Comparison of in vitro screening methods for evaluating the effects of pharmaceutical excipients on membrane permeability
The effects of pharmaceutical excipients on intestinal drug absorption have been highlighted and careful excipient selection is required to develop biologically equivalent formulations. This study aimed to evaluate the effects of excipients on drug permeability and compare the characteristics of in vitro screening methods. Three in vitro models,…
Buccal Transmucosal Delivery System of Enalapril for Improved Cardiac Drug Delivery: Preparation and…
07. February 2016 Buccal Transmucosal Delivery System of Enalapril for Improved Cardiac Drug Delivery: Preparation and Characterization Purpose: To prepare and…
GIORNATA DI STUDIO AFI – Eccipienti farmaceutici: le nuove regole
07. February 2016 Milano, 16 marzo 2016 Hotel Meliá Milano Via Masaccio, 19 - 20149 Milano More Information & Registration…
Excipients – wie viel GMP muss sein?
07. February 2016 Forum Seminar zu den kommenden Qualitätsanforderungen an Excipients 12. - 13.04.2016 - BONN / Germany More Information & Registration…
Development and in vivo evaluation of child-friendly lopinavir/ritonavir pediatric granules…
06. February 2016 The aim of this study was to develop a nanotechnology to formulate a fixed-dose combination of poorly water-soluble drugs in a children-friendly, flexible…
DESIGN AND EVALUATION OF ENTERIC COATED FORMULATIONS FOR AN ANTI-INFLAMMATORY DRUG BASED ON MODIFIED…
05. January 2016 E.E. Zien El-Deen*, M.M. Ghorab, S. Gad, H.A. YassinPharm.…
Evaluation of the ease of taking mini-tablets compared with other tablet formulations in healthy…
05. January 2016 “Mini-tablets” (MTs) are tablets of diameter ≤ 3 mm and have been widely studied and developed. However, reports comparing MTs with other tablet…
Structure of aqueous colloidal formulations used in coating and agglomeration processes: Mesoscale…
05. January 2016 In coating and agglomeration processes, the properties of the final product, such as solubility, size distribution, permeability and mechanical resistance,…
Recent Technological Advancements inMultiparticulate Formulations: The SmartDrug Delivery Systems
05. January 2016 Recent Technological Advancements inMultiparticulate Formulations: The SmartDrug Delivery Systems…
Assessment of Age-Related Changes in Pediatric Gastrointestinal Solubility
05. February 2016 PURPOSE: Compound solubility serves as a surrogate indicator of oral biopharmaceutical performance. Between infancy and adulthood, marked compositional…
Comilling of telmisartan with poly(vinyl alcohol) – An alkalanizer free green approach to ensure its…
05. February 2016 The aim of this study was to enhance the dissolution and bioavailability of telmisartan (TLM), a poorly water soluble drug by comilling approach. Physical…
Understanding and exploiting competing segregation mechanisms in horizontally rotated granular media
05. February 2016 C R K Windows-Yule1,2, B J Scheper1, A J van der Horn1, N…
Manufacturing Techniques and Surface Engineering of Polymer Based Nanoparticles for Targeted Drug…
05. February 2016
The evolution of polymer based nanoparticles as a drug delivery carrier via pharmaceutical nano/microencapsulation has greatly promoted the development of nano- and micro-medicine in the past few…
Development of a novel dry powder inhalation formulation for the delivery of rivastigmine hydrogen…
05. February 2016 The purpose of this study was to prepare engineered particles of rivastigmine hydrogen tartrate (RHT) and to characterize the physicochemical and…
Drug-Excipient Interaction of Methylphenidate with Glycerin in Methylphenidate Oral Solution and…
05. February 2016 Reactions between active drug substances and excipients are of interest in the drug formulation process should be checked for the interactions…
Excipients Use in Parenteral and Lyophilized Formulation Development
05. February 2016 Excipients are the integral part of pharmaceutical product development to achieve the desired product profile (stability and efficacy). This review…
PRACTICAL CONSIDERATIONS FOR LYOPHILIZED FORMULATION AND CYCLE DEVELOPMENT
