Preparation and In Vitro Evaluation of Montelukast Sodium-Loaded 3D Printed Orodispersible Films for the Treatment of Asthma
This research aims to produce orodispersible films (ODFs) and determine their potential use in the oral delivery of montelukast sodium for asthma treatment and allergic rhinitis. ODFs were successfully developed by Three-dimensional (3D) printing using propylene glycol (PG), and hydroxypropyl methylcellulose (HPMC), polyethylene glycol 400 (PEG).…
DEVELOPMENT OF MICROPARTICLES FOR SUSTAINED RELEASE OF PROTEINS BASED ON LIPID AND SILICA MATERIALS
07. April 2017
Objectives of the thesis
Many protein drugs exhibit short half-lives in vivo and multiple dosing schemes and frequent injections are necessary to achieve therapeutic drug levels, which results in poor…
CRODAJAPAN’S SHIGA FACTORY RECEIVES EXCiPACT GMP CERTIFICATION AS PHARMACEUTICALEXCIPIENT SUPPLIERS
07. April 2017 CRODAJAPAN’S SHIGA FACTORY RECEIVES EXCiPACT GMP CERTIFICATION AS PHARMACEUTICALEXCIPIENT SUPPLIERS Brussels, 6 April 2017 EXCiPACT asbl is…
LubriTose™ PB The Ideal Choice for Placebo Manufacturing without the Mixing
07. April 2017
LubriTose™ PB The Ideal Choice for Placebo Manufacturing without the Mixing
Key benefits
• Enables dispensing straight from the drum to the hopper
• Eliminates any need for external…
Combined Control of Morphology and Polymorph in Spray Drying of Mannitol for Dry Powder Inhalation
06. April 2017 Abstract The morphology and polymorphism of mannitol particles were controlled during spray drying with the aim of improving the aerosolization properties…
Nanocrystal formulations of a poorly soluble drug. 2. Evaluation of nanocrystal liver uptake and…
06. April 2017 Abstract A stabilized high drug load intravenous formulation could allow compounds with less optimal pharmacokinetic profiles to be developed. Polyethylene…
An Investigation of the Anomeric Stability of Lactose Powder Stored Under High Stress Conditions
06. April 2017 Lactose has two anomeric forms: α- and β-lactose. This study investigated the stability of solid lactose stored under high temperature and humidity…
Experimental determination of residence time distribution in continuous dry granulation
06. April 2017 Abstract With increasing importance of continuous manufacturing, the interest in integrating dry granulation into a continuous manufacturing line is…
Phospholipids: Unique carriers for drug delivery systems
06. April 2017 Abstract The aim of this review is to draw attention on potential applications of phospholipids in drug delivery system through different sources,…
Cosmetics Product Regulation – Four Years afterits implementation
06. April 2017
Cosmetics Product Regulation - Four Years afterits implementation
Date: June 8th & 9th, 2017
Venue: Hilton Zurich Airport Hohenbuhlstrasse 10, 8152 Opfikon-Glattbrugg, Switzerland
Course…
Design of Experiments (DOE) for ProcessDevelopment and Validation
06. April 2017
Design of Experiments (DOE) for ProcessDevelopment and Validation
Date: June 1st & 2nd, 2017
Venue: WILL BE ANNOUNCED SOON, Washington, DC
Course "Design of Experiments (DOE) for Process…
Solvent-free protamine nanocapsules as carriers for mucosal delivery of therapeutics
05. April 2017 Abstract Local delivery of drugs and biopharmaceuticals for the treatment of inflammatory bowel disease remains a challenge. Innovative nanomedicines with…
Application of Sequential Design of Experiments to Develop Ibuprofen (400 mg) Tablets by Direct…
05. April 2017 Abstract A strategy based on sequential design of experiments (screening, optimization and confirmation) was used to develop a tablet formulation of…
Setting Ideal Lubricant Mixing Time for Manufacturing Tablets by Evaluating Powder Flowability
05. April 2017 Abstract We investigated the effectiveness of using Carr’s flowability index (FI) and practical angle of internal friction (Φ) as indexes for setting the…
Formulation and In vitro/In vivo evaluation of esomeprazole enteric coated minitablets
04. April 2017
Abstract
The objective of this study was to develop Esomeprazole solid dosage form as minitablets. The effect of coating thickness and percentage of fast disintegrants on the in vitro and in vivo…
Formulation and biopharmaceutical evaluation of bitter taste masking microparticles containing…
04. April 2017
Abstract
The objective of this study was to prepare and evaluate some physiochemical and biopharmaceutical properties of bitter taste masking microparticles containing azithromycin loaded in dispersible…
Effect of the characteristics of raw material ibuprofen on roller compaction and dissolution
