Development, Pharmacokinetics and Antimalarial Evaluation of Dose Flexible 3D Printlets of Dapsone for Pediatric Patients
The focus of current studies was to fabricate dose flexible printlets of dapsone (DDS) for pediatric patients by selective laser sintering (SLS) 3D printing method, and evaluate its physicochemical, patient in-use stability, and pharmacokinetic attributes. Eight formulations were fabricated using Kollicoat® IR, Eudragit® L-100-55 and StarCap®as…
Sulfadiazine-based drug delivery systems prepared by an effective sol–gel process
21. June 2017 Abstract In the present contribution a versatile and sustainable strategy for the formulation of a drug delivery system for the controlled release of…
APIs & Excipients – A Global Regulatory Overview
20. June 2017
APIs & Excipients – A Global Regulatory Overview
Webinar
September 20, 2017 - 11:00am to 1:00pm
September 21, 2017 - 11:00am to 1:00pm
More Information & Registration…
Surface properties and morphology of selected polymers and their blends designed to mucoadhesive…
19. June 2017 Abstract In the mucoadhesive drug delivery systems the controlling mechanism is initiated by the wetting and swelling of the polymer matrix. In view of the…
Development of a solid dosage platform for the oral delivery of bilayer vesicles
19. June 2017
Abstract
Within this work, we develop vesicles incorporating sub-unit antigens as solid dosage forms suitable for the oral delivery of vaccines. Using a combination of trehalose, dextran and mannitol,…
Development and Optimization by Quality by Design Strategies of Frovatriptan Orally Disintegrating…
19. June 2017 BACKGROUND: Frovatriptan is a potent anti-migraine agent with unfavorable slow onset of action, available on the market as film-coated tablets.…
Continuous Manufacturing in Pharma
19. June 2017
16 hours hands-on seminar on continuous OSD pharma processing.
TTC Workshop 07 – 09 NOVEMBER 2017 in Binzen/Germany
More Information & Registration
pharma excipients
19. June 2017
Tablet Coating
TTC Workshop 19 – 21 September 2017 in Binzen/Germany
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Central composite design in HPMC granulation and correlations between product properties and process…
19. June 2017 Abstract Particulate solids have received great interest in many industrial fields for both marketing reasons and technological aspects. In this study…
Pellets and Micropellets for oral multiparticulate dosage forms
19. June 2017 TTC Workshop 10 - 12 October 2017 in Binzen/Germany More Information & Registration
Development of semisolid self-microemulsifying drug delivery systems (SMEDDSs) filled in hard…
19. June 2017 Abstract The study aimed to develop semisolid self-microemulsifying drug delivery systems (SMEDDSs) as carriers for oral delivery of aciclovir in hard…
Nanocrystals & loaded porous silica for increased oral bioavailability
19. June 2017 Nanocrystals & loaded porous silica for increased oral bioavailability Oral dosage form is considered as the most convenient and commonly employed route of…
Analysis of the origins of content non-uniformity in high-shear wet granulation
19. June 2017 Abstract In this study, the origins of granule content non-uniformity in the high-shear wet granulation of a model two-component pharmaceutical blend were…
Nanoemulsions as edible coatings
19. June 2017 Edible coatings are used to preserve food quality but may serve to immobilize active ingredients on the food surface. Nanoemulsions are effective systems for…
3D printed oral solid dosage forms containing hydrochlorothiazide for controlled drug delivery
19. June 2017 Abstract 3D printing has been recently employed in the design and fabrication of medicine, aiming to improve their properties and release behavior. In the…
An investigation into the effects of excipient particle size, blending techniques and processing…
16. June 2017 Abstract Powder blend homogeneity is a critical attribute in formulation development of low dose and potent active pharmaceutical ingredients (API) yet a…
Evaluation of retrograded starch as excipient for controlled release matrix tablets
15. June 2017
Abstract
High amylose starch (HAS) was retrograded by two different methods. The physicochemical properties of the retrograded materials were evaluated and structural changes were highlighted.…
Application of a Biodegradable Polyesteramide Derived from L-Alanine as Novel Excipient for…
15. June 2017 Abstract This pre-formulation study assays the capacity of the polyesteramide PADAS, poly (L-alanine-dodecanediol-L-alanine-sebacic), as an insoluble tablet…
