Relaxation tests for the time dependent behavior of pharmaceutical tablets: A revised interpretation
Relaxation tests are often used in the pharmaceutical field to assess the strain rate sensitivity of pharmaceutical powders and tablets. These tests involve applying a constant strain to the powder in the die and then monitoring the stress evolution over time. Interpreting these tests is complicated because different physical phenomena, mainly…
In Vitro and In Vivo Evaluation of PEGylated Layer-by-Layer Polyelectrolyte-Coated Paclitaxel…
24. October 2016 Abstract Drug nanocrystals (NCs) are colloidal dispersions composed almost entirely of drug. As such, there is substantial interest in targeting them to…
Drug delivery techniques for buccal route: formulation strategies and recent advances in dosage form…
24. October 2016 Abstract The buccal mucosa has been investigated for the local drug therapy and the systemic delivery of potent peptides, proteins, and other small drug…
The development of sustained release drug delivery platforms using melt-extruded cellulose-based…
24. October 2016 Objectives This research examined the application of hot melt extrusion (HME) in the preparation of matrix formulations containing hydroxypropyl…
Topical Formulation: Moving From Art to Science
24. October 2016 Analytics and science-based approaches are shedding more light on these complex dosage forms, promising to improve process control and product design.…
Scientific and regulatory approaches to confirm quality and improve patient perceptions of generic…
24. October 2016 Abstract The rapidly growing medical expense going with aging population in Japan requires the use of generic products derived from off-patent active…
Oral sustained-release suspension based on a lauryl sulfate salt/complex
24. October 2016
Abstract
The objective of this study was to evaluate the feasibility of lauryl sulfate (LS) salt/complex as a novel carrier in oral sustained-release suspensions. Mirabegron, which has a…
Hybrid polymeric matrices for oral modified release Desvenlafaxine succinate tablets
24. October 2016 Purpose Desvenlafaxine succinate (DSV) is a water soluble anti-depressant drug, which is rapidly absorbed after oral administration exaggerating its…
High throughput microencapsulation of Bacillus subtilis in semi-permeable biodegradable polymersomes…
24. October 2016 Encapsulating bacteria within constrained microenvironments can promote the manifestation of specialized behaviors. Using double-emulsion droplet-generating…
INNOVATIVE USES OF ETHYLENE VINYL ACETATE POLYMERS FOR ADVANCING HEALTHCARE
20. October 2016 ABSTRACT Ethylene vinyl acetate (EVA) has a long and successful history of innovation in medical packaging, medical devices, and pharmaceutical…
Dual Use Excipients
20. October 2016 What is a “Dual Use Excipient”? A substance that has a monograph in the USP but is manufactured and used predominantly as an…
Co-Processed Excipients – ein neuer Formulierungsansatz für Solida
19. October 2016
Interessieren Sie sich für alternative Formulierungsansätze bei der Direkttablettierung? Dann sollten Sie auf gar keinen Fall den Vortrag von Albrecht Krämer von Meggle verpassen. Auf dem…
3. PHARMAFESTSTOFF-FORUM
19. October 2016
15. - 16. November 2016
Würzburg - Germany
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3D-Printed Drugs: What Does the Future Hold?
