Breast Cancer Awareness Month 2024
Breast Cancer Awareness Month is an international health campaign that takes place every October. The Breast Cancer Awareness Month aims to raise awareness about breast cancer, encourage early detection, and support research and treatment. The initiative was started in 1985 as a partnership between the American Cancer Society and the pharmaceutical…
Functional solutions for soft gel formulation
13. October 2016 Easy to swallow and featuring an attractive translucent appearance – soft gelatine capsules or softgels have become one of the most popular dosage forms for…
More Clarity Sought in FDA’s Inactive Ingredient Database Regarding Drug Delivery Devices
12. October 2016
FDA and the excipient industry are giving more thought to how the inactive ingredient database (IID) can be improved to better support the development of emerging dosage forms, including drug delivery…
Challenge of paediatric compounding to solid dosage forms sachets and hard capsules – Finnish…
11. October 2016 Objectives The study evaluated the quality of compounded sachets and hard gelatine capsules and their feasibility in paediatric drug administration.…
Influence of dissolution-modifying excipients in various pharmaceutical formulations on electronic…
11. October 2016 Abstract The overall performance of a potentiometric electronic tongue (ET) as well as the sensitivity and selectivity pattern of particular…
Recommended strategies for the oral administration of paediatric medicines with food and drinks in…
11. October 2016 Objectives This review focuses on the recommended strategies for the oral administration of paediatric medicines with food in the context of their…
Very fast dissolving acid carboxymethylcellulose-rifampicin matrix: Development and solid-state…
11. October 2016 Abstract One of the main obstacles to the successful treatment of tuberculosis is the poor and variable oral bioavailability of rifampicin (RIF), which…
Continuous Production of Itraconazole-based Solid Dispersions by Hot Melt Extrusion: Preformulation,…
The purpose of this work was to increase the solubility and the dissolution rate of itraconazole, which was chosen as the model drug, by obtaining an amorphous solid dispersion by hot melt extrusion. Therefore, an initial preformulation…
In-vitro investigation regarding the effects of Gelucire® 44/14 and Labrasol® ALF on the secretory…
11. October 2016
Abstract
In this present study, the secretory transport of P-gp substrates, rhodamine 123 and digoxin, was evaluated using a Caco-2/HT29-MTX co-culture characterized by an efflux mechanism and a…
Functional performance of chitosan/Carbopol 974P NF matrices in captopril tablets
11. October 2016 ABSTRACT Chitosan and Carbopol have been used to form a complex through an electrostatic interaction between the protonated amine (NH3+) group of…
Functionalised calcium carbonate: a next-generation mineral excipient
11. October 2016
Orally disintegrating tablets (ODTs) are a preferred dosage form compared with conventional tablets because of the numerous advantages they offer, such as rapid dissolution and fast onset of action.
To…
Microparticle surface layering through dry coating: impact of moisture content and process…
10. October 2016 Abstract Objectives The aim of this study was to investigate the influence of process parameters during dry coating on particle and dosage form…
Time to change the paradigm of children’s medicines from liquid formulations to flexible solid oral…
10. October 2016 Worldwide, people prefer a liquid formulation when pediatric medicines have to be given orally. The syrups and suspensions can be dosed flexibly…
Age-appropriate and acceptable paediatric dosage forms: Insights into end-user perceptions,…
10. October 2016 Abstract A lack of evidence to guide the design of age-appropriate and acceptable dosage forms has been a longstanding knowledge gap in paediatric…
Pharmaceutical Excipients: Properties, Functionality, and Applications in Research and Industry
09. October 2016 Description This book provides an overview of excipients, their functionalities in pharmaceutical dosage forms, regulation, and selection for…
Development and evaluation of mosapride citrate orally disintegrating tablets for dogs
09. October 2016 ABSTRACT The purpose of the study was to prepare orally disintegrating tablets (ODTs) of mosapride citrate for dogs with fast disintegration and low…
Capsugel Launches Vcaps for Enteric Protection & Delayed Release
08. October 2016
Capsugel Launches Vcaps for Enteric Protection & Delayed Release
Capsugel recently announced the launch of its Vcaps® Enteric capsules, a new functional capsule technology that achieves…
European Pharmacopoeia prepares for the future through exchange with stakeholders
08. October 2016
