Highly soluble magnesium oxide for the food and supplement industry
What is magnesium oxide?
Magnesium oxide is a chemical compound with the formula MgO. Magnesium oxide is inorganic, consists of white crystals, and is normally insoluble in water. It has a high elemental magnesium content of approximately 58–60 % and can be used in food supplements where space is limited, such as tablets or capsules. It is also…
9th Global Drug Delivery & Formulation Summit
20. November 2017
9th Global Drug Delivery & Formulation Summit
12 – 14 March 2018 in Berlin
Where innovation meets industrial application
The growth of biopharma, patient compliance issues and ever…
Pharma Integrates Delivers a Strong Message to Industry
20. November 2017
With 372 attendees, 99 speakers, 31 sponsors and 14 channel partners in one place, Pharma Integrates 2017 was always going to be a busy — and noisy — affair, and it didn’t disappoint. In the…
IPEC updates guide to reflect changing pharma excipient landscape
20. November 2017
The International Pharmaceutical Excipient Council (IPEC) has updated its Quality Agreement guidelines to reflect changing regulatory expectations and global nature of supply chains.
More…
Rapidly-Disintegrating Laminar Extrudates – Age Appropriate Pediatric Formulation
18. November 2017
The aim of the present investigation is to produce rapidly disintegrating laminar extrudates for delivering ibuprofen in the mouth of paediatric patients. The laminar shape is particularly convenient for…
Comparative interfacial in vitro digestion of protein and polysaccharide oil/water films.
18. November 2017 The behaviour of proteins (β-lactoglobulin (βlg) and soy protein isolate (SPI)) and a surface active polysaccharide (hydroxypropylmethylcellulose, HPMC) o/w…
Novel rectal mucoadhesive hydrogels containing tolmetin sodium
18. November 2017 The objective of the present study was to develop rectal mucoadhesive hydrogels loaded with Tolmetin Sodium, a non-steroidal anti-inflammatory drug, for…
PAT technology for fluidbed processes
18. November 2017 by Innopharmatechnology & Glatt @ PMEC India 2017 Learn about the latest Process Analytical Technology (PAT) technical and application developments…
Cellulose Orodispersible Films of Donepezil
17. November 2017 Three versatile formulations of orodispersible films (ODFs) containing donepezil hydrochloride were prepared from cellulose derivatives by solvent casting…
Significance of Pharmaceutical Excipients
17. November 2017 In the designing and development of drug products from active drug(s), some of the important non-therapeutic substances are essentially included. These…
Excipients Market Growing But Novel Technologies Needed
16. October 2017 Excipients, once considered as far less important than the active pharmaceutical ingredient (API) in formulated medicines, today are receiving significantly…
Excipient Manufacturers: Practical Techniques for Conducting Risk Assessment
16. October 2017 December 7-8 2017 @IPEC-Americas Headquarters, Arlington More Information & Detailed Program Registration: Members…
Advantages of an excipients GMP certification
16. November 2017
Making a case for GMP certification of an excipient manufacturer should be a straightforward exercise since the benefits appear so clear cut and regulatory guidance in the EU underscores the value of certification.…
Formulation development of pediatric drug products: Safety qualification of excipients
16. November 2017 A public workshop entitled "Challenges and strategies to facilitate formulation development of pediatric drug products" focused on current status and gaps…
Excipients for Direct Compression – List available for download
15. November 2017 With the current hot topic of continuous manufacturing the topic of direct compression is also in the focus. There is a wide range of excipients for direct…
PVP VA64 as a novel release-modifier for sustained-release mini-matrices prepared via hot melt…
15. November 2017 The purpose of this study was to explore poly(vinylpyrrolidone-co-vinyl acetate) (PVP VA64) as a novel release-modifier to tailor the drug release from…
Amorphous Solid Dispersions and Nanocrystal Technologies for Poorly Water-Soluble Drug Delivery
15. November 2017 Abstract Poor water-solubility remains a typical property of drug candidates in pharmaceutical development pipelines today. Various processes have been…
Recent strategies in spray drying of poorly water-soluble drugs to enhance bioavailability
