Development, Pharmacokinetics and Antimalarial Evaluation of Dose Flexible 3D Printlets of Dapsone for Pediatric Patients
The focus of current studies was to fabricate dose flexible printlets of dapsone (DDS) for pediatric patients by selective laser sintering (SLS) 3D printing method, and evaluate its physicochemical, patient in-use stability, and pharmacokinetic attributes. Eight formulations were fabricated using Kollicoat® IR, Eudragit® L-100-55 and StarCap®as…
ADVANCING SOLID DOSE PROCESSING EFFICIENCY AND EFFECTIVENESS
25. April 2017
ADVANCING SOLID DOSE PROCESSING EFFICIENCY AND EFFECTIVENESS
Pharma is approaching continuous manufacturing with caution. However, equipped with fresh technical experience, plus decades of process design and…
Identification of Excipients for Stabilizing Fiberless Adenovirus as Biopharmaceuticals
24. April 2017 Abstract Reducing the promiscuous tropism of native adenovirus by using fiberless adenovirus is advantageous towards its use as a gene therapy vector or…
Personalized medicine: Inkjet printing of antiviral PCL nanoparticles and anticancer cyclodextrin…
24. April 2017 Personalized medicine: Inkjet printing of antiviral PCL nanoparticles and anticancer cyclodextrin inclusion complexes on bioadhesive film for cervical administr…
Microsponges – a novel carrier for resiquimod
24. April 2017 Abstract Microsponge is a polymeric drug delivery system composed of spherical particles ranged in micron size and loaded with active pharmaceutical…
Feasibility of mini-tablets as a flexible drug delivery tool
22. April 2017 Abstract Mini-tablets have potential applications as a flexible drug delivery tool in addition to their generally perceived use as multi-particulates. That…
Formalizing a Risk Assessment for Excipients
21. April 2017
Excipients serve a critical role in the production of final dosage forms for drug products and biologics. They facilitate the manufacturing process (e.g., anticaking agents) and protect, support, and enhance…
Priority Medicines for Children Exploring age-appropriate medicines and antibiotic use in children
21. April 2017 Priority Medicines for Children Exploring age-appropriate medicines and antibiotic use in children Abstract Children are not small adults, but rather a…
A New Role of Fine Excipient Materials in Carrier-Based Dry Powder Inhalation Mixtures: Effect on…
21. April 2017 Abstract The potential of fine excipient materials to improve the performance of carrier-based dry powder inhalation mixtures is well acknowledged. The…
Nurses experiences of medication administration to people with swallowing difficulties in aged care…
20. April 2017 Abstract Review question/objective: The objective of this review is to identify the experiences of nurses in administering oral medications to…
Flow Function of Pharmaceutical Powders Is Predominantly Governed by Cohesion, Not by Friction…
20. April 2017 Abstract The purpose of this study is to demonstrate that the flow function (FFc) of pharmaceutical powders, as measured by rotational shear cell, is…
Controlled precipitation for enhanced dissolution rate of flurbiprofen: Development of rapidly…
20. April 2017 Abstract Objective: The aim of this work was to investigate the potential of controlled precipitation of flurbiprofen on solid surface, in presence or…
Drug encapsulation in chitosan nanoparticles for dermal patch formulations
20. April 2017 The aim of this thesis was to develop drug encapsulation in chitosan nanoparticles for der- mal patch formulations. The thesis project included the…
Instant ODFs – Development of an intermediate, nanoparticle-based product platform for…
20. April 2017 Abstract The individualization of solid dosage forms to realize a flexible therapy for all patient groups is a topic which increasingly gains importance in…
Effect of micro-environment modification and polymer type on the in-vitro dissolution behavior and…
20. April 2017 AbstractThis study investigates the effects of micro-environment modification and polymer type on the in-vitro dissolution behavior and in-vivo performance of…
Optimized Furosemide Taste Masked Orally Disintegrating Tablet
20. April 2017 Abstract Optimized orally disintegrating tablets (ODTs) containing furosemide (FUR) were prepared by direct compression method. Two factors, three levels…
Melatonin: A Silent Regulator of the Glucose Homeostasis
20. April 2017
Melatonin: A Silent Regulator of the Glucose Homeostasis
Abstract
