Comparison of in vitro screening methods for evaluating the effects of pharmaceutical excipients on membrane permeability
The effects of pharmaceutical excipients on intestinal drug absorption have been highlighted and careful excipient selection is required to develop biologically equivalent formulations. This study aimed to evaluate the effects of excipients on drug permeability and compare the characteristics of in vitro screening methods. Three in vitro models,…
Powder Compaction in relation to variation of excipient and application of QbD to link Formulation…
19. November 2016
Introduction
Manufacturing processes have not kept pace with inventions in the pharmaceutical industry. However, the Quality by design approach which integrates quality into every aspect of…
Oral Delivery of Insulin via Polyethylene Imine-based Nanoparticles for Colonic Release Allows…
18. May 2016 In this study, insulin-containing nanoparticles were loaded into pellet cores and orally administered to diabetic rats. Polyethylene imine-based nanoparticles,…
Drug Formulation, Solubility & Bioavailability Summit
18. May 2016
Drug Formulation, Solubility & Bioavailability Summit
30–31 MAY 2016 • NOVOTEL BARCELONA CITY • BARCELONA, SPAIN
Information & Registration
ASHLAND’s AQUARIUS™ PLANT SITE RECEIVES EXCiPACT GMP CERTIFICATION AS PHARMACEUTICAL EXCIPIENT…
Brussels, 17. May, 2016
EXCiPACT asbl is delighted to announce that Ashland’s Aquarius™ plant site has recently been awarded an EXCiPACT Certificate from SGS Belgium, one of EXCIPACT’s internationally-recognised Certification Bodies.
The…
Partially hydrolyzed polyvinyl alcohol as functional excipient in oral solid dosage forms prepared…
18. May 2016 Formulators are constantly looking for novel excipients which provide specific properties to a formulation and which (preferably) can be used for a broad range…
Effect of colloidal silica on rheological properties of common pharmaceutical excipients
16. May 2016 In pharmaceutical industry, the use of lubricants is mostly based on historical experiences or trial and error methods even these days. It may be demanding in…
A Novel MicroparticulateFormulation with Allicin In SituSynthesis
16. May 2016 A Novel MicroparticulateFormulation with Allicin In SituSynthesis The development of Garlic as a commercial antibiotic has come to a halt. Although its…
Compatibility study of paracetamol, chlorpheniramine maleate and phenylephrinehydrochloride in…
16. May 2016 Compatibility study of paracetamol, chlorpheniramine maleate and phenylephrinehydrochloride in physical mixtures Paracetamol (PAR), phenylephrine…
Effect of Hydrophobic Modification of Hydroxypropyl Methylcellulose on Silicone Oil Emulsions
16. May 2016 To study the effect of hydrophobic modification of the emulsifier on the relationship between emulsion stability and polymer emulsifier concentration, silicone…
PULSATILE DRUG DELIVERY SYSTEM: A REVIEW
15. May 2016 Pulsatile Drug Delivery Systems are gaining a lot of interest as they deliver the drug at the right place at the right time and in the right amount, thus…
Chronotherapeutic Drug Delivery System: A NovelApproach For Treatment Of Nocturnal Diseases.
15. May 2016 Chronotherapeutic Drug Delivery System: A NovelApproach For Treatment Of Nocturnal Diseases. All functions in human are highly organized in time as biological…
Overview on gastroretentive drug delivery systems for improving drug bioavailability
15. May 2016 In recent decades, many efforts have been made in order to improve drug bioavailability after oral administration. Gastroretentive drug delivery systems are a…
A Review on Transdermal Spray: Formulation Aspect
15. May 2016 Transdermal spray offers numerous advantages over the other conventional transdermal drug delivery forms such as gel, ointment and patches, in terms of its…
Formulation and Evaluation of Meclizine Hcl Orally Dispersible Tablets by using Natural Super…
13. May 2016 Formulation and Evaluation of Meclizine Hcl Orally Dispersible Tablets by using Natural Super Disintegrants The present study is on Meclizine HCL orally…
Tell us About Yourself and Win a $20 Giving Card
12. May 2016
We want to learn more about your role in the pharmaceutical excipient selection process in your organization. The first 250 respondents who complete our short survey will receive a $20 Global Giving gift card.…
IPEC-Americas Publishes Quality by Design Sampling Guide for Excipient Makers, Users, and…
International Pharmaceutical Excipients Council Of the Americas
PRESS RELEASE
Arlington, Virginia (2-May-2016)
IPEC-Americas Publishes Quality by Design Sampling Guide for Excipient Makers, Users, and
Distributors.…
Excipients Use in Parenteral and Lyophilized Formulation Development
11. May 2016 Excipients Use in Parenteral and Lyophilized Formulation Development Excipients are the integral part of pharmaceutical product development to achieve the…
Colours in Pharmaceutical Products
Reasons for the coloring of your pharmaceutical and nutraceutical products:
What is the impact of colored dosage forms in the pharmaceutical industry? Is it only about aesthetics or also patient safety and anti-counterfeiting?
