Development, Pharmacokinetics and Antimalarial Evaluation of Dose Flexible 3D Printlets of Dapsone for Pediatric Patients
The focus of current studies was to fabricate dose flexible printlets of dapsone (DDS) for pediatric patients by selective laser sintering (SLS) 3D printing method, and evaluate its physicochemical, patient in-use stability, and pharmacokinetic attributes. Eight formulations were fabricated using Kollicoat® IR, Eudragit® L-100-55 and StarCap®as…
Sigachi Industries Pvt. Ltd. Indian site receives EXCiPACT GMP certification as pharmaceutical…
24. May 2017
EXCiPACT asbl is delighted to announce that the Sigachi Industries Pvt. Ltd.’s site in Dahej, India has recently been awarded an EXCiPACT GMP Certificate from SGS, one of EXCIPACT’s internationally-recognised…
Nanoporous Calcium Carbonate-Based Substrates for the Controlled Delivery of Functional Materials
24. May 2017
The overall aim of this project was to study `functionalised' calcium carbonates (FCCs) for use as a carrier for the controlled release of `actives,' by permeation and diffusion, and is being…
Co-spray Drying with HPMC as a Platform to Improve Direct Compaction Properties of Various Tablet…
24. May 2017 Abstract Many commonly used tablet fillers are not suitable for direct compaction process due to insufficient properties, mainly of flowability and…
Characterization of new functionalized calcium carbonate-polycaprolactone composite material for…
24. May 2017 Abstract A new mineral–polymer composite (FCC-PCL) performance was assessed to produce complex…
How to reduce the risk of tablet picking and sticking
23. May 2017 Summary Poor lubrication results in picking and sticking problems during production. These are one of the most common causes of tablet defects which result…
Workshop on Oral Controlled Release – APGI 6 July 2017 in Lille, France
23. May 2017
Lille - 6 July 2017
More Information & Registration
Drug Delivery Symposium
23. May 2017 27th -28th June 2017 Swissôtel - Zurich, Switzerland More Information & Online Registration…
A Review of Disintegration Mechanisms and Measurement Techniques
23. May 2017 Abstract Pharmaceutical solid dosage forms (tablets or capsules) are the predominant form to administer active pharmaceutical ingredients (APIs) to the…
The wettability and swelling of selected mucoadhesive polymers in simulated saliva and vaginal…
22. May 2017
Abstract
The surface properties play a particularly important role in the mucoadhesive drug delivery systems. In these formulations, the adsorption of polymer matrix to mucous membrane is limited by the…
Optimization and in-vitro Evaluation of Poly (lactic acid) /Mesalazine Microspheres as Drug Carriers
22. May 2017 ABSTRACT Purpose: The present study is intended to the preparation and optimization of controlled drug release microparticles based on polylactic acid and…
Continuous Heterogeneous Crystallization on Excipient Surfaces
22. May 2017 A novel continuous heterogeneous crystallization process is developed in which the active pharmaceutical ingredient (API) is crystallized directly on the…
The tracking of interfacial interaction of amorphous solid dispersions formed by water-soluble…
22. May 2017
Abstract
Herein, interfacial interactions of amorphous solid dispersion formed by nitrendipine (TDP) and two types of water-soluble polymers (polyvinyl pyrrolidone K30 (PVP) and polyethylene glycol…
Raw Materials/ Functional Excipients Roundtable
22. May 2017 How have advances in raw materials functionality, supply and quality affected the pharm/biopharma industry? Jason M. LePree, PhD, Gattefossé USA,…
Microstructural effects in drug release by solid and cellular polymeric dosage forms: A comparative…
22. May 2017 Abstract In recent studies, we have introduced melt-processed polymeric cellular dosage forms to achieve both immediate drug release and predictable…
Biopolymer in Gene Delivery
22. May 2017 Abstract Nowadays, biopolymers, a class of biomaterials, represent frontier area in the drug delivery systems. Drug release from nano- and microparticles is…
Novel Uses of Pharmaceutical Polymers as enabled by KinetiSol® Dispersing
22. May 2017 Poor water-solubility is a common characteristic of drug candidates in pharmaceutical development pipelines today. Various processes have been developed to…
Novel aspects on the direct compaction of ibuprofen with special focus on sticking
