Comparison of in vitro screening methods for evaluating the effects of pharmaceutical excipients on membrane permeability
The effects of pharmaceutical excipients on intestinal drug absorption have been highlighted and careful excipient selection is required to develop biologically equivalent formulations. This study aimed to evaluate the effects of excipients on drug permeability and compare the characteristics of in vitro screening methods. Three in vitro models,…
Quince Seed Lyophilized Biopolymer as a Medicinal Remedy: Study of Mechanical Properties of the…
21. March 2016 Background: Quince seed mucilage biopolymer (QSMB), famous for ameliorating coughs and controlling asthma symptoms, has not been processed by scientific…
Formulation aspects in development of controlled porosity osmotic pump tablet
21. March 2016 The development of oral controlled release system has been a challenge to formulation scientist due to their inability to restrain and localize the system at…
A Tunable, Biodegradable, Thin-Film Polymer Device as a Long-Acting Implant Delivering Tenofovir…
21. March 2016 Purpose The effectiveness of Tenofovir based HIV pre-exposure prophylaxis (PrEP) is proven, but hinges on correct and consistent use. User compliance…
Rapid-Onset Sildenafil Sublingual Drug Delivery Systems: In Vitro Evaluation and In Vivo…
21. March 2016
The aim of the present study was to prepare sublingual delivery systems for sildenafil and evaluate its relative bioavailability after sublingual administration in rabbits to attain a rapid onset of action…
Custom-made solutions in Inhalation – DMV Lactose
21. March 2016 Custom-made solutions in Inhalation - DMV Lactose DFE Pharma is a leading specialist in production of excipients for virtually every kind of inhalation…
Influence of different types of commercially availablemicrocrystalline cellulose on degradation of…
21. March 2016 Influence of different types of commercially availablemicrocrystalline cellulose on degradation of perindopril erbumine and enalapril maleate in binary mixtures…
The Effect of Microcrystalline Cellulose Crystallinity on the Hydrophilic Property of Tablets and…
21. March 2016 Abstract. The crystal structures of active pharmaceutical ingredients and excipients should be strictly controlled because they influence pharmaceutical…
Electrochemical evaluation of antioxidant capacity in pharmaceutical antioxidant excipient of drugs…
20. March 2016 The aim of this study is to propose a new electrochemical method for the evaluation of the antioxidant capacity of the pharmaceutical antioxidant excipient in…
Modifying release characteristics from 3D printed drug-eluting products
20. March 2016
This work describes an approach to modify the release of active compound from a 3D printed model drug product geometry intended for flexible dosing and precision medication. The production of novel polylactic…
Safe and effective pharmacotherapy in infants and preschool children: importance of formulation…
20. March 2016 ABSTRACT Safe and effective paediatric pharmacotherapy requires careful evaluation of the type of drug substance, the necessary dose and the…
Mixed surfactant based (SNEDDS) self-nanoemulsifying drug delivery system presenting efavirenz for…
20. March 2016 This study aims to develop a self-nanoemulsifying drug delivery system (SNEDDS) based on non-ionic surfactant mixtures to improve the oral bioavailability of…
Comparison of metoprolol tartrate multiple-unit lipid matrix systems produced by different…
The aim of this study was to develop, evaluate and compare extended release mini-matrices based on metoprolol tartrate (MPT) and either glyceryl behenate (GB) or glyceryl palmitostearate (GPS). Mini-matrices were produced by three…
Development of novel flavored Eudragit® E films for feline minitablet coatings
18. March 2016 In this study, novel flavored taste masking film coating formulations were developed specifically for felines. Polymethacrylate copolymer (Eudragit® E) was…
The relevance of solid state propertiesof aminoglycoside antibiotics to drypowder dispersion in a…
18. March 2016 The relevance of solid state propertiesof aminoglycoside antibiotics to drypowder dispersion in a DPI Aminoglycosides are scarcely absorbed via the…
Formulation and Optimization of Immediate Release Tablet ofSitagliptin Phosphate using Response…
18. March 2016 Formulation and Optimization of Immediate Release Tablet ofSitagliptin Phosphate using Response Surface Methodology Abstract: The objective of this study was…
Particle Engineering across the Lengthscale
