Highly soluble magnesium oxide for the food and supplement industry
What is magnesium oxide?
Magnesium oxide is a chemical compound with the formula MgO. Magnesium oxide is inorganic, consists of white crystals, and is normally insoluble in water. It has a high elemental magnesium content of approximately 58–60 % and can be used in food supplements where space is limited, such as tablets or capsules. It is also…
Increase in Dissolution Rate of Simvastatin by Amorphous Solid Dispersion
25. September 2017 ABSTRACT The objective of the present study was to prepare amorphous solid dispersion system simvastatin – hydroxypropylmethylcellulose (HPMC) to…
The pursuit of user-friendly medicines: Older people in the hot seat
25. September 2017 Objectives of this thesis The objectives of this thesis are to provide insight in the problems that older people experience with the daily use of…
Stability-Enhanced Ternary Solid Dispersions with HPMC and Soluplus
24. September 2017
Abstract
The aim of this study was to evaluate a novel combination of hydroxypropyl methylcellulose phthalate (HPMCP-HP-50) and Soluplus®polymers for enhanced physicochemical stability and solubility of…
Characterization of a Thermoresponsive Water- Soluble Polymer
24. September 2017 Abstract Thermoresponsive polymers are a class of smart materials that exhibit change in their…
Preparation of Transdermal Films of Nifedipine
24. September 2017
Objective: The aim of present study was to prepare and evaluate the transdermal lms (TFs) of Nifedipine (NFDP).
Methods: The TFs were prepared by solvent evaporation technique and twelve…
Automating Excipient Selection
24. September 2017
In the interest of saving time and reducing costs, drug developers are automating the screening process when selecting excipients for solubility.
Evaluating the pharmacological,…
Oral Time-Controlled Release Etodolac Pellets
21. September 2017 Abstract The objective of this study was to prepare time-controlled release etodolac pellets to facilitate drug administration according to the body’s…
Dissolution of Gelatin Capsules: Evidence and Confirmation of Cross-Linking
21. September 2017 ABSTRACT Cross-linking is a common problem in the dissolution of gelatin capsules. Cross-linking is characterized by a bridge across the peptide…
Adhesive Dermally Applied Microarray (ADAM) For Acute Treatments
21. September 2017 Free Webinar Thu, Jan 25, 2018 6:00 PM - 7:00 PM CET Information & Registration…
In vivo evaluation of pH and time-dependent polymers as coating agent for colonic delivery using…
20. September 2017 Abstract The objective of this study was to evaluate the combination of pH-dependent and time-dependent polymers on drug release in order to optimize…
A comprehensive screening platform for aerosolizable protein formulations for intranasal and…
20. September 2017
Aerosolized administration of biopharmaceuticals to the airways is a promising route for nasal and pulmonary drug delivery, but − in contrast to small molecules − little is known about the effects of…
Formulation & Drug Delivery USA Congress
20. September 2017 Formulation & Drug Delivery USA Congress Formulation & Drug Delivery USA Congress 2018 Get more Information & Agenda
A study of inert and functionalized spheres coated with solid dispersions
19. September 2017 A comparative study on the performance of inert and functionalized spheres coated with solid dispersions made of two structurally related antifungal drugs…
Development of nicotine loaded chitosan nanoparticles for lung delivery
18. September 2017 Abstract of Thesis Cigarette smoking has become one of the leading causes of preventable deaths all over the world, causing a serious threat to human…
Multi-particulate Drug Delivery Systems of Methylphenidate Hydrochloride
18. September 2017 Introduction: The objective of the present investigation was to develop a multiparticulate modified release system of methylphenidate hydrochloride (HCl)…
StarCap 1500® Co-Processed Starch Excipient
17. September 2017
StarCap 1500 is a unique co-processed mixture of globally accepted excipients, corn starch and pregelatinized starch, designed for use in capsules and tablets.
