Highly soluble magnesium oxide for the food and supplement industry
What is magnesium oxide?
Magnesium oxide is a chemical compound with the formula MgO. Magnesium oxide is inorganic, consists of white crystals, and is normally insoluble in water. It has a high elemental magnesium content of approximately 58–60 % and can be used in food supplements where space is limited, such as tablets or capsules. It is also…
Understanding die fill variation during mini-tablet
07. November 2017 Reproducibility of die fill during tablet production is critical to ensure consistent tablet drug content and mechanical attributes. In the production…
Co-processed Excipient Guide – First Version by IPEC
07. November 2017 General Considerations on excipients Excipients are a chemically diverse group of materials, and including all states of matter (solid, liquid, gas and…
Improvements of theobromine properties using solid dispersions prepared with new technologies
06. November 2017
Abstract
The aim of this study was to improve the pharmaceutical properties of theobromine (TB), particularly its flowability and dissolution rate, by preparing solid dispersions using different…
Powder flow analysis: A simple method to indicate the ideal amount of lactose fines in DPI…
06. November 2017 Abstract Many efforts have been made in the past to understand the function of lactose fines which are given as a ternary component to carrier-based dry…
Gelation Factors of Pectin for Development of a Dry Jelly, as a Novel Dosage Form
06. November 2017 Abstract Jellies for oral administration are dosage forms that contain water, as stipulated in the Japanese Pharmacopeia, and heat is generally applied…
A new lipid excipient, phosphorylated tocopherol mixture, TPM to enhance poorly water soluble CoQ10
05. November 2017 Phosphorylated tocopherols are a new class of lipid excipients that have demonstrated potential in pharmaceutical applications. Their ability to solubilise…
Design space mapping by amorphous ionic liquid strategies
05. November 2017 Poor water solubility of drugs fuels complex formulations and jeopardizes patient access to medication. Simplifying these complexities we systematically…
Characterization of Complex Excipients and Formulations
04. November 2017 Presentation of Yan Wang Division of Therapeutic Performance Office of Research and Standards Office of Generic Drugs - FDA…
3D Printing of Pharmaceuticals
03. November 2017 In the new era of medicine, 3D printing technique in pharmaceutical manufacturing has already yielded success. For example, Aprecia®, an FDA-approved…
The role of excipients in neglected tropical diseases
03. November 2017 Leishmaniasis is a neglected tropical disease responsible for the ninth largest disease burden in the world threatening 350 million people mostly in…
A Semi-Continuous Operations Model For Generic Solid-Dose Manufacturing
03. November 2017 The estimated timeline for a drug product from discovery to market is 10 to 15 years. However, less than 12 percent of drug candidates that enter clinical…
Kaolinite in pharmaceutics and biomedicine
03. November 2017 Kaolinite Al2Si2O5(OH)4 is an abundant and inexpensive geomaterial regarded as one of the most common clay minerals in the earth's crust and the most…
Melt-Extruded Shellac Carrier for the Targeted Delivery of Probiotics to the Colon
03. November 2017
Hot melt extrusion (HME) is considered an efficient technique in developing solid molecular dispersions, and has been demonstrated to provide sustained, modified and targeted drug delivery…
Hydrogels and Their Combination with Liposomes, Niosomes, or Transfersomes
02. November 2017 Polymeric networks that retain and absorb substantial amount of water or biological fluids and resemble as a biological tissue are defined as hydrogels. On the…
Pre-activated α-cyclodextrin as a mucoadhesive excipient for intra-vesical drug delivery
02. November 2017 The study was designed to synthesize and characterize pre-activated α-cyclodextrin (α-CD) derivatives as mucus adhering excipients for…
Impact of the US FDA Biopharmaceutics Classification System (BCS) Guidance on Drug Development
01. November 2017 The FDA guidance on application of the Biopharmaceutics Classification System (BCS) for waiver of in-vivo bioequivalence (BE) studies was issued in August…