19. May 2017 Abstract Tableting of sticking active pharmaceutical ingredients (APIs) may cause time-consuming and costly complications. Therefore, the aim of this study…
Paediatric Over-the-Counter (OTC) Oral Liquids Can Soften and Erode Enamel
19. May 2017 Abstract: This study investigated the softening and erosive effects of various paediatric over-the-counter (OTC) oral liquids on deciduous teeth. Twenty…
Application of Soluplus to Improve the Flowability and Dissolution of Baicalein Phospholipid Complex
19. May 2017 Abstract: In this study, a novel ternary complex system (TCS) composed of baicalein, phospholipids, and Soluplus was prepared to improve the flowability and…
3rd Technical Seminar on Solubility Enhancement
18. May 2017
13th – 14th June 2017
University of Bradford
Centre for Pharmaceutical Engineering Science
Online Registration
Program & Registration
Seminar 2017-june…
Sugar Spheres: Improving clinical effectiveness with Multiparticulate drug delivery systems
18. May 2017 Presentation by Philipp Werner - pharm-a-spheres @ExcipientFest 2017…
Technology Solutions for small-molecule and biological therapies by spray drying
18. May 2017 Upperton's Technology Solutions using spray drying for small molecule and biological therapeutics include: • Stabilisation of biologicals •…
Sugars with different thickening power in high shear granulation
Sugars and sweeteners are common ingredients in foods and also in pharmaceutical industries. They are soluble and sticky ingredients and their processing in granulators may be difficult since they can easily adhere to mixer walls or…
Limited drug solubility can be decisive even for freely soluble drugs in highly swollen matrix…
17. May 2017 Abstract The aim of this study was to elucidate the importance of potential limited solubility effects for the control of drug release from hydrophilic…
Improving the Dissolution of Poorly Soluble APIs with Inorganic Solid Dispersions
17. May 2017 Changes in the way new chemical entities are developed and identified have led to a situation where many active pharmaceutical ingredient (API) innovations…
Cyclodextrin for pulmonary delivery?
16. May 2017 Design and development of dry powder sulfobutylether-β-cyclodextrin complex for pulmonary delivery of fisetin Abstract This study has…
Dipicolinic acid as a novel spore-inspired excipient for antibody formulation
16. May 2017 Abstract Ionic excipients are commonly used in aqueous therapeutic monoclonal antibody (mAb) formulations. Novel excipients are of industrial interest, with…
Development of modified release 3D printed tablets (printlets) with pharmaceutical excipients using…
16. May 2017 Abstract The aim of this study was to manufacture 3D printed tablets (printlets) from enteric polymers by single filament fused deposition modeling (FDM) 3D…
A quality by design (QbD) twin—screw extrusion wet granulation approach for processing water…
16. May 2017 Abstract In this study, a Quality by Design (QbD) approach was used to identify the effect of formulation parameters in a twin screw wet extrusion…
The Renaissance of Pellets is Promoting Innovative Technologies
16. May 2017 — In recent years, formulations based on pellets have been the trend. New technologies make it possible to circumvent property rights for active ingredients…
Matrix tablets based on amino acid-derived polyesteramide containing release modifiers
12. May 2017 Abstract The aim of this study was to develop controlled-release matrix tablets of ketoprofen (K) and dexketoprofen trometamol (DK-T), investigating a new…
Application of SeDeM expert systems in preformulation studies of pediatric ibuprofen ODT tablets
12. May 2017 Pediatric, ibuprofen containing orodispersible tablets (ODTs) were prepared using the SeDeM expert system methodology. In order to facilitate formulation,…
Novel in situ gel-forming solid dosage form (gfSDF) prepared by the simple syringe-based moulding: A…
11. May 2017 Abstract The aim of this study was to prepare and optimize a novel type of in situ gel-forming solid dosage form (gfSDF) to be used in the treatment of…
Synthesis of xanthan gum graft copolymer and its application for controlled release of highly water…
11. May 2017 Abstract Graft copolymers (XG-g-PNVP-1 to XG-g-PNVP-5) of xanthan gum (XG) and poly(N-vinyl-2-pyrrolidone) (PNVP) was synthesized by free radical…