Relaxation tests for the time dependent behavior of pharmaceutical tablets: A revised interpretation
Relaxation tests are often used in the pharmaceutical field to assess the strain rate sensitivity of pharmaceutical powders and tablets. These tests involve applying a constant strain to the powder in the die and then monitoring the stress evolution over time. Interpreting these tests is complicated because different physical phenomena, mainly…
APV/IPEC Europe Excipient Conference 2017
23. March 2017 19.09. - 20.09.2017 | Berlin, Deutschland An update on regulatory and application developments More Information to follow…
Silica from Rice as New Drug Delivery Systems
23. March 2017 Abstract The pharmaceutical industry has seen an increased need of carriers or excipients design that allows the controlled release of a drug in the human…
Excipient Learning Lab by IPEC-AMERICAS
23. March 2017 IPEC-Americas Excipient Learning Lab; THE Authority and Resource for Education and Training in Pharmaceutical Excipients. Below…
Managing the delicate balance between Purchasing Strategy and Quality Requirements
23. March 2017
ABSTRACT: he current political environment, social climate, and economic challenges are creating enormous pricing pressures on the finished drug products marketed by the pharmaceutical industry regardless of…
Work plan for the CHMP Excipients Drafting Group (ExcpDG) for the revision of the guideline…
23. March 2017 Work plan for the CHMP Excipients Drafting Group (ExcpDG)…
Interdependence of Dosage Form Microstructure and Performance
22. March 2017 Our understanding of quality in pharmaceutical production has evolved significantly over the past decade. The quality-by-design initiative has proved to be a…
Formulation and characterization of mucoadhesive controlled release matrix tablets of captopril
22. March 2017 Abstract The purpose of this study is to characterize controlled release matrix tablets of captopril and to find out the physicochemical properties that…
Birch Bark Dry Extract by Supercritical Fluid Technology: Extract Characterisation and Use for…
22. March 2017 Abstract: Triterpene compounds like betulin, betulinic acid, erythrodiol, oleanolic acid and lupeol are known for many pharmacological effects. All these…
Preparation and In Vitro Evaluation of an Anti-bacterial In Situ Ophthalmic Gel
22. March 2017 Abstract: Background: Conventional dosage forms of neomycin sulphate suffer from different drawbacks like spillage, poor penetration, low bioavailability,…
9th Conference of the European Paediatric Formulation Initiative
22. March 2017 19 TO 21 SEPTEMBER 2017 IN WARSAW, POLAND The 9th EuPFI conference series is the ideal forum to learn, grow and to be inspired on the…
ROLE OF EXCIPIENTS IN DEVELOPMENT OF TOPICAL DOSAGE FORMS
21. March 2017 Abstract Topical route is the largest and easily accessible administration site for the different therapeutic entities. Although, physicochemical…
Additives and “Impurities” in Excipients – IPEC Webinar
21. March 2017
Wednesday, June 14, 2017 - 11:00am to 1:00pm
This webinar will discuss additives and “impurities” as they relate to excipients, including concomitant components, why they’re important to excipient…
Roquette Announces Commitment to Provide New Product Offerings
21. March 2017
New product offerings are low endotoxin, multi-compendial-grade materials for cell culture and biologic drug formulations. These products extend Roquette's commitment to helping customers save and sustain…
Extended release of flurbiprofen from tromethamine-buffered HPMC hydrophilic matrix tablets
21. March 2017 Abstract The pH-dependent solubility of a drug can lead to pH-dependent drug release from hydrophilic matrix tablets. Adding buffer salts to the…
Continuous Manufacturing & Excipients CMAs @ Highlights of IPEC Europe Forum 2017
21. March 2017
Continuous Manufacturing & Excipients CMAs @ Highlights of IPEC Europe Forum 2017
Highlights of IPEC Europe Forum 2017
IPEC Europe's annual Excipient Forum took place on 2 February in Monte Carlo,…
The 5th international Symposium on “Phospholipids in Pharmaceutical Research”
21. March 2017
September 18/19, 2017 in Heidelberg, Germany
OCULAR DRUG DELIVERY – STATE-OF-THE-ART AND NEW CONCEPTS – Featured Article in APV Drug…
