Virtual screening of drug materials for pharmaceutical tablet manufacturability with reference to sticking
Abstract
The manufacturing of pharmaceutical solid dosage forms, such as tablets involves a large number of successive processing operations including crystallisation of the drug substance, granulation, drying, milling, mixing of the formulation, and compaction. Each step is fraught with manufacturing problems. Undesired adhesion of powders to…
Formulation and Evaluation of Solid Self Micro-Emulsifying Drug Delivery System (S-SMEDDS) of…
06. July 2016 ABSTRACT The main objective of this study was to prepare a solid self micro-emulsifying drug delivery system (S-SMEDDS) by spray drying liquid SMEDDS with…
SheffCoat™ Glide- Improving the Ease of Swallowing One Tablet at a Time
06. July 2016 SheffCoat™ Glide- Improving the Ease of Swallowing One Tablet at a Time Most often, large or irregular shaped tablets are very difficult to swallow,…
One step up: achieving compliance for excipient GMPs
05. July 2016 Kaat Bracquiné, quality and regulatory affairs, Capsugel explains how to achieve compliance with the new EU guidelines for excipient GMPs. Last…
Can analytical testing of excipients be ‘volkswagenized’?
05. July 2016 Pecuniary gain, when stretched past the altruistic; carried through the protestant means to salvation and, past Adam Smith’s ‘hidden hand’ hypothesis; usually…
EXCIPACT CERTIFICATION SCHEME: TRIENNIAL REREGISTRATION & RECERTIFICATION PROCESS OFF TO A…
05. July 2016 EXCIPACT CERTIFICATION SCHEME: TRIENNIAL REREGISTRATION & RECERTIFICATION PROCESS OFF TO A SUCCESSFUL START NEWS RELEASE - Brussels, 5th July, 2016…
Impact of Extrusion Process Parameters on Drug Recovery and DissolutionPerformance of Solid…
05. July 2016 Impact of Extrusion Process Parameters on Drug Recovery and DissolutionPerformance of Solid Dispersions of Ritonavir and AFFINISOL TM HPMC HME This technical…
Formulation and Evaluation of Chlorhexidine Medicated Chewing Gums by Different Methods
04. July 2016 Aim: The aim of this work is development and evaluation of chlorhexidine medicated chewing gums by different methods and to study the influence of different…
Anti-PEG antibodies in the clinic: Current issues and beyond PEGylation
04. July 2016 Abstract The technique of attaching the polymer polyethylene glycol (PEG), or PEGylation, has brought more than ten protein drugs into market. The surface…
Outlining critical quality attributes (CQAs) as guidance for the development of orodispersible films
04. July 2016 Context: Orodispersible films have gained increasing relevance as a novel dosage form. Associated to their particular processing and multicomponent…
Increasing the Oral Bioavailability of Poorly Water-soluble Valsartan Using Non- ordered Mesoporous…
04. July 2016 Aim: To evaluate the use of mesoporous silica SYLOID® 244 FP to increase the dissolution rate of valsartan, antihypertensive poorly water soluble,…
50 years of Gattefossé Bulletins Techniques
04. July 2016
In 1966, Gattefossé pioneered the first event to exchange on galenical formulations with the institution of Les Journées Galéniques of Saint Remy de Provence. Throughout the years numerous subjects have…
On the Relationship of Inter-particle Cohesiveness and Bulk Powder Behavior: Flowability of…
04. July 2016 Abstract This study investigates the relationship between particle interactions dominated by the cohesive van der Waals force and powder flowability for…
Spheronization Mechanism of Pharmaceutical Material Crystals Processed by Extremely High Shearing…
04. July 2016 Abstract We aimed to elucidate the mechanism of the spheronization of pharmaceutical material crystals through extremely high shearing force using a…
TASTING CETIRIZINE-BASED MICROSPHERES WITH AN ELECTRONIC TONGUE
04. July 2016 Abstract Nowadays electronic tongues are used for the recognition of variety of samples, but most popular application area is pharmaceutical analysis,…
Influence of variation in molar ratio on co-amorphous drug-amino acid systems
04. July 2016 Abstract Molecular interactions were investigated within four different co-amorphous drug-amino acid systems, namely indomethacin−tryptophan (Ind−Trp),…
The effects of polar excipients transcutol and dexpanthenol on molecular mobility, permeability, and…
30. June 2016 Abstract In the development of transdermal and topical products it is important to understand how formulation ingredients interact with the molecular…
Modification of oral dosage forms for the older adult: an Irish prevalence study
30. June 2016 Abstract Age-related pharmacological changes complicate oral dosage form (ODF) suitability for older adults. The aim of this study was to investigate the…
Advanced Excipient Technology from Vitaldose EVA Excipient @ CRS annual Meeting
30. June 2016
VITALDOSE® EVA—AN EFFECTIVE DRUG DELIVERY TECHNOLOGY
Our custom controlled release ethylene vinyl acetate, VitalDose® EVA, is improving pharmaceutical drug delivery applications around the world. VitalDose…
Antiretroviral Therapy through Barriers: A ProminentRole for Nanotechnology in HIV-1 Eradication…
30. June 2016 Antiretroviral Therapy through Barriers: A ProminentRole for Nanotechnology in HIV-1 Eradication fromSanctuaries Abstract: In HIV-1 management, eradication of…
An Overview of Pharmaceutical Excipients: Safe or Not Safe?