18. March 2016 TTC Technology Training Center Workshop07 – 09 JUNE 2016 in Weimar / Germany Information & Registration
Wirbelschicht: Wartung & Troubleshooting
18. March 2016 Wirbelschicht: Wartung & Troubleshooting TTC Technology Training Center Workshop 05 – 07 JULY 2016 in Binzen / Germany Information…
Guidance for Industry Question-Based Review for the Chemistry, Manufacturing, and Controls Technical…
18. March 2016
Draft Guidance This guidance is being distributed for comment purposes only. Submit comments on this draft guidance by the date provided in the Federal Register notice announcing the availability of the…
IPEC-Americas Insider
17. March 2016
IPEC-Americas Insider
IPEC-Americas International Task Force Now Forming
IPEC-Americas Call for volunteers for an International Task Force
IPEC-Americas is in the process of establishing…
Workshops at ExcipientFest 2016
16. March 2016
A Two-Day Educational Experience and Pharma Expo with in-depth Workshops and Education Sessions from Industry’s Top-Excipient Experts
Focused Technical and Regulatory Workshops
Overview and updates on…
Formulation of viscous Simethicone in to chewable tablets
16. March 2016 Simethicone is viscous, greyish-white, opalescent preparation used as anti foaming agent to prevent formation of gas in gastro intestinal tract. As per…
New systems capable of stimuli-controlled release of drugs
16. March 2016 The search for new medical strategies with high therapeutic efficiencies and reduced adverse side-effects remains a challenge for the scientific community.…
Gelatin composites for controlled release of actives
16. March 2016 During the 1950s the pharmaceutical market was flooded with oral products promising a prolonged release of actives. Since then a constantly…
7th Annual Global Drug Delivery & Formulation Summit
16. March 2016 7th Annual Global Drug Delivery & Formulation Summit 7th Annual Global Drug Delivery & Formulation Summit 23 - 25 May 2016…
Formulation and optimization of floating matrix tablets of clarithromycin using simplex lattice…
15. March 2016
Abstract: The purpose of the present study was to prepare floating matrix tablets of clarithromycin employing simplex lattice design. Hydroxypropyl methylcellulose (HPMC) and Ethyl Cellulose (EC) were used as…
Formulation and evaluation of Thiocolchicoside Topical Gel by using different method
15. March 2016
Thiocolchicoside used for the effective treatment of muscle spasm, cramps, musculoskeletal and neuromuscular disorders. It is available in market in the form of capsules and injection. The major problem…
Roll compaction/dry granulation: Suitability of different binders
15. March 2016 As dry granulation as a continuous process becomes steadily more important, the interest of different materials and their processing is growing. Binders are…
Patient centric formulations for paediatrics and geriatrics: Similarities and differences
15. March 2016 Paediatrics and geriatrics both represent highly heterogenous populations and require special consideration when developing appropriate dosage forms. This…
Pectin/HPMC dry powder coating formulations for colon specific targeting tablets of metronidazole
15. March 2016 The objective of this study was to develop a dry powder coating technique applied to colon targeting tablets containing metronidazole (MET) by using a pan…
Nano-confinement of acetaminophen into porous mannitol through adsorption method
15. March 2016 A new formulation has been developed successfully, which includes production of highly-porous mannitol particles with high surface areas through the spray…
Polymeric protective agents for nanoparticles in drug delivery and targeting
15. March 2016 Surface modification/functionalization of nanoparticles (NPs) using polymeric protective agents is an issue of great importance and actuality for drug…
Daicel FineChem Ltd. launches DiSPERZiSTA: State of the Art orally dispersible excipient system for…
15. March 2016
Daicel FineChem Ltd. is pleased to announce that it has launched DiSPERZiSTA: State of the Art orally dispersible excipient system for food supplement tablets.
DiSPERZiSTA is a co-processed…
Twin Screw Extruders as Continuous Mixers for Thermal Processing: a Technical and Historical…
14. March 2016 Developed approximately 100 years ago for natural rubber/plastics applications, processes via twin screw extrusion (TSE) now generate some of the most…
Formulation and Characterization of a Plasma Sterilized, Pharmaceutical Grade Chitosan Powder
14. March 2016 Chitosan has great potential as a pharmaceutical excipient. In this study, chitosan flake was micronized using cryo-ball and cryo-jet milling and subsequently…