A Novel Approach of Formulation & Evaluation of Tablet in Capsule Device for GI Protection Pain Management
Abstract
This research article presents a novel approach in the formulation and evaluation of a tablet in capsule device aimed at providing GI protection and effective pain management. Key aspects include the development of Aceclofenac Extended-Release tablets and Misoprostol Immediate Release tablets, enclosed in a hard gelatin capsule. The study…
TTC – Technology Training Center Program 2016
26. December 2015
TTC Technology Training Center Program 2016
TTC has been created on direct request from the industry with respect to organize specialized workshops on processing disciplines, such as granulation,…
Micronization, characterization and in-vitro dissolution of shellac from PGSS supercritical CO2…
25. December 2015
The purpose of this investigation was to determine whether shellac, a naturally occurring material with enteric properties, could be processed in supercritical CO2 (sc-CO2) using the Particles…
Spray drying formulation of amorphous solid dispersions
25. December 2015 Spray drying is a well-established manufacturing technique which can be used to formulate amorphous solid dispersions (ASDs) which is an effective…
DRUG EXCIPIENT COMPATIBILITY SCREENING OF FEXOFENADINE HYDROCHLORIDE FOR ORALLY DISINTEGRATING…
24. December 2015 Mathivanan N and Chandrasekhara Rao G. / International Journal…
Formulation and Design of Multiunit Particulate System (MUPS) Tablet of Pantoprazole by QbD : Study…
24. December 2015 Formulation and Design of Multiunit Particulate System(MUPS) Tablet of Pantoprazole by QbD : Study Effect ofFormulation Variables on Tablet Characteristics…
Formulation and Evaluation of Mucoadhesive Thermosensitive in situ Gel of Tenofovir Disoproxil…
24. December 2015
Pre-exposure prophylaxis (PrEP) is one of the best preventive strategies in protection against HIV/AIDS. The present research approach is development of novel topical thermosensitive mucoadhesive in situ gel…
To study the influence of different grades of Ethylcellulose ether derivative polymer Ethocel® and…
23. December 2015 To study the influence of different grades of Ethylcellulose etherderivative polymer Ethocel® and co-excipient on drug releaseprofile of controlled release ma…
Preparation of Fenofibrate Dry Emulsion and Dry Suspension Using Octenyl Succinic Anhydride Starch…
23. December 2015 Purpose of this study was to investigate the ability of octenyl succinic anhydride (OSA) starch as emulsifier and solid carrier in dry emulsion (DE) and…
Fabrication of a Novel DeviceContaining Famotidine forGastro Retentive Delivery UsingCarbohydrate…
23. December 2015 Fabrication of a Novel DeviceContaining Famotidine forGastro Retentive Delivery UsingCarbohydrate Polymers…
Recent advancements in mucoadhesive floating drug delivery systems: A mini-review
22. December 2015 Over the past few decades, extensive research has been carried out to develop a gastroretentive dosage form (GRDF). This type of dosage form can improve…
Design, characterization and in vitro evaluation of a novel thiolated polymer: preactivated…
22. December 2015 To design a novel preactived carboxymethyl cellulose derivative. Methods: First, carboxymethyl cellulose (CMC) was chemically modified by amide bond…
Cyclodextrin based ternary system of modafinil: Effect of trimethyl chitosan and…
22. December 2015 Modafinil is an approved drug for the treatment of narcolepsy and have a strong market presence in many countries. The drug is widely consumed for…
The impact of hot-melt extrusion on the tableting behaviour of polyvinyl alcohol
21. December 2015 There is evidence that processing techniques like hot-melt extrusion (HME) could alter the mechanical properties of pharmaceuticals, which may impede…
Recent Advances in Microspheres Technology for Drug Delivery
20. December 2015 Navneet Kumar Verma1*, Gulzar Alam1, D.K.Vishwakarma1,…
Formulation design and evaluation of amorphous ABT-102 nanoparticles
20. December 2015 Amorphous nanoparticles are able to enhance the kinetic solubility and concomitant dissolution rates of BCS class II and BCS class II/IV molecules due to…
3D Printing Technology in Pharmaceutical Drug Delivery: Prospects andChallenges
19. December 2015 3D Printing Technology in Pharmaceutical Drug Delivery: Prospects and Challenges…
Development of Pellets for Oral Lysozyme Delivery by Using a Quality by Design Approach
