology, and why children are not "therapeutic…
The impact of porosity on swelling kinetics of hydrophilic matrices
12. December 2017 The aim of the present investigation was to understand the swelling behaviour of HPMC and PEO-based matrices and to evaluate the impact of porosity on the…
Biocompatible inter polymer complex matrix tablets – an oral sustained release Metformin…
12. December 2017 Abstract Development of sustained release formulations of Metformin hydrochloride (Met) having low bioavailability and short half-life is one of the…
Co-Processed Excipient Guide Overview
12. December 2017 Webinar: Introducing the Co-processed Excipient Guide! Friday, December 15, 2017 - 11:00am to 12:00pm EST Featuring Joseph Zeleznik,…
Solid formulation of a supersaturable self-microemulsifying drug delivery system for valsartan
11. December 2017
Abstract
In order to improve the dissolution and oral bioavailability of valsartan (VST), and reduce the required volume for treatment, we previously formulated a supersaturable self-microemulsifying…
Significance of excipients to enhance the bioavailability of poorly water-soluble drugs in oral…
11. December 2017 Nowadays most of the drug substances are coming into the innovation pipeline with poor water solubility. Here, the influence of excipients will play a…
Preparation and comparison of tacrolimus-loaded solid dispersion and SMEDDS
11. December 2017 Abstract This study aimed to compare the dissolution and the intestinal absorption of tacrolimus in self-microemulsifying drug delivery system (SMEDDS)…
3D Printing in the Formulation of Multilayered Fast Dissolving Oral Films
10. December 2017 Fast dissolving oral films (FDFs) provide an alternative approach to increase consumer acceptance by advantage of rapid dissolution and administration without…
World Antibiotic Awareness Week, 13-19 November 2017
10. December 2017
Use antibiotics wisely to combat rising drug resistance
Excipients do not directly play a role in this topic but would like to raise your attention to this important topic.
During…
Simulation of hot-melt extrusion processes for amorphous solid dispersions using model-based melt…
09. December 2017 Simulation of HME processes is a valuable tool for increased process understanding and ease of scale-up. However, the experimental determination of all…
Functionality and performance evaluation of directly compressible co-processed excipients
09. December 2017 In the present work functional properties of new, co-processed excipients, Pharmaburst® 500, Parteck® ODT, Ludiflash® and Disintequik™ ODT, intended for…
Optimising the performance of oral cocrystal formulations via spray coating
08. December 2017 Engineering of pharmaceutical cocrystals is an advantageous alternative to salt formation for improving the aqueous solubility of hydrophobic drugs.…
The effects of mechanical dry coating microcrystalline cellulose with magnesium stearate
08. December 2017 Mechanofusion is a dry coating method that can be used to improve the flowability of cohesive powder by coating host particles with a lubricant, for…
Development of rectal self-emulsifying suspension of a moisture-labile water-soluble drug
08. December 2017 Self-emulsifying drug delivery systems, commonly used for oral delivery of poorly soluble compounds, were used to formulate water soluble but moisture…
Polysaccharides: Structure and Solubility
07. December 2017 Abstract Understanding the solubility of polysaccharides is extremely important for their food applications as most functions of polysaccharides…
Chitosan Nanoparticles as a Mucoadhesive Drug Delivery System for Ocular Administration
07. December 2017 Abstract Pharmaceutical approaches based on nanotechnologies and the development of eye drops composed of the mucoadhesive polymers chitosan and…
Anaphylactic reaction to galactose-derived oligosaccharides residues from lactose used as a drug…
06. December 2017 Abstract Inhaled steroids are currently the most widely used and recommended medicines for the management of persistent asthma because of their high…
Mixture design applied in compatibility studies of catechin and lipid compounds
06. December 2017 Abstract The aim of this work was to evaluate the compatibility of (+)-catechin (CA) and excipients commonly used to prepare micro and nanoemulsions…
Application of Slippery Film Coating for Easy Swallowing of Oral Dosage Forms
06. December 2017 Purpose The US FDA and EMA recently issued industry guidance focused on reducing risk associated with medication errors and improving patient…
Erythritol as sweetener?
06. December 2017 Abstract Erythritol is a naturally abundant sweetener gaining more and more importance especially within the food industry. It is widely used as…
Chronomodulated drug delivery system of Irbesartan – development with DoE
05. December 2017 Abstract The work is based on pulsatile principles to deliver a programmed dose of Irbesartan, an angiotensin-II receptor antagonist for chronotherapy…
Active Freeze Drying for production of nanocrystal-based powder
05. December 2017 Abstract Active Freeze Drying allows for producing lyophilised powders by progressive agitation of frozen blocks undergoing sublimation. One potential…
Evaluation of Coating Performance of INSTACOAT™ 4G in the Bectochem Perforated Pan
05. December 2017
Purpose
INSTACOAT™ 4G, a high solids, low viscosity formulation allows coating across a broad range of process parameters in any type of a coating equipment. It significantly reduces coating…
QR encoded smart oral dosage forms by inkjet printing
04. December 2017 Abstract The use of inkjet printing (IJP) technology enables the flexible manufacturing of personalized medicine with the doses tailored for each…