05. February 2016 PRACTICAL CONSIDERATIONS FOR LYOPHILIZED FORMULATION AND CYCLE DEVELOPMENT PRACTICAL…
Assessing The Material, Compressional And Mechanical Properties Of Three Novel Excipients For Direct…
04. February 2016 Oyeniyi Y James*,1 and Gwarzo M. Sani2 .1. CSIR-IICB, Kolkata…
Application of general multilevel factorial design with formulation of fast disintegrating tablets…
04. February 2016 Despite the popularity of orally fast disintegrating tablets (FDTs), their formulation can sometimes be challenging, producing tablets with either poor…
Long-term tolerance of preservative-free eye drops containing macrogol hydroxystearate as an…
04. February 2016 Long-term tolerance of preservative-free eye drops containing macrogol hydroxystearate as an excipient Purpose This in vivo animal study was…
Lecithin, gelatin and hydrolyzed collagen orally disintegrating films: functional properties
04. February 2016 Orally disintegrating films (ODFs) can transport natural active compounds such as hydrolyzed collagen (HC) and ethanol extract of propolis (EEP). This…
IPEC Americas Excipient GMP Auditor Workshop
04. February 2016
Tuesday May 10 - Thursday May 12, 2016
Efficacy of a new once daily hydromorphone formulation in comparison with twice daily administration…
03. February 2016 Objective - Efficacy and safety of a novel multiple-unit hydromorphone once daily (HOD) was compared to an established hydromorphone twice daily (HTD)…
Design and optimization of disintegrating pellets of MCC by non-aqueous extrusion process using…
03. February 2016 The objective of the study was to design and optimize a disintegrating pellet formulation of microcrystalline cellulose by non-aqueous extrusion process…
Amorphous solid dispersions: Rational selection of a manufacturing process
03. February 2016 Amorphous products and particularly amorphous solid dispersions are currently one of the most exciting areas in the pharmaceutical field. This approach…
Current Challenges and Potential Opportunities for the Pharmaceutical Sciences to Make Global…
03. February 2016 Current Challenges and Potential Opportunities for the Pharmaceutical Sciences to Make Global Impact: An FIP Perspective The chairs of each of the 8…
Development and evaluation of floating microparticles for Levofloxacin as a gastroretentive carrier
03. February 2016 Development and evaluation of floating microparticles for Levofloxacin as a gastroretentive carrier Objective: In the present study an effort was…
Drug-Excipient Interaction Studies of Loperamide Loaded in Polsorbate 80 Liposomes
02. February 2016 Drug-Excipient Interaction Studies of Loperamide Loaded in Polsorbate 80 Liposomes Drug – delivery interaction studies were done for loperamide (Lp)…
Learning Lessons from Adverse Drug Reactions in Children
02. February 2016 Learning Lessons from Adverse Drug Reactions in Children Drug toxicity is, unfortunately, a significant problem in children both in the hospital and in…
Preparation of Bitter Taste-Masking Granules of Lafutidine for Orally Disintegrating Tablets using…
02. February 2016 Taste-masking granules were prepared by coating granules with a taste-masking layer prepared by combining the water-insoluble and -soluble…
EVALUATION OF FATTY ACIDS AS POTENTIAL MATRIX FORMERS FOR CONTROLLED RELEASE – A COMPARISON BETWEEN…
02. February 2016 The aim of this study is the development and characterization of multiparticulate dosage forms which release MPT, a β-blocker, at a controlled rate. In…
Pharmaceutical Applications of Native Starch in Conventional Drug Delivery
01. February 2016 Starch is a naturally occurring polymer that is present in many green plants. Its nontoxic and nonirritant properties as well as low costs, ease of…
Polymeric Amorphous Solid Dispersions: A Review of Amorphization, Crystallization, Stabilization,…
01. February 2016 Poor water solubility of many drugs has emerged as one of the major challenges in the pharmaceutical world. Polymer-based amorphous solid dispersions have…
Drop forming as a basis for a scaling up of the in situ coating process
01. February 2016 Cutting the costs of tablet manufacture is one of the many advantages melt crystallization offers compared to conventional tableting procedure as a…