Relaxation tests for the time dependent behavior of pharmaceutical tablets: A revised interpretation
Relaxation tests are often used in the pharmaceutical field to assess the strain rate sensitivity of pharmaceutical powders and tablets. These tests involve applying a constant strain to the powder in the die and then monitoring the stress evolution over time. Interpreting these tests is complicated because different physical phenomena, mainly…
Advances and development in transdermal drug delivery system-A Review
16. March 2017
Abstract
It is one of the best pharmaceutical dosage forms for those patients, they cannot take medicaments orally. Transdermal drug delivery system (TDDS) established itself as an integral part of novel…
Formulation of hydrophobic peptides for skin delivery via coated microneedles
16. March 2017
Abstract
Microneedles (MNs) have been investigated as a minimally-invasive delivery technology for a range of active pharmaceutical ingredients (APIs). Various formulations and methods for…
Colon-targeted delivery of solubilized bisacodyl by doubly enteric-coated multiple-unit tablet
16. March 2017 Abstract A doubly enteric-coated multiple-unit tablet (DET) of bisacodyl (BD) was formulated to selectively deliver the stimulant laxative to the large…
Swelling and mass transport properties of nanocellulose-HPMC composite films
15. March 2017 Abstract Composite films were sprayed from mixtures of water soluble hydroxypropyl methylcellulose (HPMC) and either nanofibrillated cellulose (NFC) or…
Pharmacokinetics and correlation between in vitro release and in vivo absorption of bio-adhesive…
15. March 2017 Abstract The present study was designed to prepare and compare bio-adhesive pellets of panax notoginseng saponins (PNS) with hydroxy propyl methyl…
Prosopis alba exudate gum as novel excipient for fish oil encapsulation in polyelectrolyte bead…
15. March 2017 Abstract In this work, a bottom-up approach based on the study of polyelectrolyte interactions was performed in order to evaluate the effect of Prosopis…
Multifractal and mechanical analysis of amorphous solid dispersions
15. March 2017 Abstract The formulation of lipophilic and hydrophobic compounds is a challenge for the pharmaceutical industry and it requires the development of complex…
Insight into a Novel Strategy for the Design of Tablet Formulations Intended for Direct Compression
15. March 2017 Abstract In a recent study, it was demonstrated that improving flow of a model poorly flowing and poorly compactable drug substance, acetaminophen, via…
CARBAGAS DOMDIDIER SITE IN SWITZERLAND RECEIVES EXCiPACT GMP CERTIFICATION AS PHARMACEUTICAL…
15. March 2017 Brussels, 14 March 2017 EXCiPACT asbl is delighted to announce that the Carbagas Domdidier site has recently been awarded an EXCiPACT Certificate from…
TA Associates Announces Investment in Ideal Cures
14. March 2017
March 14, 2017 12:00 AM Eastern Daylight Time
BOSTON & MUMBAI, India--(BUSINESS WIRE)--TA Associates, a leading global growth private equity firm, today announced it has completed an…
Introduction to VPA (vaporized peracetic acid) sterilization; A new path to innovation and…
14. March 2017
Traditional sterilization methods, such as ethylene oxide (EO), gamma radiation can leave behind dangerous carcinogenic residuals or even damage and degrade a product’s materials or packaging. REVOX has…
Delivering the Promise of Continuous Secondary Manufacturing
14. March 2017
• Drivers for continuous secondary OSD
• Technical barriers for implementation
• TSG case study ( residence time distribution and process
understanding examples)
• Proposed focus areas for future…
Stability of pharmaceutical salts in solid oral dosage forms
14. March 2017 Abstract Using pharmaceutical salts in solid dosage forms can raise stability concerns, especially salt dissociation which can…
A retrospective and observational analysis of harmful excipients in medicines for hospitalised…
13. March 2017
Background Medicines used in neonates contain different excipients, which may not be safe in this age group.