19. October 2016 3D-Printed Drugs: What Does the Future Hold? In August 2015, the U.S. Food and Drug Administration (FDA) approved Aprecia Pharmaceuticals Company’s…
A Vision for 3D Printing in Pharma Manufacturing
19. October 2016
Three-dimensional (3D) printing—a type of additive manufacturing (AM)—has the potential to be the “next great step” in pharmaceutical manufacturing, enabling fabrication of specialty drugs and…
3D PRINTING OF ORAL DOSAGE FORMS
19. October 2016 3D PRINTING OF ORAL DOSAGE FORMS 3D printing is an innovative manufacturing process whereby an object is built up layer by layer from a 3D computer…
An Overview on Emerging Trends in Immediate Release Tablet Technologies
19. October 2016 Abstract Tablet is the most popular among all dosage forms existing today because of its convenience of self-administration, compactness and easy…
Taking control of sustained drug release – with Parteck® SRP 80
18. October 2016 See further excipients videos on pharma-excipients.ch
Trehalose monooleate: a potential anti- aggregation agent for stabilization of proteins
18. October 2016
Protein aggregation is a major problem of therapeutic proteins because aggregation decreases their therapeutic activity, shelf life and induces immunogenicity. Stabilization against aggregation is commonly…
The influence of electrostatic properties on the punch sticking propensity of pharmaceutical blends
18. October 2016 Purpose The present study details characterisation of the electrostatic properties of a range of active pharmaceutical ingredients (APIs) and blends and…
Dual release and molecular mechanism of bilayered aceclofenac tablet using polymer mixture
Abstract
The objectives of the present study were to develop a controlled-release bilayered tablet of aceclofenac (AFN) 200 mg with dual release and to gain a mechanistic understanding of the enhanced sustained release…
Development of controlled-release cisplatin dry powders for inhalation against lung cancers
18. October 2016 Abstract The present study focuses on the development of dry powders for inhalation as adjuvant chemotherapy in lung cancer treatment. Cisplatin was…
Review on Chronotherapy: A Novel Drug Delivery System
18. October 2016 ABSTRACT The goal in drug delivery research is to meet therapeutic needs relating to particular pathological conditions by developing new…
Controlled Release Products
17. October 2016 Controlled Release (CR) products are designed to maintain constant therapeutic plasma concentration of the drug within the therapeutic range of the drug…
“Innovation in Drug Delivery – A Novel Single Dose Nasal Applicator – PharmaLunch SAPhW
17. October 2016
"Innovation in Drug Delivery – A Novel Single Dose Nasal Applicator - PharmaLunch SAPhW
28th October 2016 in Basel, Switzerland
presented by Claudia Mattern, Dr. rer. nat., Adj. Prof.…
Edible Films and Coatings: Fundamentals and Applications – Food Preservation Technology Series
17. October 2016 Summary The search for better strategies to preserve foods with minimal changes during processing has been of great interest in recent decades.…
Kappa-carrageenan/halloysite nanocomposite hydrogels as potential drug delivery systems
17. October 2016 Abstract Novel kappa-carrageenan (Kc)/halloysite nanotube (HNT) nanocomposite hydrogels were synthesized via physical crosslinking for the…
Cytotoxicity of methylcellulose-based films containing graphenes and curcumin on human lung…
17. October 2016 Abstract The present study focused on the preparation, physico-chemical, and biological characterization of several composite films containing graphene…
Application of Physiologically Based Absorption Modeling to Characterize the Pharmacokinetic…
15. October 2016 A previously presented physiologically-based pharmacokinetic model for immediate release (IR) methylphenidate (MPH) was extended to characterize the…
Influence of processparameters on the preparation of pharmaceutical films by electrostatic…
15. October 2016 Influence of processparameters on the preparation of pharmaceutical films by electrostatic powderdeposition Abstract Electrostatic powder deposition…
Effect of solvent on retarding the release of diltiazem HCl from Polyox-based liquisolid tablets
15. October 2016 Objectives The aim of this work was to investigate the use of liquisolid technique to sustain the release of a model highly soluble drug, diltiazem HCl,…
Influenceof different excipients on the properties of hard gelatin capsules withmetamizole sodium
15. October 2016 Influenceof different excipients on the properties of hard gelatin capsules withmetamizole sodium Abstract Metamizole is an effective non-opioid…
Solubility issues? Join the 2nd International Symposium on Solubility Enhancement!
14. October 2016
November 09-10, 2016
Darmstadt, Germany
High-Throughput Excipient Discovery Enables Oral Delivery of Poorly Soluble Pharmaceuticals
13. October 2016 Synopsis We identify a polymer discovery paradigm to complement oral drug discovery efforts. Rapid chemistry, screening, and in vitro−in vivo testing of…
Functional solutions for soft gel formulation
13. October 2016 Easy to swallow and featuring an attractive translucent appearance – soft gelatine capsules or softgels have become one of the most popular dosage forms for…