Solid state properties and drug release behavior of co-amorphous indomethacin-arginine tablets…
15. June 2017 Abstract A promising approach to improve the solubility of poorly water-soluble drugs and to overcome the stability issues related to the plain amorphous…
Mechanical microencapsulation: The best technique in taste masking for the manufacturing scale…
15. June 2017 Abstract Drug taste masking is a crucial process for the preparation of pediatric and geriatric formulations as well as fast dissolving tablets. Taste…
Nanosizing techniques for improving bioavailability of drugs
15. June 2017 Abstract The poor solubility of significant number of Active Pharmaceutical Ingredients (APIs) has become a major challenge in the drug development process.…
Recent Trends in the Development of Chitosan-Based Drug Delivery Systems
13. June 2017 The AAPS PharmSciTech theme Recent Trends in the Development of Chitosan-Based Drug Delivery Systems includes a topical collection of 14 papers including both…
Comprehensive mucoadhesive study of anionic polymers and their derivate
12. June 2017 Aim The purpose was to compare the mucoadhesive properties of well-known anionic polymers such as alginate (AL), carboxymethyl cellulose (CMC),…
Heat Assisted Twin Screw Dry Granulation
12. June 2017 ABSTRACT A new ‘assisted' dry granulation method has been devised for the twin-screw granulator. The method may be beneficial to drug preparation as it…
Dissolution Testing of Herbal Medicines: Challenges and Regulatory Standards in Europe, the United…
12. June 2017 ABSTRACT Herbal medicines are the oldest method for treating diseases and at the same time still the most commonly used worldwide. Although people in…
A review of in vivo and in vitro aspects of alcohol-induced dose dumping
12. June 2017 Abstract This review provides a comprehensive list of in vivo and in vitro studies that have investigated alcohol induced dose dumping (AIDD) in modified…
Processing Thermally Labile Drugs by Hot-Melt Extrusion: The Lesson with Gliclazide
09. June 2017 Abstract The formation of molecularly dispersed amorphous solid dispersions by the hot-melt extrusion technique relies on the thermal and mechanical energy…
Gastroresistant gelatin films prepared by addition of cellulose acetate phthalate
09. June 2017
Abstract
Gastroresistant capsules are obtained mostly by using modified-release fill in hard capsules, or by coating the gelatin shell with acid-resistant polymers. Modification of the material used at the…
Development and evaluation of an oral fast disintegrating anti-allergic film using hot-melt…
09. June 2017 Abstract The main objective of this novel study was to develop chlorpheniramine maleate orally disintegrating films (ODF) using hot-melt extrusion…
3D printed tablets loaded with polymeric nanocapsules: an innovative approach to produce customized…
08. June 2017
Abstract
The generation of multi-functional drug delivery systems, namely solid dosage forms loaded with nano-sized carriers, remains little explored and is still a challenge for formulators. For the first…
A Comparative Assessment of Nanocomposites vs. Amorphous Solid Dispersions Prepared via…
08. June 2017
Abstract
Nanoextrusion was used to produce extrudates of griseofulvin, a poorly water-soluble drug, with the objective of examining the impact of drug particle size and polymeric matrix type–size of the…
Advanced Stability Predictions for Amorphous Pharmaceuticals
08. June 2017
Basic fundamentals of amorphous pharmaceutical stability predictions
Overcoming the limitations of RTD temperature sensors
Molecular mobility – considering the different molecular motions that exist in…
A novel hybrid solid dispersion film coat as a moisture barrier for pharmaceutical applications
08. June 2017 Abstract In the present study, a novel hybrid moisture barrier film coat, based on a solid dispersion of a stearic acid (SA) in hydroxypropyl cellulose…
Determination of the release mechanism of Theophylline from pellets coated with Surelease® − a water…
08. June 2017 Abstract The aim of this study was to investigate the water transport over free standing films based on the aqueous ethyl cellulose (EC) coating Surelease®…
Novel nano-cellulose excipient for generating non-Newtonian droplets for targeted nasal drug…
07. June 2017 PURPOSE: Thickening polymers have been used as excipients in nasal formulations to avoid nasal run-off (nasal drip) post administration. However, increasing…