04. April 2017 Abstract Ibuprofen is an oral analgesic usually processed by wet granulation. In this manuscript a new roller compaction process for ibuprofen is reported.…
USP Workshop on In Vitro Testing for Meeting Future Challenges for Veterinary Dosage Forms –…
04. April 2017 DT201702_A07.pdf…
Development of medicated foams that combine incompatible hydrophilic and lipophilic drugs for…
03. April 2017 Abstract The focus was on the development of medicated foam for incorporation of two incompatible active agents for psoriasis treatment; i.e., lipophilic…
Preparation and Evaluation of Sustained Release Colon Targeted Micropellets of Lornoxicam
03. April 2017 ABSTRACT The aim of the present work was to develop and evaluate sustained release colon targeted micropellets of lornoxicam in order to achieve release of…
A Polyvinylpyrrolidone-Based Supersaturable Self-Emulsifying Drug Delivery System for Enhanced…
03. April 2017 Abstract: A novel supersaturable self-emulsifying drug delivery system (S-SEDDS) of cyclosporine A (CyA)—a poorly water-soluble immunosuppressant—was…
Targeted delivery of hyaluronic acid to the ocular surface by a polymer-peptide conjugate system for…
03. April 2017 Abstract Hyaluronic acid (HA) solutions effectively lubricate the ocular surface and are used for the relief of dry eye related symptoms. However, HA…
Gaining insight on tablet capping tendency from compaction simulation
03. April 2017 Abstract Capping or lamination is an unsolved common problem in tablet manufacturing. Knowledge gaps remain despite an enormous amount of effort made in…
Oral Nanomedicine Based on Multicomponent Microemulsions for Drug-Resistant Breast Cancer Treatment
02. April 2017 The aim of this study is to demonstrate the enhanced therapeutic efficacy of anticancer drugs on drug-resistant breast cancer using multicomponent…
Development and evaluation of a polyvinyl alcohol based topical gel
02. April 2017 Abstract Topical drug delivery systems provide localized drug action. A hydrophilic polymer such as polyvinyl alcohol is a multi-faceted excipient that can…
Artemisinin loaded chitosan magnetic nanoparticles for the efficient targeting to the breast cancer
02. April 2017 Abstract Artemisinin, a natural anti-malarial agent, also possesses anti-proliferative and anti-angiogenic activity in cancer cells with very low toxicity…
Planetary Ball Milling and Supercritical Fluid Technology as a Way to Enhance Dissolution of…
02. April 2017 Abstract Dissolution of bicalutamide processed with polyvinylpyrrolidone by either supercritical carbon dioxide or ball milling has been investigated.…
Monitoring Fluid Bed Coating Processes with Real Time Imaging
01. April 2017 Introduction Innopharma Labs EyeconTM inline particle characterisation technology enables customers to measure particle size and shape during fluidised bed…
The functionality and stability of HPMCAS when used in hot-melt extrusion
31. March 2017
The majority of today’s new chemical entities are poorly water-soluble. One widely used means of overcoming that problem is to develop solid dispersions by mixing at the molecular level the drug candidate…
The effect of material attributes and process parameters on the powder bed uniformity during a…
31. March 2017 Abstract The objective of this work was to assess the effect of process parameters of a dosator nozzle machine on the powder bed uniformity of inhalation…
Nasal drug delivery: Design of a novel mucoadhesive and in situ gelling polymer
31. March 2017 Abstract The aim of the present study was to establish a novel polymeric excipient for liquid nasal dosage forms exhibiting viscosity increasing…
A Review of NSF / IPEC / ANSI 363 GMP Standard for Pharmaceutical Excipients – Findings and Best…
31. March 2017
ABSTRACT: CTwo year look back at the status of the NSF / IPEC / ANSI 363 GMP Standard for Pharmaceutical Excipients. What are we seeing as a certification body including best practices around risk assessment,…
Humidity Induced Phase Transformation of Poloxamer 188 and Its Effect on Physical Stability of…
31. March 2017
Abstract
Poloxamer 188, a commonly used emulsifying and solubilizing agent, was found to be the cause of crystallization of an investigational drug, AMG 579, from its amorphous solid dispersion…
Managing CNS Tumors: The Nanomedicine Approach
30. March 2017 Abstract Albeit the rapidly evolving knowledge about tumor biochemistry enables various new drug molecules to be designed as treatments, malignant central…
Polysaccharides as Excipients for Ocular Topical Formulations
30. March 2017 The topical treatment of extraocular or intraocular diseases, especially by eye drops, is the best accepted by patients. Treatment with eye drops, however,…