27. June 2016 Abstract A medicine consists of 2 fundamental parts: the active pharmaceutical ingredient and the excipient. Most, if not all, medicines could not be made…
Background review for the excipient boric acid
27. June 2016 In the context of the revision of the guideline on ‘Excipients in the label and package leaflet of medicinal…
Background review for sodium laurilsulfate used as an excipient
27. June 2016 In the context of the revision of the guideline on ‘Excipients in the label and package leaflet of medicinal…
A REVIEW OF CURRENT REGULATORY MECHANISM FOR PHARMACEUTICAL EXCIPIENTS IN USA
27. June 2016 Abstract Pharmaceutical excipients contribute unique functionalities to formulations, thereby largely determining the drug products quality and influencing…
“European Pharmacopoeia: Tackling future challenges of the Quality of Medicines together”
27. June 2016
27-28 September 2016, Tallinn, Estonia
Tallinn, Estonia
Conference Programme
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pH Responsive polyurethane (core) and cellulose acetate phthalate (shell) electrospun fibers for…
25. June 2016 Abstract In this study we present the use of co-axial electrospinning to produce core-shell composite micro-/nano- fibers of Polyurethane (PU) and Cellulose…
New aspects of controlled release systems for local anaesthetics. A Review
25. June 2016 Abstract Pharmacological pain control and management applied in this medical area represent the gold goal for anaesthesia and intensive care units. One of…
Polymorphic behavior of isonicotinamide in cooling crystallization from various solvents
25. June 2016 Abstract In this work the nucleation of different polymorphs of isonicotinamide (INA) from different solvents has been studied. The metastable zone width of…
Using Population Pharmacokinetic and Pharmacodynamic Analyses of Entecavir in Pediatric Subjects to…
25. June 2016 Abstract Background Entecavir is an orally administered guanosine nucleoside analog with activity against hepatitis B virus (HBV) polymerase, which is…
Synthesis of surfactant-free hydroxypropyl methylcellulose nanogels for controlled release of…
25. June 2016 Abstract A facile controlled-release nanogels delivery system has been developed by using hydroxypropyl methylcellulose (HPMC) hybrid nanogels as…
Once-daily amoxicillin immediate- and extended-release bilayer tablets
Multilayer/bilayer tablets have been applied for the formulation of incompatible components for compound preparations, but more often they are used to modify drug release. The objective of this study was to explore the feasibility…
PHARMACOPOEIAL DISCUSSION GROUP ACHIEVEMENTS @ meeting hosted by EDQM inStrasbourg, France, 25-26…
25. June 2016 PHARMACOPOEIAL DISCUSSION GROUP ACHIEVEMENTS @ meeting hosted by EDQM inStrasbourg, France, 25-26 May 2016 The meeting of the Pharmacopoeial…
Improving the granule strength of roller-compacted ibuprofen sodium for hot-melt coating processing
25. June 2016
Abstract
Solvent-free hot-melt coating processing is a novel and cost-efficient approach to manufacturing taste-masked multiparticulate systems. However, most API powders are fine and cohesive and not…
Dow Announces Global Launch and Commercial Availability of ETHOCEL™ High Productivity
25. June 2016
A Solvent-Free Advanced Productivity Technology for Barrier Membrane Coatings
Philadelphia, PA: Tuesday, June 21, 2016
“The global commercial launch of ETHOCEL™ HP is an exciting development for our…