Comparison of in vitro screening methods for evaluating the effects of pharmaceutical excipients on membrane permeability
The effects of pharmaceutical excipients on intestinal drug absorption have been highlighted and careful excipient selection is required to develop biologically equivalent formulations. This study aimed to evaluate the effects of excipients on drug permeability and compare the characteristics of in vitro screening methods. Three in vitro models,…
Micropellets: A promising strategy for controlled release of lansoprazole
01. February 2016 We aimed to develop a suitable micropellet delivery system for Lansoprazole, a highly potent proton pump inhibitor and acid-unstable physiologically…
L-Cystine-Crosslinked Polypeptide Nanogel as aReduction-Responsive Excipient for Prostate Cancer…
30. January 2016 Smart polymer nanogel-assisted drug delivery systems have attracted more and more attention in cancer chemotherapy because of their well-defined…
PEG codes used as anti-counterfeit marker in pharma
30. January 2016 Researchers in Germany have developed an on-dose marker technology based on polyethylene glycols (PEGs), a commonly used pharma excipient.…
Physicochemical and Excipient Characteristics of a Polymer Isolated from the Seeds of…
30. January 2016 This study was aimed at isolating, characterizing and evaluating the excipient functionalities of a polymer from watermelon seeds. After…
Excipient Industry’s Leading Expo and Conference for Regulatory, Science and Supply Chain…
30. January 2016
April 25 - 27, 2016
Renaissance Harborplace Hotel, Baltimore - MD
ExcipientFest attracts Pharmaceutical Scientists from the Americas and around the world to a unique two day forum…
Drug-Excipient Interactions: Case Studies and Overview of Drug Degradation Pathways
29. January 2016 The objective of the current research article is to provide a comprehensive review of excipients impact on the stability of the drug product and their…
Method Development and Validation for Fingolimod by HPLC/UV in Immediate-Release Oral Capsule and…
29. January 2016 Abstract A simple, selective, linear, precise, and accurate RP-HPLC method was developed and validated for the Quantitation of Fingolimod…
Formulation, Development and Evaluation of Meclozine Hydrochloride Microspheres
28. January 2016 Microspheres of meclozine hydrochloride (MCZ HCl) were formulated in order to prolong the residence time at the absorption site by intimate contact…
The influence of hydrophylic polymers on the release rate of calcium dobesilate in hydrogel…
28. January 2016
A shortage of available experimental data exists in the available bibliography on the release rate of calcium dobesilate (CD) from hydrogel formulations. Thus, the aim of the study was to evaluate the…
Oral drug dosage forms administered to hospitalized children: Analysis of 117,665 oral…
28. January 2016 Selecting the most appropriate dosage form, that ensures safe administration and adherence of medications, is a major issue for children. Marketed drugs,…
Amorphous Solid Dispersions or Prodrugs: Complementary Strategies to Increase Drug Absorption
28. January 2016 Maximizing oral bioavailability of drug candidates represents a challenge in the pharmaceutical industry. In recent years, there has been an increase…
Tablet/Capsule Size Variation Among the Most Commonly Prescribed Medications for Children in the…
28. January 2016 Children are frequently asked to take tablets and capsules of different sizes and shapes to manage acute and chronic medical conditions. Medication size is…
10th World Meeting on Pharmaceutics, Biopharmaceutics and Pharmaceutical Technology – Program
27. January 2016 The 10th World Meeting on Pharmaceutics, Biopharmaceutics and…
Mucoadhesive therapeutic compositions: a patent review (2011-2014)
27. January 2016 With the introduction of mucoadhesion in 1980, pharmaceutical researchers have gained interest in mucoadhesive compositions. This interest has led to the…
Comparative Study of Sustained Release Potential of a Newly Isolated Senna tora Seed Galactomannan…
27. January 2016 Pawar and Lalitha, J Bioequiv Availab 2016,…
Selected excipients and surfactants in oral solid dosage form withextract of Phaseoli pericarpium…
27. January 2016 ZBIGNIEW MARCZYŃSKI*, KATARZYNA KOWALCZYKIEWICZ,…
A critical review of algal biomass: A versatile platform of bio-based polyesters from renewable…
27. January 2016 Algal biomass is an excellent renewable resource for the production of polymers and other products due to their higher growth rate, high photosynthetic…
Taste Masking: A Novel Approach for Bitter and Obnoxious Drugs
26. January 2016 Aditi Tripathi*,Dipika Parmar,Dr. Upendra Patel,Ghanshyam…
TASTE MASKING OF PEADIATRIC FORMULATION: A REVIEW ON TECHNOLOGIES, RECENT TRENDS AND REGULATORY…
26. January 2016 JIJO ABRAHAM*, FLOWERLET MATHEWDepartment of Pharmaceutics,…
Recent advances in co-amorphous drug formulations
26. January 2016 Co-amorphous drug delivery systems have recently gained considerable interest in the pharmaceutical field because of their potential to improve oral…
The effect of mucoadhesive excipient on the nasal retention time of and the antibody responses…
25. January 2016 Recently, we reported that intranasal vaccination of humans with whole inactivated influenza vaccine in the absence of mucosal adjuvant induced neutralizing…
Making Pharmaceuticals – Birmingham 26-27 April 2016
25. January 2016 The only dedicated FREE TO ATTEND event in the UK that addresses the detailed and complex issues associated with sourcing, manufacturing,…
Preparation of multiparticulate systems for oral delivery of a micronized or nanosized poorly…
25. January 2016 The purpose of the present work was to prepare multiparticulate drug delivery systems for oral administration of a poorly soluble drug such as…
Evaluation of powder, solution and suspension layering for the preparation of enteric coated pellets
25. January 2016 Gastro-resistant pellets were prepared by use of three different drug loading techniques (powder layering, solution layering and suspension layering) and…
Formulation by Design Approach for FizzyGranules Using Statistical OptimizationMethodologies
24. January 2016 Formulation by Design Approach for FizzyGranules Using Statistical OptimizationMethodologies…
Polyethylene Glycol-Polyvinyl Alcohol Graft Copolymer: A Peroxide-Free Binder
24. January 2016 Original Link Print Excipients…
Solubility Concerns: API and Excipient Solutions
24. January 2016 Original Link Excipients Solubility Concerns: API and…
Quality by design case study 1: Design of 5-fluorouracil loaded lipid nanoparticles by the W/O/W…
23. January 2016 With Quality by Design (QbD), a systematic approach involving design and development of all production processes to achieve the final product with a…
Effect of cyclodextrin concentration on the oral bioavailability of danazol and cinnarizine in rats
23. January 2016 Cyclodextrins (CDs) are frequently used as an excipient to enhance the intestinal drug absorption of compounds with a low aqueous solubility. However, there…
Pluronic/gelatin composites for controlled release of actives
23. January 2016 This paper describes the preparation and the release properties of composite materials based on Pluronic F127 and gelatin hydrogels, which could be of…
Effect of Hydrophobic Inclusions on Polymer Swelling Kinetics Studied by Magnetic Resonance Imaging
22. January 2016 The rate of drug release from polymer matrix-based sustained release formulations is often controlled by the thickness of a gel layer that forms upon…