Low drug load, high retention mometasone furoate cream with polyglyceryl − 3 oleate as a chemical enhancer: Formulation development, in vivo and in vitro evaluation and molecular mechanisms
Abstract
The study aimed to create a low loading, high retention, easier to apply O/W mometasone furoate (MF) cream using a chemical enhancer (CE) approach to provide more options for patients with atopic dermatitis (AD) and to investigate molecular mechanisms of its increased release and retention. A Box-Behnken design determined the optimal…
An updated review on pulsatile drug delivery system – Article
19. September 2015 An updated review on pulsatile drug delivery system…
Preparation and evaluation of mucoadhasive microspheres of Propranolol HCl for nasal delivery…
19. September 2015 Preparation and evaluation of mucoadhasive microspheres of Propranolol HCl for nasal…
Advanced formulations for improving therapies with anti-inflammatory or anaesthetic drugs: a review
19. September 2015 The development of new more effective therapeutic treatments for pain relief is essential for enhancing the patient quality of life and safety and…
Inhalation Hard Capsules – Evaluation of the Performance of Hypromellose Capsules for Dry Powder…
19. September 2015 Inhalation Hard Capsules – Evaluation of the Performance of Hypromellose Capsules for Dry…
Influence of excipients on solvent-mediated hydrate formation of piroxicam studied by dynamic…
19. September 2015 Hydrate formation of pharmaceutical compounds can affect critical drug properties such as solubility and dissolution. There is early on in development a…
Validation of the IntelliCap®system as a tool to evaluate extended release profiles in human GI…
19. September 2015 A clinical studywas conducted to validate the in vivo drug release performance of IntelliCap® CR capsules.12 healthy, male volunteers were administered…
Techniques used to Enhance Bioavailability of BCS Class II Drugs: AReview
19. September 2015 Techniques used to Enhance Bioavailability of BCS Class II Drugs: A Review…
Respirable amikacin dry powders for inhalation by a Quality by Design procedure
19. September 2015 32.Belotti.pdf…
Compaction behavior and deformation mechanism of directly compressible textured mannitol in a rotary…
19. September 2015 Textured mannitol powder is widely used as a pharmaceutical excipient for tablet compaction. In order to choose the right tableting parameters, it is…
Development of self emulsifying lipid formulations of BCS class II drugs with low to medium…
19. September 2015 Lipid-based formulations can be effective drug delivery systems for poorly water-soluble chemical entities, provided they are designed with careful…
Improved Process Understanding of Fluid Bed Granulation and Coating using Current PAT Solutions…
18. September 2015 October 7, 2015 at Griffith College Dublin More Information & Registration
Sensory Evaluation of ISOMALT, MANNITOL and SUCROSE with Respect to the Manufacture of…
18. September 2015 Pharma_poster_Sensorik_A0_portrait.pdf…
AN INVESTIGATION INTO TASTE MASKING OF A MICRONIZEDPARACETAMOL USING AQUACOAT® ECD APPLIED VIA…
INTRODUCTION AND PURPOSE
Taste masking is a very important step in the development of paediatric medications such as oral suspensions and tablets for products with APIs that are bitter or unpalatable. In this study, taste…
“Highly Potent Drug Products in the Pharmaceutical Industry” APV Conference – 23.11. – …
17. September 2015
“Highly Potent Drug Products in the Pharmaceutical Industry” APV Conference - 23.11. - 24.11.2015 | Berlin, Germany
APV
The conference provides not only a broad overview on all relevant…
Sex matters: Differing effects of excipients on drug bioavailability in men and women –…
17. September 2015 It is known that some drugs behave differently in men and women; indeed, gender plays a crucial role in pharmacokinetics, pharmacodynamics and drug…
Application of a Multicomponent Lentinus tuber regium Based Co-Processed Excipient (fizlent) as a…
