Low drug load, high retention mometasone furoate cream with polyglyceryl − 3 oleate as a chemical enhancer: Formulation development, in vivo and in vitro evaluation and molecular mechanisms
Abstract
The study aimed to create a low loading, high retention, easier to apply O/W mometasone furoate (MF) cream using a chemical enhancer (CE) approach to provide more options for patients with atopic dermatitis (AD) and to investigate molecular mechanisms of its increased release and retention. A Box-Behnken design determined the optimal…
Formulation of taste masked, compression coated, immediate release tablets of oseltamivir phosphate…
27. May 2015 Bala Bharathi P and Madhavi B L R*Dept. of Pharmaceutics, RBVRR…
Formulation and evaluation of pantaprazole transdermal patches for enhanced therapeutic efficacy
27. May 2015 M.R.Shivalingam*1,A.Vineela2, K.Vaishnavi1, Ch.Sunanda1, V.Abraham…
Application of Hot Melt Extrusion Technology in Drug Product Development
26. May 2015
Application of Hot Melt Extrusion Technology in Drug Product Development - 8th Annual Charles I. Jarowski Symposium - June 17-18, 2015St. University, Queens, NY
Hot melt extrusion has been used in the…
Semi-solid materials for controlled release drug formulation:current status and future prospects…
26. May 2015 Semi-solid materials for controlled release drug formulation: current status and future…
Cyclosporine A Loaded Self-nanoemulsifying Drug Delivery System (SNEDDS): Implication of Functional…
26. May 2015 The present work focusses on the formulation development and evaluation of functional excipient (surfactant stabilizer), Vitamin E TPGS loaded…
Grace: silica gel plant certification will cut customer audit burden
26. May 2015 By Gareth MacDonald+Gareth MACDONALD, 26-May-2015WR Grace says certification for its excipient plant in Germany will reduce the audit burden faced by drug…
Evonik plans to build a new production plant for precipitated silica in the United States
26. May 2015 May 26, 2015 Largest investment in North America in the past five years Completion of the plant is scheduled for the end of 2017 Energy-saving tire trend…
Formulation of bi-layer matrix tablets of tramadol hydrochloride: Comparison of rate retarding…
26. May 2015 Formulation of bi-layer matrix tablets of tramadol hydrochloride: Comparison of rate retarding ability of the incorporated hydrophilic polymers - Abstract…
Role of excipients in the crystallization of Albendazole – Abstract
26. May 2015 Highlights • Solubility and dissolution of Albendazole was greatly enhanced. • Benzoic acid generated hydrogen bonding with drug and changed crystal habit.…
ODT – OVERCOMING YOUR MAIN CHALLENGES – a Roquette Pharma Webinar May 28, 2015
25. May 2015 Orally Disintegrating Tablets (ODTs) are getting increasingly interesting delivery systems in the Pharmaceutical and Nutraceutical fields. …
The New Era Of Functional Excipients – An Innovative Approach In Design Of Dosage Forms…
25. May 2015 The New Era Of Functional Excipients - An Innovative Approach In Design Of Dosage Forms - a Pharmaceutical Processing Article from 2011…
Optimizing Biologics Formulation Development – January 18-22, 2016 in San Diego
24. May 2015 Formulation Strategies for Different Stages of Development, New Product Formats, Device/Delivery Systems and Emerging Analytical Methods January…
Understanding the impact of microcrystalline cellulose physicochemical properties on tabletability…
The quality by design (QbD) initiative is promoting a better understanding of excipient performance and the identification of critical material attributes (CMAs). Despite microcrystalline cellulose (MCC) being one of the most popular…
Nisso opens expanded HPC plant on back of pharma demand
23. May 2015 By Dan Stanton+, 11-May-2015 Recent US FDA approval of products containing the excipient HPC has driven demand, according to Nippon Soda (Nisso) which…
CPhI Worldwide Announces 2015 Expert Panel
23. May 2015 Kurt Nielson (Catalent), Vivek Sharma (Piramal) and Alan Sheppard (IMS Health) join panel CPhI Worldwide, organised by UBM EMEA, announces its expert…
Challenges and Opportunities in Oral Formulation Development