14. November 2017 Abstract Poorly water-soluble drugs are a significant and ongoing issue for the pharmaceutical industry. An overview of recent developments for the…
Evaluation of scale-up strategies for the batch synthesis of dense and hollow mesoporous silica…
13. November 2017
Abstract
Despite the wide application interest in mesoporous silica micro- and nano-particles and a number of synthesis routes reported in the literature, the question of chemical…
An organic solvent free, proliposomal formulation of Busulfan using Quality by Design approach
13. November 2017 Parenteral administration of Busulfan (BU) conquers the bioavailability and biovariability related issues of oral BU by maintaining the plasma drug…
New lipid-based formulation approaches and tools for characterization in hot-melt extrusion
13. November 2017 Amorphous solid dispersions (SDs) are considered as one of the most effective strategies for the formulation of poorly water-soluble compounds. The active…
Rising Interest in Taste-Masking Technologies
12. November 2017 Taste masking increases drug acceptability and medication adherence in pediatric, geriatric, and other special patient populations. Taste…
Vaccine Excipient & Media Summary
11. November 2017
Vaccine Excipient & Media Summary
Excipients Included in U.S. Vaccines, by Vaccine
The following table lists all components, other than antigens, shown in the manufacturers’ package insert…
Interfacial behaviour of pharmaceutical excipients
11. November 2017 Since drug release from dosage forms has importance for absorption from the gastrointestinal system, physicochemical characterisation of pharmaceutical…
Delivery by Design (DbD): An Approach for the Development of Efficacious Nanoparticle- and…
10. November 2017 Abstract The design and development of nanoparticle- and microparticle-based delivery systems for the encapsulation, protection, and controlled release…
Bucco Adhesive Systems: An alternative Strategy for Drug Delivery
10. November 2017 Mucoadhesive formulations are well known for the delivery of drugs via the mucosal membrane of oral (sublingual, buccal and gingival), rectum, nose, eyes,…
Melts of Octaacetyl Sucrose as Oral-Modified Release Dosage Forms for poorly soluble drugs
10. November 2017 The presented work describes the formulation and characterization of modified release glassy solid dosage forms (GSDFs) containing an amorphous nifedipine,…
Developing a quality by design approach to model tablet dissolution testing: an industrial case…
09. November 2017
This study applied the concept of Quality by Design (QbD) to tablet dissolution. Its goal was to propose a quality control strategy to model dissolution testing of solid oral dose products…
Drug Delivery Systems Synthetic Polymer-Based Nanoparticles: Intelligent Drug Delivery Systems
09. November 2017 Abstract One of the most promising strategies to improve the bioavailability of active pharmaceutical ingredients is based on the association of the…
Intestinal drug absorption and the solubility-permeability interplay
09. November 2017 Abstract The solubility-permeability interplay deals with the question: what is the concomitant effect on the drug‘s apparent permeability when…
Benefits of capsules as a dosage form
Capsules offer certain benefits over tablets for oral-solid dosage drugs, and several types of capsules are available
Oral-solid dosage (OSD) drugs can be formulated in tablet or capsule form. Some drugs are available only as…
Excipient exposure in very low birth weight preterm neonates
08. November 2017 OBJECTIVE: The excipients benzyl alcohol, propylene glycol and ethanol are present in medications used in the neonatal intensive care unit. Exposure to…
Local Tolerability to 5 Long-acting Drug Nanosuspensions with Different Stabilizing Excipients
08. November 2017 Abstract To investigate the effects of common nanosuspension-stabilizing excipients on the nature and temporal evolution of histopathological changes at…
Enteric coatings for colonic drug delivery: state of the art
08. November 2017 Colon delivery systems for oral administration have grown in popularity since the 1990s, primarily because of the increasing incidence of inflammatory…
Comparison of co-processed starches prepared by 3 different methods
08. November 2017
Abstract
Co-processing is currently of interest in the generation of high-functionality excipients for tablet formulation. In the present study, comparative analysis of the powder and…