In the human organism, the circadian regulation of carbohydrates metabolism is essential for the glucose homeostasis and energy…
Developing Solid Oral Dosage Forms 2nd Edition
20. April 2017 Developing Solid Oral Dosage Forms: Pharmaceutical Theory and Practice, Second Edition illustrates how to develop high-quality, safe, and…
How to Optimize Fluid Bed Processing Technology – 1st Edition
20. April 2017 How to Optimize Fluid Bed Processing Technology: Part of the Expertise in Pharmaceutical Process Technology Series addresses the important…
Development of biodegradable implants for extended delivery of proteins
19. April 2017 Different drug delivery systems have been developed for peptides and proteins, with special interest on those that allow sustained parenteral release; they…
Mechanism-based selection of stabilization strategy for amorphous formulations: Insights into…
19. April 2017
Abstract
We developed a step-by-step experimental protocol using differential scanning calorimetry (DSC), dynamic vapour sorption (DVS), polarized light microscopy (PLM) and a small-scale dissolution apparatus…
The Effect of pH, Buffer Capacity, and Ionic Strength on Quetiapine Fumarate Release from Matrix…
19. April 2017
Abstract
The objective of this study was to investigate the effect of the different physiological parameters of the gastrointestinal (GI) fluid (pH, buffer capacity, and ionic strength) on the in vitro…
Evaluation of Rosin Gum and Eudragit® RS PO as a Functional Film Coating Material
19. April 2017 Abstract Polymers are essential tools in the research and development of new therapeutic devices. The diversity and flexibility of these materials have…
Risk Assessment Tool for Excipients (RATE)
19. April 2017 RATE Risk Assessment Tool for Excipients (RATE) has been designed and validated by MPI. RATE is a tool designed to provide a platform to…
Top drugs by sales in 2016: Who sold the blockbuster drugs?
19. April 2017 The year 2016 finished with a whimper insofar as mergers and acquisitions (M&As) were concerned. The preceding year — 2015 — had gone down in…
Amorphization of Atorvastatin Calcium by Mechanical Process: Characterization and Stabilization…
18. April 2017 Abstract The structural changes of crystalline atorvastatin upon high-energy ball milling at room temperature have been studied. The study investigates the…
Down-stream drug product processing of itraconazole nanosuspension: Factors influencing drug…
18. April 2017 Abstract There is more research required to broaden the knowledge on the downstream processing of nanosuspensions into solid oral dosage forms, especially…
Development and tableting of directly compressible powder from electrospun nanofibrous amorphous…
18. April 2017 Abstract This work was carried out to explore the unknown area of converting non-woven fibres, prepared by high speed electrospinning, into a directly…
Mucoactive agents for chronic, non-cystic fibrosis lung disease: A systematic review and…
18. April 2017 ABSTRACT Inhaled mucoactive agents are used in respiratory disease to improve mucus properties and enhance secretion clearance. The effect of mannitol,…
Particle Engineering in the Life Sciences Industry – 2nd PTC Symposium 2017
18. April 2017
Particle Engineering in the Life Sciences Industry - 2nd PTC Symposium 2017
Process Technology for Improved Product Properties
Tuesday 9th May 2017 -9.30 am – 5.00 pm
Registration…
Understanding How Excipients Affect Drug Quality
18. April 2017
At CPhI North America 2017, an AbbVie scientist will discuss how excipient property variability affects quality for amorphous solid dispersions and extended-release products.
Apr 18, 2017
By…
Continuous Manufacturing is Driving More Focus on Excipient Fitness for Purpose
18. April 2017 The deployment of continuous manufacturing (CM) is prompting the pharmaceutical industry to understand better the characteristics of the excipients they are…
One week to ExcipientFest Americas – Register now for the only event that is all about…
18. April 2017
Enjoy presentations about 3D Printing of tablets, sourcing excipients for biotech,regulatory updates and excipient technology innovation!
Take a look at the educational program here!
ExcipienFest…
Roles of Polysaccharides in Transdermal Drug Delivery System and Future Prospects
17. April 2018 This article reviews various polysaccharides used in transdermal drug delivery system. The system provides continuous controlled delivery of active…