Comparison of in vitro screening methods for evaluating the effects of pharmaceutical excipients on membrane permeability
The effects of pharmaceutical excipients on intestinal drug absorption have been highlighted and careful excipient selection is required to develop biologically equivalent formulations. This study aimed to evaluate the effects of excipients on drug permeability and compare the characteristics of in vitro screening methods. Three in vitro models,…
CompactCel® LUB – BIOGRUND’s one-step bindingagent
25. August 2016 CompactCel® LUB - BIOGRUND’s one-step bindingagent BIOGRUND’s one-step binding agent CompactCel® LUB combines the properties of a dry binder and lubricant.…
Comparative Pharmaceutical Study on Colon Targeted Micro-particles of Celecoxib: In-vitro- In-vivo…
24. April 2016
In order to target celecoxib which is a COX2 inhibitor, with potentials in the prevention and treatment of colitis and colon cancer, it was formulated as microparticles using solvent/evaporation method and…
An overview of Nano fibre membranes to deliver natural ingredient or extractfor targeted…
24. April 2016 An overview of Nano fibre membranes to deliver natural ingredient or extractfor targeted drug-delivery devices Herbal based medicines are used for the…
EXCiPACT 2-Day Training Course in Europe – Brussels, 15-16 November 2016
24. April 2016
The course is ideal for pharmaceutical excipient suppliers looking to implement and be certified using theEXCiPACT Scheme, using either the EXCiPACT GMP and/or GDP Standards with ISO 9001, or the…
Improved tabletability after a polymorphic transition of Delta mannitol during twin screw…
23. April 2016 In most formulations processed via continuous twin screw granulation microcrystalline cellulose (MCC) and/or lactose are used as excipients, but mannitol is…
50 years of oral lipid-based formulations: Provenance, progress and future perspectives
23. April 2016 50 years of oral lipid-based formulations: Provenance, progress and future perspectives Lipid based formulations (LBF) provide well proven opportunities…
Development of mucoadhesive drug delivery systems by precipitation of chitosan on drug-loaded…
23. April 2016 Multiparticulate dosage forms consist of small sub-units containing the drug and having the advantage of more uniform and predictable transit time, better…
Overview and Future Potential of Buccal Mucoadhesive Films as Drug Delivery Systems for Biologics
22. April 2016 The main route of administration for drug products is the oral route, yet biologics are initially developed as injectables due to their limited stability…
Electrostatic powder coating: Principles and pharmaceutical applications
21. April 2016 A majority of pharmaceutical powders are insulating materials that have a tendency to accumulate charge. This phenomenon has contributed to safety hazards and…
Application of ethyl cellulose, microcrystalline cellulose and octadecanol for wax based floating…
21. April 2016 The present study aimed to develop and optimize the wax based floating sustained-release dispersion pellets for a weakly acidic hydrophilic drug…
The extra-phosphate intestinal load from medications: is it a real concern?
21. April 2016 Reduction of intestinal load of phosphorus is important for the prevention and treatment of chronic kidney disease (CKD)-mineral and bone disorder (MBD).…
In-Line Monitoring of a Pharmaceutical Pan Coating Process by Optical Coherence Tomography
21. April 2016
In-Line Monitoring of a Pharmaceutical Pan Coating Process by Optical Coherence Tomography
This work demonstrates a new in-line measurement technique for monitoring the coating growth of randomly…
Scaling up a high shear granulation process to gain granules suitable to formulate orally …
21. April 2016 Scaling up a high shear granulation process to gain granules suitable to formulate orally disintegrating tablets In regard to line extensions or…
Montmorillonite-alginate microspheres as a delivery vehicle for oral extended release of Venlafaxine…
20. April 2016 Extended release of drugs is extremely essential for patients who require medicinal treatment round the clock. Depressed patients are one of such patients who…
Optimization of hot melt extrusion parameters for sphericity and hardness of polymeric face-cut…
20. April 2016 The aim of this study was to formulate face-cut, melt extruded pellets and to optimize hot melt process parameters to obtain maximized sphericity and hardness…
Innopharma Technology Launches Eyecon2™ Particle Size Analyser at POWTECH
