Low drug load, high retention mometasone furoate cream with polyglyceryl − 3 oleate as a chemical enhancer: Formulation development, in vivo and in vitro evaluation and molecular mechanisms
Abstract
The study aimed to create a low loading, high retention, easier to apply O/W mometasone furoate (MF) cream using a chemical enhancer (CE) approach to provide more options for patients with atopic dermatitis (AD) and to investigate molecular mechanisms of its increased release and retention. A Box-Behnken design determined the optimal…
Novel Drug Delivery through Use of a Foamed Excipient – Interview
18. June 2015 Formulation challenges are often associated with protein delivery vehicles, and controlled-release strategies that deliver medications locally are believed to…
Formulation Development, in Vitro Evaluation and Stability Study of Aceclofenac Tablet –…
18. June 2015 Formulation Development, in Vitro Evaluation and Stability Study of Aceclofenac Tablet…
THIOMERS – A BLESSING TO EVOLUTING ERA OF PHARMACEUTICALS – Article
17. June 2015 THIOMERS - A BLESSING TO EVOLUTING ERA OF PHARMACEUTICALS - Article THIOMERS - A BLESSING…
DNA Extraction from Plant Food Supplements: Influence of Different Pharmaceutical Excipients –…
16. June 2015 Highlights • DNA extraction is required for PFS botanical authentication studies. • The adsorption effect of talc, silica and dyes on DNA extraction was…
P-glycoprotein inhibition of drug resistant cell lines by nanoparticles – Abstract
16. June 2015 Several pharmaceutical excipients are known for their ability to interact with cell membrane lipids and reverse the phenomenon of multidrug resistance…
The Disintegration Process in Microcrystalline Cellulose Based Tablets, Part 1: Influence of…
13. June 2015 The Disintegration Process in Microcrystalline Cellulose Based Tablets, Part 1: Influence of Temperature, Porosity and Superdisintegrants - Abstract…
Chemical and Compositional Characterisation of Lactose as a Carrier in Dry Powder Inhalers –…
12. June 2015 he principal component of many solid pharmaceutical formulations and indeed of dry powder inhalers, rather than being an active pharmaceutical ingredient…
Physico-Mechanical Properties of Coprocessed Excipient MicroceLac® 100 by DM 3 Approach –…
11. June 2015 PURPOSE: To determine the effect of relative humidity (RH) and hydroxypropyl methylcellulose (HPMC) on the physico-mechanical properties of…
A review of polymers as multifunctional excipients in drug dosage form technology – Article
11. June 2015 In the article, groups of multifunctional polymers used in drug dosage form technology were classified and evaluated. These compounds, in addition to their…
CAB-O-SIL® MULTIFUNCTIONAL EXCIPIENTFOR PHARMACEUTICALS – Application Guide
11. June 2015 http://www.cabotcorp.com/solutions/applications/pharmaceuticals-and-personal-care…
Dissolution and Solubility Enhancement of the Highly Lipophilic Drug Phenytoin via Interaction with…
10. June 2015 Dissolution and Solubility Enhancement of the Highly Lipophilic Drug Phenytoin via Interaction with Poly(N-isopropylacrylamide-co-vinylpyrrolidone) Excipients -…
Optimising excipient properties for ODT formulation – Whitepaper Roquette
10. June 2015 Optimising excipient properties for ODT formulation - Whitepaper Roquette Orally disintegrating tablets (ODTs), also known as orodispersible tablets, are…
Wanted: Silica People!
10. June 2015 IPEC-Americas is looking for volunteers for a collaborative study between Silica producers, users, and the USP to confirm an IR-based identification test for…
ExcipientFest Americas 2016 – April 25-27, 2016 in Baltimore
10. June 2015
Floorplan is not available online any more.
Sponsorship Information.