Getting…
Impact of lipases on the protective effect of SEDDS for incorporated peptide drugs towards…
09. May 2016 Aim The aim of this study is the development of self-emulsifying drug delivery systems (SEDDS) differing in amounts of ester substructures and to evaluate…
Developing a miniaturized approach for formulation development using twin screw granulation
09. May 2016 The present research is focused on developing a novel, scaled-down approach based on the liquid droplet-powder bed interactions for the estimation of an optimal…
Towards Biopredictive Dissolution for Enteric Coated Dosage Forms
09. May 2016 The aim of this work was to develop a phosphate buffer-based dissolution method for enteric-coated formulations with improved biopredictivity for fasted…
A supersaturating delivery system of silibinin exhibiting high payload achieved by amorphous…
09. May 2016 The therapeutic potentials of silibinin – a phytochemical isolated from milk thistle plants – have not been fully realized due to its poor oral bioavailability…
Toward predicting tensile strength of pharmaceutical tablets by ultrasound measurement in continuous…
09. May 2016 An ultrasound measurement system was employed as a non-destructive method to evaluate its reliability in predicting the tensile strength of tablets and…
Importance and globalization status ofgood manufacturing practice (GMP) requirementsfor…
09. May 2016 Importance and globalization status ofgood manufacturing practice (GMP) requirementsfor pharmaceutical excipients Pharmaceutical excipients are no longer inert…
Excipients labelling
09. May 2016
The European Medicines Agency (EMA) publishes background documents on excipients for inclusion in the label and package leaflet of human medicines.
An excipient is a constituent of a medicine other than the …
Controlled release matrix tablets of glipizide: Influence of differentgrades of ethocel and…
08. May 2016 The aim of the current study was to formulate and evaluate glipizide controlled release matrix tablets by means of different grades of polymer Ethoceland…
Confusion between Two Amphotericin B Formulations Leading to a Paediatric Rehospitalisation
08. May 2016 Abstract A heavily immunosuppressed, 43-kg, 9-year-old patient was recovering from a bone marrow transplant. Primary prophylaxis against invasive…
Modulation of the wettability of excipients by surfactant and its impacts on the disintegration and…
08. May 2016 Objective: To investigate the modulation of the wettability of excipients by types of surfactants and its impacts on the disintegration of tablets and drug…
Challenges and Opportunities in Developing Up-to-Date USP–NF Excipient Monographs
08. May 2016 As the second part of this series, this article focuses on the harmonization activities related to excipients under the work plan of the Pharmacopeial…
Nanoparticles for Improved Delivery of Poorly Soluble Drugs
06. May 2016 Nanoparticle based drug products are of growing interest in the field of pharmaceutics. Enhancing saturation solubility and dissolution velocity by preparing…
FORMULATION AND IN-VITRO EVALUATION OF LACIDIPINEORAL DISINTEGRATING TABLETS: ENHANCEMENT…
06. May 2016 FORMULATION AND IN-VITRO EVALUATION OF LACIDIPINEORAL DISINTEGRATING TABLETS: ENHANCEMENT OFSOLUBILITY AND DISSOLUTION RATE The aim of present study was to…
Formulation, Development and Characterization of Floating Beads of Diltiazem Hydrochloride
06. May 2016 The main goal of any drug delivery system is to achieve desired concentration of the drug in blood or tissue, which is therapeutically effective and nontoxic…
How the EXCiPACT 3rd Party Certification Scheme is helping excipient suppliers with the increasing…
04. May 2016 How the EXCiPACT 3rd Party Certification Scheme is helping excipient suppliers with the increasing demands for audits – the User view…
GMP Aspects of Excipient Supply a risk based approach
04. May 2016 Kevin HughesRegulatory Affairs Manager, Colorcon LtdMaking…