DUBLIN, Ireland Apr, 19th 2016 – Innopharma Technology, today launches Eyecon2™, a non-product contact particle characteriser of powder based processes for the pharmaceutical, chemical and food industries at the POWTECH…
Application of ethyl cellulose, microcrystalline cellulose and octadecanol for wax based floating…
19. April 2016 The present study aimed to develop and optimize the wax based floating sustained-release dispersion pellets for a weakly acidic hydrophilic drug…
Formulation and Evaluation of Coprocessed Excipient for MouthDissolving Formulation
18. April 2016 In the present study an attempt has been made to evaluate Ocimum bascilium mucilage coprocessed with Mannitol as a novel super disintegrant. Coprocessed…
Formulation and evaluation of Gastro-retentive drug delivery system using Fenugreek gum as novel…
18. April 2016 The purpose of this study was to evaluate efficiency of fenugreek gum for developing gastro retentive floating tablets of Sumatriptan succinate when used…
Experimental Studies of the Ability of Pharmacopoeial Excipients to ReleasePharmacologically Active…
18. April 2016 Experimental Studies of the Ability of Pharmacopoeial Excipients to ReleasePharmacologically Active Substances when Developing Dental Dressing The…
Investigation on Drug Solubility Enhancement Using Deep Eutectic Solvents and Their Derivatives
18. April 2016 Deep eutectic solvent (DES) is a room temperature liquid typically formed by mixing two solid compounds, such as a quaternary ammonium salt (QAS) (e.g.…
Sex differences in excipient effects: Enhancement in ranitidine bioavailability in the presence of…
17. April 2016 Males and females respond differently to drugs: indeed, sex plays a crucial role in determining drug pharmacokinetics and pharmacodynamics. Excipients have…
Combination of Solvent Displacement and Wet Ball Milling Techniques for Size Reduction of Celecoxib
15. April 2016 Background: The objective of the present study was to investigate the combinative effect of ball milling and solvent displacement method on size reduction…
The 8th Annual Bioprocessing Summit
14. April 2016 Cambridge Healthtech Institute’s 4th Annual Overcoming Formulation Challenges for Biopharmaceutical Development Formulation and…
2016 annual workshop of the European network of paediatric research (Enpr-EMA) at the European…
14. April 2016
June 2- 3, 2016 European Medicines Agency, London, UK
The first day of the workshop is an open meeting to all stakeholders, including patient and parent organisations, network representatives,…
Polyelectrolyte Complexes Based on Chitosan and Natural Polymers
14. April 2016 For many years chitosan has been the subject of interest for its use in different medical fields due to its appealing properties such as biocompatibility,…
Toxic Phenol Ingredient in Vaccines
14. April 2016
Phenol, chemically known as carbolic acid, is a white, volatile crystal solid. It is a mildly acidic, water-soluble chemical that requires safe handling due its ability to cause chemical burns.…
Factors ınfluencing antibacterial activity of chitosan against Aeromonas hydrophila and…
14. April 2016
In this study, the effect of the incubation time, incubation temperature, pH, metal and sodium ions on the antibacterial activity of chitosan against food borne spoilage bacteria focused. Aeromonas hydrophila…
Containment-Lösung für den Labormaßstab
14. April 2016 Wie schrumpft man eine komplette Granulationslinie auf Labormaßstab? Containment inclusive? – Glatt hat gemeinsam mit dem Barrier-Hersteller Weiss…
MCC–mannitol mixtures after roll compaction/dry granulation: percolation thresholds for ribbon…
13. April 2016 In roll compaction, the specific compaction force, the gap width and the roll speed are the most important settings as they have a high impact in the products…
Usefulness and limitations of taste sensors in the evaluation of palatability and taste-masking in…
13. April 2016 The purpose of this review is to discuss the advantages and limitations of taste sensors in the evaluation of the taste of palatability of different oral…
Amino acids as co-amorphous excipients for tackling the poor aqueous solubility of valsartan
13. April 2016 Co-amorphization has recently been shown to be a promising approach for stabilizing amorphous drugs and improving the dissolution rate of poorly…
The function and performance of aqueous aerosol devices for inhalation therapy
13. April 2016 Objectives In this review paper, we explore the interaction between the functioning mechanism of different nebulizers and the physicochemical properties…