Introduction
Over 60% of new chemical entities that are poorly soluble qualify either as BCS Class II or Class IV and they provide challenges as well as opportunities to scientists working in formulation development . The…
From food to pharma: The polyhedral nature of polymers” – 9° Annual Meeting – Milano…
23. May 2015 Event Program 25 May 2015 - Natural polymers in the Food and Industrial World 26 May 2015 - Natural polymers in the Pharmaceutical World…
Formulation and evaluation of nanocrystalline cellulose as a potential disintegrant
23. May 2015 Disintegrant is a typical excipient that improves the solubility, dissolution and bioavailability of drug. In this study, the application of nanocrystalline…
Head-To-Head Comparison of Different Solubility-Enabling Formulations of Etoposide and Their…
23. May 2015 The purpose of this study was to conduct a head-to-head comparison of different solubility-enabling formulations, and their consequent solubility–permeability…
Synthesis, characterization of thiolated karaya gum and evaluation of effect of pH on its…
23. May 2015 Highlights • Thiolated gum karaya was found to contain 5.026 mM of thiol groups/gm of polymer. • Thiolation led to conjugates with improved properties…
Effect of lubricants when making tablets containing MCC and SMCC
23. May 2015 From the May 2015 issue of Tablets & Capsules. http://bit.ly/TabLube01515
Grace European Facility Receives GMP Excipient Certification for SYLOID® FP Silica Gel
WORMS, GERMANY – May 26, 2015 – W. R. Grace & Co. (NYSE: GRA) announces that its manufacturing facility in Worms, Germany has received good manufacturing practice (GMP) certification from EXCiPACT™, an independent organization that…
Emilio Castelli achieves IPEC PQG GMP 2006 standard for Sugar Spheres
22. May 2015 Emilio Castelli established the Sugar Spheres production in 1968 to serve the pharmaceutical industry. http://ecastelli.com…
Formulation Development of Spherical Crystal Agglomerates of Itraconazole for Preparation of…
22. May 2015 The objective of the present work was to formulate tablet dosage form of itraconazole with enhanced bioavailability. Spherical crystal agglomerates (SCA) of…
Trends in Demand for Various Excipients
22. May 2015 Pharmaceutical excipients, a broad array of substances blended with active ingredients into desired finished dosage forms, have, in recent years, made…
Metoprolol Tartrate Sustained-release Binary Matrix Microspheres for Oral Administration Produced by…
20. May 2015 A novel self-developed technique ultra-fine particle process system (UPPS) which is quite different from existing technology was employed to prepare…
Understanding the impact of microcrystalline cellulose physicochemical properties on tabletability
20. May 2015 The quality by design (QbD) initiative is promoting a better understanding of excipient performance and the identification of critical material attributes…
FORMULATION AND EVALUATION OF BILAYER TABLETS OF BACLOFEN USING SYNTHETIC POLYMERS
20. May 2015 FORMULATION AND EVALUATION OF BILAYER TABLETS OF BACLOFEN USING *P.K.…
Self nano-emulsifying drug delivery system for Embelin: Design, characterization and in-vitro…
20. May 2015 The objective of the present study was to prepare solid self-nanoemulsifying drug delivery system (S-SNEDDS) containing Capryol-90 as oil phase for the delivery…
Characterization of a New High-Dose Dry Powder Inhaler (DPI) Based on a Fluidized Bed Design
20. May 2015 The objective of this study was to develop a new high-efficiency dry powder inhaler (DPI) that can effectively aerosolize large masses (25–100 mg) of spray…
ExcipientFest Americas 2015 Attendance Breakdown
20. May 2015
Another successful ExcipientFest with over 450 participants was held April 28-29, 2015 in San Juan Puero Rico. See the statistics...
https://newsismybusiness.com/excipientfest-americas-slated/…
Moisture Activated Dry Granulation (MADG) with Syloid® XDP Silica
20. May 2015 M484_Grace_SyloidXDP_Moisure_activated_d…
Use of insulin in diabetes: a century of treatment
19. November 2015 Savita Shahani, MD1; Lokesh Shahani, MD21 Department of…