08. September 2015 Application of a Multicomponent Lentinus tuber regium Based Co-Processed Excipient…
Excipients in Oral Antihistamines Can Perpetuate Allergic Contact Dermatitis – Abstract
08. September 2015 Propylene glycol is a well-documented causative agent of allergic contact dermatitis (ACD). It is also reported to cause systemic dermatitis after…
Industry Responds to FDA Metrics Program
08. September 2015
After nearly three years of workshops, white papers, and pilot tests, one might expect some agreement between FDA and manufacturers of drugs and biologics on how to measure the quality and reliability of…
Evaluation of Binders and Process Factors in Continuous Twinscrew Granulation – Technical…
08. September 2015 This study explored a high dose formulation with model drug aceta-minophen and investigated the formulation (different binder types) and process factors…
Gelatin-free Softgels: Development and Optimization of Polysaccharide Capsule Shell Systems Suitable…
08. September 2015 Purpose To develop polysaccharide-based capsule shell formulations in combination with elevated temperature filling processes, suitable for the…
SAPhW PharmaLunch – “Batch goes Conti – Ein Überblick kontinuierlicher…
08. September 2015 SAPhW PharmaLunch - "Batch goes Conti - Ein Überblick kontinuierlicher Herstellprozesse in OSD" - September 25, 2015 in Basel…
Effect of hydrophilic additives on the dissolution and pharmacokinetic properties of…
15. September 2015 Hot-melt extrusion technology has been widely reported for producing amorphous solid dispersions of poorly water-soluble compounds. A number of studies…
Current Strategies for Sustaining Drug Release from Electrospun Nanofibers – Abstract
15. September 2015 Electrospun drug-eluting fibers are emerging as a novel dosage form for multipurpose prevention against sexually transmitted infections, including HIV,…
Foam extrusion of LDPE with solid phase CO2 as blowing agent – Abstract
15. September 2015 Physical foaming usually requires special metering equipment to inject the blowing agent at high pressures. In this study, low density polyethylene (LDPE)…
Dissolution enhancement of glimepiride dispersion using glyceryl monostearate and β-cyclodextrin as…
15. September 2015 Dissolution enhancement of glimepiride dispersion using glyceryl monostearate and β-cyclodextrin as carrier - Article…
Deconstructing HPMCAS: Excipient Design to Tailor Polymer–Drug Interactions for Oral Drug Delivery…
15. September 2015 Spray-dried dispersions (SDDs) are fascinating polymer–drug mixtures that exploit the amorphous state of a drug to dramatically elevate its apparent…
Effect of HPMC and ethyl cellulose polymeric granules and its combinations in press coated tablets…
15. September 2015 16865.pdf…
QUALITY-BY-DESIGN RISK ASSESSMENT OF TOPICAL FORMULATION VARIABILITY – Poster
15. September 2015 QUALITY-BY-DESIGN RISK ASSESSMENT OF TOPICAL FORMULATION VARIABILITY…
Drug-Excipient Compatibility for the Formulation Development of Solid Lipid Nanoparticles
14. September 2015 Solid lipid nanoparticles (SLN) are a type of a carrier system that employs solid lipids as a matrix for drug delivery.1 The drug is molecularly dispersed…
Feasibility of highly branched cyclic dextrin as an excipient matrix in dry powder inhalers –…
13. September 2015 We investigated the feasibility of highly branched cyclic dextrin (HBCD) as an excipient matrix in dry powder inhalers (DPIs). The fine particles of HBCD…
Toxicological Issues Faced after Liposomes Administration – Abstract
13. September 2015 Toxicological Issues Faced after Liposomes Administration…
A Novel submicron emulsion system loaded with doxorubicin overcome multi-drug resistance in…
13. September 2015 The purpose of the present study was to develop the Solutol HS15-based doxorubicin submicron emulsion with good stability and overcoming multi-drug…
Gattefossé opens technical centre in Mumbai
11. September 2015 Gattefossé opens technical centre in Mumbai Spread across 3500 sq feet, the centre aims at facilitating the research and formulation work and…