Low drug load, high retention mometasone furoate cream with polyglyceryl − 3 oleate as a chemical enhancer: Formulation development, in vivo and in vitro evaluation and molecular mechanisms
Abstract
The study aimed to create a low loading, high retention, easier to apply O/W mometasone furoate (MF) cream using a chemical enhancer (CE) approach to provide more options for patients with atopic dermatitis (AD) and to investigate molecular mechanisms of its increased release and retention. A Box-Behnken design determined the optimal…
Pellets and Micropellets for multiparticulate oral dosage forms – TTC Workshop
27. October 2015 Highlights • Βacterial Cellulose (BC) can adsorbed onto the WPI-coated emulsions and form a second layer. • Stable emulsions were obtained…
Practical, regulatory and clinical considerations for development of inhalation drug products
27. October 2015 The formulation and device collectively constitute an inhalation…
Development of novel multifunction directly compressible co-processed excipient by melt granulation…
27. October 2015
Introduction:
The objective of the present investigation was to develop a novel multifunctional directly compressible co-processed excipient consisting of dibasic calcium phosphate anhydrous, polyethylene glycol…
Designing, Development and Formulation of Mouth Disintegrating Telmisartan Tablet with Extended…
27. October 2015 Akram MA, Nazir T, Sarfraz M, Nazir SR (2015)…
EMD Millipore Introduces Parteck® SRP 80 Excipient for Sustained-Release Oral Solid Dose…
27. October 2015 BILLERICA, Mass., Oct. 26, 2015 /PRNewswire/ -- EMD Millipore, the Life Science business of Merck KGaA of Darmstadt, Germany, today introduced Parteck® SRP…
Application of the central composite design to optimizing the calcium carbonate-HPMC co-processed…
27. October 2015 To develop a novel co-processed tablet excipient based on calcium carbonate and hydroxypropyl methylcellulose (HPMC), the central composite design-response…
Mitigating unwanted amorphisation: A screening method for the selection of suitable excipients
26. October 2015 Co-processing an active pharmaceutical ingredient (API) with a low Tg excipient has been previously reported to be an effective strategy for preventing drug…
Applying a novel electrostatic dry powder coating technology to pellets
26. October 2015 The present study aimed to apply a novel dry powder technology to coat pellets with different coating materials grounded into fine powders. Piroxicam, a…
SPHERICAL CRYSTALLISATION: A REVOLUTION IN THE FIELD OF PARTICLE ENGINEERING
26. October 2015 BHAWANA KESHWANI*1, MANISH JAIMINI1, DIVYANSHU SHARMA21Jaipur…
Polymorph Impact on the Bioavailability and Stability of Poorly Soluble Drugs
26. October 2015 Roberta Censi and Piera Di Martino * School of Pharmacy,…
Pellets and Micropellets for multiparticulate oral dosage forms – TTC Workshop
23. October 2015
TTC Technology Training Center Workshop
24 - 26 November 2015 in Binzen, Germany
This workshop aims to elaborate the advantages and drawbacks of the individual techniques, focusing on the…
Extraction and physicochemical characterization of a potential multifunctional pharma-excipient from…
22. October 2015 Emmanuel O. Olorunsola, Olubunmi J. Olayemi, Stephen O.…
Research on Preparation and Properties of Coated Polyether Silicone Microencapsulation Based on…
22. October 2015 Shuiyun Ren, Huangjun Huang, Jianwei Hu & Hongjing…
Nanostructured lipid carriers: An emerging platform for improving oral bioavailability of lipophilic…
21. October 2015
Nowadays exploration of novel lipid-based formulations is akin to a magnet for researchers worldwide for improving the in vivo performance of highly lipophilic drugs. Over the last few years, new…
Preparation, Characterization and Evaluation of Elvitegravir-Loaded Solid Lipid Nanoparticles…
20. October 2015 Preparation, Characterization and Evaluation of Elvitegravir-Loaded Solid Lipid…
Investigation of new formulations of acrylic bone cement containing antibiotics – Thesis