21. March 2017 OCULAR DRUG DELIVERY – STATE-OF-THE-ART AND NEW CONCEPTS - Featured Article in APV Drug Delivery Focus Group Newsletter – 1/2016 By Lutz Franzen and…
SUDEEP PHARMA’S INDIAN SITE RECEIVES EXCiPACT GMP CERTIFICATION AS PHARMACEUTICAL EXCIPIENT…
21. March 2017
Brussels, 21 March 2017 - News Release EXCiPACT
EXCiPACT asbl is delighted to announce that the Sudeep Pharma Private Ltd’s Vadodara site in India has recently been awarded an EXCiPACT GMP…
Establishing a Formalized Risk Assessment for Excipients
21. March 2017
by: Frithjof Holtz, Merck KGaA, Darmstadt, Germany | Dec 06, 2016
Excipients serve a critical role in the production of final dosage forms for drug products and biologics. They facilitate the manufacturing…
A systematic study of molecular interactions of anionic drugs with a dimethylaminoethyl methacrylate…
20. March 2017 Abstract The methacrylate-copolymer Eudragit® EPO (EPO) has raised interest in solubility enhancement of anionic drugs. Effects on aqueous drug…
Surface area, volume and shape descriptors as a novel tool for polymer lead design and discovery
20. March 2017 Abstract In recent years, the demand and interest for functionalized polymers have increased for drug delivery purposes. Because of the increased interest,…
Orodispersible Films: Towards Drug Delivery in Special Populations
20. March 2017 Abstract Orodispersible films (ODF) hold promise as a novel delivery method, with the potential to deliver tailored therapies to different patient…
Cyclosporine A delivery to the eye: a comprehensive review of academic and industrial efforts
20. March 2017 Abstract Local ocular delivery of cyclosporine A (CsA) is the preferred method for CsA delivery as a treatment for ocular inflammatory diseases such as…
Supercritical antisolvent co-precipitation of rifampicin and ethyl cellulose
20. March 2017 Abstract Rifampicin-loaded submicron-sized particles were prepared through supercritical anti-solvent process using ethyl cellulose as polymeric…
Evaluation of Analytical and Sampling Errors in the Prediction of the Active Pharmaceutical…
20. March 2017 Abstract Purpose A near-infrared (NIR) spectroscopic method was developed for real time analysis of the active pharmaceutical ingredient (API) in blends…
Physicochemical characterization and compatibility study of roflumilast with various pharmaceutical…
20. March 2017 Abstract Roflumilast (RFL), a newly approved and highly selective phosphodiesterase 4 inhibitor for the treatment of severe chronic obstructive…
Carobomer Based Controlled Release Designs of Atorvastatin Calcium Tablets Evaluated Using Quality…
20. March 2017 ABSTRACT The study carried out here was focused on developing conventional monolithic controlled release matrix tablet of Atorvastatin calcium using…
Characterization of orally disintegrating films: A feasibility study using an electronic taste…
20. March 2017 Abstract In the early development stage of orally disintegrating films (ODFs), suitable evaluation methods must be used. The aim of this study was to…
Pharmaceutical Lyophilisation Summit
20. March 2017 Berlin - 27 - 28 April, 2017 This premier event provides the appropriate platform to discuss and network with peers involved in…
Testing PAT under realistic conditions
20. March 2017
Determining the drying endpoint in fluidized bed processes
Whatever the process, whether conti or batch: Process Analytical Technology (PAT) and parametric release are currently the hottest topics in…
Bridging Justifications: Supporting the Safety of Excipients in Generic Drug Products (Presentation)
17. March 2017 Outline • Excipient safety review in generic drug applications • Bridging justifications for excipients in generic drugs – What is their utility?…
EC Unveils Revised Guideline on Pharmaceutical Excipients
16. March 2017 The European Commission on Tuesday opened for public comment a revised guideline concerning the list of excipients, defined as any constituents of a medicinal…
Formulation and PEGylation optimization of the therapeutic PEGylated phenylalanine ammonia lyase for…
16. March 2017 Abstract Phenylketonuria (PKU) is a genetic metabolic disease in which the decrease or loss of phenylalanine hydroxylase (PAH) activity results in…