Objective To analyse the frequency at which hospitalised neonates are exposed to harmful…
Using Nanotechnology to Improve Excipients – IPEC Webinar Mar 15, 2017
13. March 2017 Nanotechnology, the science of the very small, is rapidly evolving. It enables exciting improvements in many applications, and excipients are…
Mesoporous Silica: A Drug Delivery Platform for Solubility Enhancement
13. March 2017 Grace will present a detailed discussion of the mechanisms of silica for solubility enhancement for BCS class II drugs. We will introduce…
Characterisation of the Pore Structure of Functionalised Calcium Carbonate Tablets by Terahertz…
12. March 2017 Abstract Novel excipients are entering the market to enhance the bioavailability of drug particles by having a high porosity and thus providing a rapid…
Exploring Canine-Human Differences in Product Performance. Part II: Use of Modeling and Simulation…
12. March 2017 Abstract This study explored the in vivo performance of three oral ciprofloxacin formulations (oral solution, fast, or slow dissolving tablets) in beagle…
New possibilities using AFFINISOL™ excipients Exploring a platform of tailored polymers for…
12. March 2017 New possibilities using AFFINISOL™ excipients Exploring a platform of tailored polymers for solubility enhancement AFFINISOL™ polymers are…
Advancements in the Development and Manufacturing of Nanosuspension Based Drug Products
11. March 2017 Several nanoparticulate drug products joined the market in the last decade with commercial success. More recently, generic copies of…
Understanding the Filmcoating Process
10. March 2017
ABSTRACT: The operator of a filmcoating process typically has no control over the properties of tablet core and filmcoating material. Thorough understanding of the flmcoating process is therefore essential for…
Medical Marijuana: Improving stability with novel delivery methods
10. March 2017
ABSTRACT: Medical Marijuana products can be one of most promising therapeutics in the near future. However, its pharmaceutical use poses many formulation challenges: absortion, dosage variability, strain…
Ensuring Patient Safety through Appropriate Impurity Evaluation
10. March 2017
ABSTRACT: The presence of undetected impurities in drug products can lead to devastating side effects. For example, Diethylene Glycol (DEG) as an impurity has troubled the drug product industry for nearly 75…
Continuous Processing of Solid Oral Dose Forms
10. March 2017
Traditional concepts of batch processing have given way to new paradigms in continuous processing for the manufacturing solid oral products. This transition from batch manufacture to continuous,…
Canyour innovative biomedical research help astronauts get to Mars? A request for proposals
10. March 2017
Canyour innovative biomedical research help astronauts get to Mars? A request for proposals
The newly established Translational Research Institute (TRI) at Baylor College of Medicine seeks innovative and…
2017 Gattefossé Award for Excellence in Research and Development with Lipid-based Excipients
10. May 2017 Gattefossé North America is sponsoring an annual award to recognize scientific excellence and significant contributions to the field of…
2017 EXCIPACT STANDARDS REVISION – STAKEHOLDER CONSULTATION OPENS
09. March 2017
The EXCiPACT Board commissioned a project team to undertake a revision of the EXCiPACT standards to align them to ISO 9001:2015 and ISO/IEC 17021-1:2015 without change or enhancement of any individual…
Sugar Spheres: Improving clinical effectiveness with Multiparticulate drug delivery systems
09. March 2017
ABSTRACT: The upcoming of biopharmacy in the 1950s resulted in various delayed, prolonged, sustained, extended, repeat action or in one word controlled release formulations. The establishment of those…
Fingerprinting Biologics Drugs Using Drop Coat Deposition Confocal Raman (DCDCR) Spectroscopy
09. March 2017
ABSTRACT: Counterfeit drugs pose a significant and fast-growing threat to public health and safety. The incident of counterfeit Avastin® in the United States demonstrates the vulnerability of the supply chain…
A Review of NSF / IPEC / ANSI 363 GMP Standard for Pharmaceutical Excipients – Findings and Best…
09. March 2017
ABSTRACT: Two year look back at the status of the NSF / IPEC / ANSI 363 GMP Standard for Pharmaceutical Excipients. What are we seeing as a certification body including best practices around risk assessment,…
Implementation strategy of ICH Q3D guideline
09. March 2017
Introduction
The purpose of this document is to address specific considerations to enable the practical implementation of ICH Q3D Guideline for Elemental Impurities in the European Union. It is intended…
Vaccine Excipient & Media Summary – Excipients Included in U.S.…
09. March 2017 Vaccine Excipient & Media Summary - Excipients Included in U.S. Vaccines, by Vaccine In addition to weakened or killed disease antigens (viruses or…
The biopharmaceutical classification system of excipients – Introduction to Article
09. March 2017 Teófilo Vasconcelos1,2,3,4, Sara Marques2,5 & Bruno Sarmento3,4,6 1BIAL-Portela & Cª, S.A. À Avenida da Siderugia Nacional, Trofa,…