19. December 2015 The concept of Quality by Design is of increasing importance in the pharmaceutical industry, especially in the development of biotechnologically produced…
Ethylcellulose film coating of guaifenesin-loaded pellets: A comprehensive evaluation of the…
19. December 2015 The aim of the research was to investigate the complete process of pellet production in a Wurster fluidized bed coater in order to determine the main…
Extended Release Orally Disintegrating Dosage Forms are Potential Techniques to Deliver and Maintain…
19. December 2015 Extended Release Orally Disintegrating Dosage Forms are Potential Techniques to Deliver and Maintain the Therapeutic Ranges of Plasma Drug Concentrations…
Cyclodextrins in pharmaceutical formulations II: solubilization, binding constant, and complexation…
18. December 2015 Cyclodextrins are cyclic oligosaccharides that have been recognized as pharmaceutical adjuvants for the past 20 years. The molecular structure of these…
Role of Polymeric Excipients in the Stabilization of Olanzapine when Exposed to Aqueous Environments
18. December 2015 Maria Paisana 1, Martin Wahl 2 and João Pinto 1,*1…
Methodology of oral formulation selection in the pharmaceutical industry
18. December 2015 Pharmaceutical formulations have to fulfil various requirements with respect to their intended use, either in the development phase or as a commercial…
Evaluation of the versatile character of a nanoemulsion formulation
18. December 2015 The formulate-ability of six model active pharmaceutical ingredients (API), with different physico-chemical profiles, in a nanoemulsion designed to be…
Long-Term Sustained Ciprofloxacin Release from PMMA and Hydrophilic Polymer Blended Nanofibers
17. December 2015 Nanofibers represent an attractive novel drug delivery system for prolonged and controlled release. However, sustained release of hydrophilic drugs, like…
Disintegration of nano-embedded microparticles after deposition on mucus: a mechanistic study
17. December 2015 The conversion of colloidal drug carriers/polymeric nanoparticles into dry microparticulate powders (e.g. by spray-drying) is a prominent approach to…
A novel formulation for solubility and content uniformity enhancement of poorly water-soluble drugs…
17. December 2015 The present study investigates the enhancement of the dissolution rates for poorly-water soluble drugs by a new adsorption method. The results show that…
Tween 20 increases intestinal transport of doxorubicin in vitro but not in vivo
17. December 2015 The chemotherapeutic drug substance doxorubicin has been reported to be a substrate of P-gp, which induces a barrier for oral administration and leads to a…
Impact of formulation and process variables on solid-state stability of theophylline in controlled…
17. December 2015 Understanding the impact of pharmaceutical processing, formulation excipients and their interactions on the solid-state transitions of pharmaceutical…
IPEC China: The first 2-day EXCiPACT™ Public Training Course in China
16. December 2015 IPEC China: The first 2-day EXCiPACT™ Public Training Course in China 14th and 15thJanuary, 2016 in Shanghai More…
β-Cyclodextrins as a Solubilization Tool for Insoluble APIs – White Paper Roquette
16. December 2015 The use of β-CDs can help to overcome one of the main challenges in drug delivery: guaranteeing the bioavailability of APIs, especially when they are…
Development of a new formulation for direct compression of a natural product
15. December 2015
Melissa Maltais1*, Ricardo Vargas1† and Therese DiPaolo2†
*Correspondence: Melissa Maltais [email protected]
1. Department of Pharmaceutics and Analytics, Purdue Pharma, 575…
Excipient risk assessment becomes more stringent
15. December 2015
The new EU guideline 2015/C 95/02 calls pharma companies to run by March 2016 a detailed analysis of the impact and risks expected by the use of the excipients in product development and manufacturing. We…
PEGylated Nanoparticles Obtained through Emulsion Polymerization as Paclitaxel Carriers
15. December 2015 Polymer nanoparticles (NPs) represent a promising way to deliver poorly water-soluble anticancer drugs without the use of unwanted excipients, whose…
Preformulation and characterization of a Lidocaine Hydrochloride and Dexamethasone Sodium Phosphate…
15. December 2015 The search for new formulations of anaesthetic agents that allow a localized administration and provide a prolonged effect is of great interest in the…