StarCap 1500 is an inert free-flowing…
Excipient Stability in Oral Solid Dosage Forms
16. September 2017 The choice of excipients constitutes a major part of preformulation and formulation studies during the preparation of pharmaceutical dosage forms. The…
Control of the Dissolution Profile of Paracetamol from Carbomer Matrix Tablets
16. September 2017 Results of experiments on prolonged release of paracetamol from polymer matrix tablets with cross-linked poly(acrylic acid) Carbopol®Ultrez 21 as the…
Mechanical Particle Coating Using Polymethacrylate Nanoparticle Agglomerates for the Preparation of…
16. September 2017 Abstract We aimed to understand the factors controlling mechanical particle coating using polymethacrylate. The relationship between coating…
Factor analysis in optimization of formulation of high content uniformity tablets containing low…
16. September 2017 Abstract Warfarin is intensively discussed drug with narrow therapeutic range. There have been cases of bleeding attributed to varying content or…
Harmonization of excipient USP-NF standards
15. September 2017 Excipients are critical for a drug to be effective. However, they can also cause great harm if their quality if poor. By creating standards for…
PELLETS AND MICROPELLETS FOR ORAL MULTIPARTICULATE DOSAGE FORMS
15. September 2017
More and more pharmaceutical products are reaching the market as multiparticulate dosage forms, mainly as pellets. The healthcare sector also frequently selects pellets as the optimal marketable form of…
Extended-release solid dispersion granules of tacrolimus: release mechanism and oral bioavailability
14. September 2017 Objectives We aimed to prepare a once-daily modified-release oral formulation of tacrolimus by utilizing an extended-release granules (ERG). Methods…
Enhancement of dissolution behavior of antiarthritic drug leflunomide using solid dispersion methods
14. September 2017 Abstract Novel pharmaceutical formulations of antiarthritic drug leflunomide (LEF) with polyvinylpyrrolidone (PVP), polyethylene glycol (PEG) and…
Course on powder flow by Granutools
14. September 2017 November 9th, 2017 in Belgium Come and discuss your hottest powder flow characterization questions. Ask us the detailed program or…
Infacort®: a PUMA success story
14. September 2017
Prof Martin Whitaker (The University of Sheffield) will present at the 9th conference of the European Paediatric Formulation Initiative (EuPFI) in Warsaw (Poland) on Thursday 21st September 2017 at 12:25.…
Development of Nifedipine Timed-release Spansule Dosage form by Extrusion-Spheronization Technology
14. September 2017 Aims: Sustained-release formulations have been widely developed to improve the therapeutic performance of drugs, in particular, to increase…
Formulation and Evaluation of Colon Targeted Compression Coated Tablet of Mesalamine and…
14. September 2017 Introduction: The purpose of this study was to formulate compression coated tablets of mesalamine and prednisolone for colon specific delivery and…
Tablets & Capsules September Issue
14. September 2017 Tablets & Capsules September Issue Topics A novel taste-modulating excipient based on the use of solid-state myceliation…
Fabrication of Drug-Loaded Hydrogels with Stereolithographic 3D Printing
12. September 2017 Abstract 3D printing (3DP) technologies have been attracting much recent interest as new methods of fabricating medicines and medical devices. Of the…
Accelerating pharmaceutical development through predictive stability approaches
12. September 2017 Abstract There has been significant growth in the use of modeling tools to accelerate development and enhance pharmaceutical quality. Among these are…
Formation of mannitol core microparticles for sustained release with lipid coating in a mini fluid…
12. September 2017 Abstract The goal of this study was to prepare sustained release microparticles for methyl blue and aspartame as sparingly and freely water-soluble…
Influence of calcium carbonate and sodium carbonate gassing agents on pentoxifylline floating…
11. September 2017
Purpose
This study was to design and evaluate effervescent floating tablets with sustained release behaviour. Pentoxifylline is a water-soluble model drug with a short half-life,…
Metoprolol succinate controlled release multi unit particulate formulation for reconstitution using…
11. September 2017 Abstract The purpose of this work was to develop multi unit particulate formulation using fluid bed processor for the controlled release of Metoprolol…