Define influence of polymer on buccal tablet characteristics by factorial design
01. November 2017 A two factor three level factorial design was used to investigate the effects of carbopol and cationic hydrophilic polymers which have a common use in…
Pharmaceutical nanocarriers for the formulation of poorly soluble drug
01. November 2017 Poor solubility of drugs has always been an issue for formulation scientists thus the search for novel excipients or techniques is an ever-important field…
Emulgels: Application Potential in Drug Delivery
01. November 2017 Emulgels have been extensively employed as emerging drug delivery systems for the administration of lipophilic or hydrophobic drugs, particularly as a boon…
Evaluation of two novel plant gums for bioadhesive microsphere and sustained-release
01. November 2017 Background. The biological half life of metformin requires multiple doses which are associated with poor patient compliance. This justifies the need for a…
Dendritic core-multishell nanocarriers for efficient dermal drug delivery
31. October 2017 Drug loaded dendritic core-multishell (CMS) nanocarriers are of especial interest for the treatment of skin diseases, owing to their striking dermal…
Small molecule delivery to solid tumors with chitosan-coated PLGA particles
31. October 2017 For polymeric nanoparticles (NPs) to deliver more drugs to tumors than free drug solution, it is critical that the NPs establish interactions with tumor…
Orodispersible tablets containing taste-masked solid lipid pellets with metformin hydrochloride
31. October 2017 Compaction of multiparticulates into tablets, particularly into orodispersible tablets (ODTs), is challenging. The compression of pellets, made by solid…
Omeprazole MUPS®: An advanced formulation solution
Omeprazole is a pro-drug that accumulates in the acid space of the parietal cell where it is transformed to the active state. However the drug has several characteristics which determine its access to this site of action. Omeprazole is a…
Drug–excipient interactions in the solid state
30. October 2017 Understanding properties and mechanisms that govern drug degradation in the solid state is of high importance to ensure drug stability and safety of solid…
Nebulized coenzyme Q10 nanosuspensions: A pulmonary antioxidant therapy
30. October 2017 Coenzyme Q10 (CoQ10) is an antioxidant substance indicated as a dietary supplement which has been proposed as…
FDM 3D printing of modified drug-delivery systems using hot melt extrusion
30. October 2017 The production process of 3D-printed drugs offers unique advantages such as the possibility of individualizing the drug therapy and easily associating…
Different effects of silica added internal or external on in vitro dissolution
30. October 2017 The purpose of this work was to investigate the effect on the dissolution behavior when silica was added in different ways. The solid dispersion was…
Managing Your FDA Inspection: Before, During and After
30. October 2017
Training Date: April 26th & 27th, 2018
Location: Courtyard Seattle Sea-Tac Area 16038 West Valley Highway Tukwila Washington 98188 USA
Length: 2 Days
Price:
Price: $1,295.00 (Seminar Fee for One…
Advantages of Jelly over Liquid Formulations for Pediatrics
29. October 2017 Abstract Jellies for oral administration are non-flowable gelatinous preparations having a certain shape and size. This dosage form is being explored for…
Multiple Unit Particle Systems (MUPS) – a drug delivery strategy
29. October 2017 In oral drug delivery modified release dosage forms (MRD) plays an important role in regulating the drug delivery to improve the quality of therapy. One…
Pullulan based oral thin film formulation of zolmitriptan
28. October 2017
Thegoal of study was to formulate and characterize pullulan based oral thin film (OTF) of zolmitriptan by solvent casting method. Based on preliminary trials, glass, PEG 400 and sucralose were selectedas…
Formulation of 3D Printed Tablet for Rapid Drug Release
27. October 2017 The primary aim of this study was to identify pharmaceutically acceptable amorphous polymers for producing 3D printed tablets of a model drug, haloperidol,…
Functionalization of Tamarind Gum for Drug Delivery
27. October 2017 Tamarind gum is a plant polysaccharide extracted from seed endosperm of the plant, Tamarindus indica Linn. (Family: Fabaceae). It is a neutral, nonionic,…