20. October 2015 Investigation of New Formulations of Acrylic Bone Cement Containing Antibiotics…
Hydroxypropylmethyl cellulose-based sponges loaded self-microemulsifying curcumin: Preparation,…
20. October 2015 Novel hydroxypropylmethyl cellulose (HPMC)-based sponges containing self-microemulsifying curcumin (SME-Cur) were prepared by a freeze drying method using…
One-step continuous extrusion process for the manufacturing of solid dispersions
20. October 2015 56065e6d08aeb5718ff29ce9.pdf…
Microencapsulation of Fish Oil Using Hydroxypropyl Methylcellulose As a Carrier Material by Spray…
20. October 2015 Spray drying is an important method in the food industry for the production of encapsulated oil to improve the handling and flow properties of the powder.…
Pay-as-you-go or unlimited access? EMD ups its risk assessment service
20. October 2015 By Dan Stanton+, 20-Oct-2015 EMD Millipore will offer drugmakers two-years of unlimited access to its suite of raw materials dossiers for 20,000€ as part…
IX Internacional Forum on Advances in Pharmaceutical Technology – CISDEM
20. October 2015
November 5-6, 2015
Santiago de Compostela, Spain
2016 IPEC Europe Excipients Forum – 4 February 2016, Nice (FR)
19. October 2015
The 2016 event will address topics such as risk assessment for excipients, ICH Q3D, EXCiPACT Certifying Body experience, QbD and also the use of excipients in paediatrics.
…
Excipient Variability: A Fuss or a Big Deal?
19. October 2015
BY AJIT S. NARANG, MIKE TOBYN, AND ROBERT A. REED
Excipient variability has been studied in areas such as particle characteristics, cross-linking, or reactive impurities with the goals of (a) identifying…
Improved Process Understanding of Fluid Bed Granulation and Coating using Current PAT Solutions…
19. October 2015 GLATT AND INNOPHARMA LABS WOULD LIKE TO INVITE YOU TO OUR INDUSTRY WORKSHOP - November 11th 2015 Improved Process Understanding of Fluid…
FORMULATION, OPTIMIZATION AND EVALUATION OF FAST DISSOLVING ORAL FILM OF DOMPERIDONE
18. October 2015 441.pdf…
Carboxymethyl starch mucoadhesive microspheres as gastroretentive dosage form
18. October 2015 Carboxymethyl starch microspheres (CMS-MS) were produced from carboxymethyl starch powder (CMS-P) with a degree of substitution (DS) from 0.1 to 1.5 in…
Effect of Calcium Chloride and Barium Chloride on Release Behavior of Babul (Acacia nilotica) Gum…
18. October 2015 10.pdf…
Dow’s New Excipient Is Designed for Hot-Melt Extrusion
18. October 2015 Oct 15, 2015 By Pharmaceutical Technology Editors At CPhI Worldwide 2015, The Dow Chemical Company announced the global commercial availability of…
Double-layer Tablets of Lornoxicam: Validation of Quantification Method, In vitro Dissolution and…
06. October 2015 Ümit Gönüllü*, Pınar Gürpınar and Melike ÜnerIstanbul…
PharmaLunch SAPhW “Mesoporous Silica in the field of Drug Delivery”
09. October 2015
Fred Monsuur
Global Excipients Development Manager
Grace Materials Technologies
Basel, November 27, 2015
Excipient variability: A very big deal sometimes
09. October 2015
"Making mini-formulations of excipients in the lab and assessing their processability and stability cannot capture the full potential for variability. It’s better to map an API’s…
The importance of binder moisture content in Metformin HCL high-dose formulations prepared by moist…
08. October 2015 The aim of this study was to evaluate binders to improve the flowability of granulates and compactibility of Metformin HCL (Met) using the moist aqueous…
Key interactions of surfactants in therapeutic protein formulations: A review
08. October 2015 Key interactions of surfactants in therapeutic protein formulations: A review Proteins as amphiphilic, surface-active macromolecules, demonstrate…
Nisso and Mutchler Announce Partnership for Supply of Excipients to the Pharmaceutical Industry
08. October 2015
Nisso America, Inc. and Mutchler Pharmaceutical Ingredients, Inc. announced their co-marketing and distribution partnership for Nisso HPC (hydroxypropyl cellulose), a highly efficient excipient…