Taste Masked Micropellets for Paediatric Use – Article BioPharma Asia June 2014
10. June 2015 The application of bad tasting, often bitter APIs to children requires in most cases an effective taste optimisation. This can be achieved either by the…
Innovative Pediatric HIV Treatment Formulation Gives More Children Access to Lifesaving Medications
10. June 2015
Washington, D.C.—June 8, 2015— The Elizabeth Glaser Pediatric AIDS Foundation (EGPAF) applauds the announcement of tentative approval by the U.S. Food and Drug Administration of a new antiretroviral treatment…
A PAT-based qualification of pharmaceutical excipients produced by batch or continuous processing…
09. June 2015 Highlights • Qualification of entire processes based on CQAs of the final product (excipient). • Use of analytical methods (Raman, X-ray- and laser…
Melatonin; ANN; drug delivery; hydrophilic polymers; similarity fit factors; tablet formulation…
09. June 2015 Efficacy of melatonin in treating sleep disorders has been demonstrated in numerous studies. Being with short half-life, melatonin needs to be formulated in…
Tableting technology focuses on novel coatings and continuous processes
09. June 2015 Advances in tableting technology include new formulated film coatings, novel capsule designs, and cost-saving continuous processing. Sean Ottewell reports…
Characterization of Psyllium (Plantago ovata) Polysaccharide andIts Uses – Article 2014
09. June 2015 Characterization of Psyllium (Plantago ovata) Polysaccharide and Its Uses…
TTC PROGRAM FIRST HALF 2016 with New Workshops!
08. June 2015
New Workshops
Continuous manufacturing in pharma
A forward looking approach for the production of oral solid dosage forms
Particle Engineering across the length scale
From nano to…
Formulation and In Vitro, In Vivo Evaluationof Effervescent Floating Sustained-ReleaseImatinib…
08. June 2015 Formulation and In Vitro, In Vivo Evaluationof Effervescent Floating Sustained-ReleaseImatinib Mesylate Tablet - Research Article…
Evaluating different manufacturing options to formulate loperamide HCl as orally disintegrating…
08. June 2015 Evaluating different manufacturing options to formulate loperamide HCl as orally disintegrating tablet - Poster BASF Drug Delivery Reims 2015…
Evaluating poly(vinyl acetate) as taste masking agent for paracetamol formulated in chewable tablets…
08. June 2015 Evaluating poly(vinyl acetate) as taste masking agent for paracetamol formulated in chewable tablets - Poster BASF - Drug Delivery Reims 2015…
Employing Pickering emulsions as carrier system for retinol palmitate and α-tocopherol acetate…
08. June 2015 84_447_Pickering Vit A and E_2014_Reims.…
Investigating the impact of phosphate buffer on the gel point temperature of aqueous poloxamer…
08. June 2015 85_448_Poloxamers_2014_Reims.pdf…
Announcement: STEP Database Updated – 29 Excipients now!
08. June 2015
Announcement: STEP Database Updated – 29 Excipients now!
The STEP stands for Safety and Toxicity of Excipients for Paediatrics. The Safety and Toxicity of Excipients for Paediatrics (STEP) Database is a…
Formulation of cellulose film containing permeation enhancers for prolonged delivery of propranolol…
07. June 2015 The aim of this study was to evaluate the capacity of cellulose films enriched with oleic acid and polysorbate 80 to enhance the transdermal permeation of…
Formulation and evaluation of meloxicam oral disintegrating tablet with dissolution enhanced by…
07. June 2015 Formulation and evaluation of meloxicam oral disintegrating tablet with dissolution enhanced by combination of cyclodextrin and ion exchange resins - Abstract…
Melt dispersion granules: formulation and evaluation to improve oral delivery of poorly soluble…
07. June 2015 Solid dispersion (SD) technique is a promising strategy to improve the solubility and dissolution of BCS class II drugs. However, only few products are…
Viscoelastic interactions between polydeoxyribonucleotide and ophthalmic excipients – Abstract
07. June 2015 This study investigated the interaction between polydeoxyribonucleotide (PDRN) and several ionic and nonionic isotonic agents, thickeners and a preservative…
Optimization of a novel tablets formulation using D-optimal mixture design – Full Research…
07. June 2015 Optimization of a novel tablets formulation using Doptimal mixture design…
Influence of Starting Material Particle Size on Pellet Surface Roughness – Research Article…
07. June 2015 The purpose of this study was to investigate the effect of pelletization aids, i.e., microcrystalline cellulose (MCC) and cross-linked polyvinyl pyrrolidone…
REVIEW ON THE PRODUCTION OF PELLETS VIA EXTRUSION- SPHERONISATION EXCLUSIVE OF MICROCRYSTALLINE…
07. June 2015 REVIEW ON THE PRODUCTION OF PELLETS VIA EXTRUSION- SPHERONISATION EXCLUSIVE OF MICROCRYSTALLINE…