International conference: “European Pharmacopoeia: Tackling future challenges of the Quality of Medicines together”, 27-28 September 2016, Tallinn, Estonia
The EDQM’s international conference held in Tallinn…
Development and characterization of the voriconazole loaded lipid-based nanoparticles
08. October 2016
Abstract
The number of topical fungal infections is growing, mostly owing to immunosuppressive therapy. Several topical fungal infections, such as eye mycoses, can be treated by local administration of…
Free webinar on equipment cleaning after processing EUDRAGIT® coating
08. October 2016
The webinar will be broadcast on: October 25, 2016 10:00am EDT (New York)
Information & Registration
Development of Polycaprolactone/Poly(Vinyl Alcohol)/Clay Microparticles by Spray Drying
07. October 2016 In this study, nanostructured microparticles was developed with polycaprolactone (PCL), poly(vinyl alcohol) (PVAL) and nanoparticles of the commercial…
Impact of Quality by Design on Topical Product Excipient Suppliers, Part I: A Drug…
07. October 2016 Abstract Quality by design (QbD) is a scientific and risk-based approach to product development that begins at the product concept stage. This article…
Optimization of Melt in Mouth Tablets of Palonosetron HCl using Full Factorial Design
04. October 2016 Palonosetron HCl is a 5HT3 antagonist licensed for the prevention of acute chemotherapy-induced nausea and vomiting (CINV) associated with highly emetogenic…
Multispectral UV imaging for surface analysis of MUPS tablets with special focus on the pellet…
04. October 2016
Abstract
In the present study the applicability of multispectral UV imaging in combination with multivariate image analysis for surface evaluation of MUPS tablets was investigated with respect to the…
Investigations on Drying and Tribocharging Behaviour of Pharmaceutical Powders in a Fluidized Bed…
04. October 2016 Abstract Among various methods for drying pharmaceutical granules in the pharmaceutical industry, fluidized bed drying is commonly used due to its high…
Functionality of Benecel K4M/Carbopol 971P NF matrices in direct compression tablets for controlled…
Functionality of Benecel K4M/Carbopol 971P NF matrices in direct compression tablets for controlled release
The aim of this work is the assessment of the eventual enhancing effects of Carbopol 971P NF on the performance of Benecel…
Excipients Insight September 2016 – IPEC Europe
03. October 2016
This edition of Excipients Insight comes to you hoping you had a most agreeable summer break. But 'excipient work is never done', to paraphrase a well-known saying and we are now very engaged in preparing…
Formulation of orodispersible films for paediatric therapy: investigation of feasibility and…
01. October 2016
Objectives
Orodispersible films (ODF) were formulated to facilitate tetrabenazine (TBZ) administration to paediatric population for the treatment of hyperkinetic movement disorders.
Methods
ODF…
Plant Derived Polymers, Properties, Modification & Applications
01. October 2016 Plant Derived Polymers, Properties, Modification & Applications Abstract Current polymeric research has explored various applications in drug delivery…
The phenomenon of tablet flashing — Its impact on tableting data analysis and a method to eliminate…
01. October 2016 Abstract Flashing at tablet edges, an inevitable phenomenon when tableting a plastically deforming material under a high pressure, can introduce…
Hot-melt extrusion as a continuous manufacturing process to form ternary cyclodextrin inclusion…
01. October 2016 Abstract The aim of this study was to evaluate hot-melt extrusion (HME) as a continuous process to form cyclodextrin (CD) inclusion complexes in order to…
Nasal drug absorption from powder formulations: The effect of three types of hydroxypropyl cellulose…
30. September 2016 Abstract Despite the numerous advantages of powder formulations, few studies have described their nasal drug absorption. The first aim of this study…
Lornoxicam Immediate Release Tablet Using Spray-Dried Cellulose Nanofibers (NFC) as Novel Tablet…
30. September 2016
Abstract: The choice of proper excipients is one of the key factors for successful formulation of pharmaceutical dosage forms. Increasing number of new therapeutic compounds suffers from poor…
Design and Evaluation of Solubility Enhancement of Poorly Soluble Drugs using Liquid Solid Compacts
30. September 2016
ABSTRACT
Oral dosage form is the physical form of a dose of a chemical compound used as a drug or medication intended for administration or consumption by the oral route. The poor dissolution rate of…
Imaging wet granules with different flow patterns by electrical capacitance tomography and microwave…
30. September 2016 Abstract The moisture content of granules in fluidised bed drying, granulation and coating processes can typically be between 1%~25%, resulting in…