Low drug load, high retention mometasone furoate cream with polyglyceryl − 3 oleate as a chemical enhancer: Formulation development, in vivo and in vitro evaluation and molecular mechanisms
Abstract
The study aimed to create a low loading, high retention, easier to apply O/W mometasone furoate (MF) cream using a chemical enhancer (CE) approach to provide more options for patients with atopic dermatitis (AD) and to investigate molecular mechanisms of its increased release and retention. A Box-Behnken design determined the optimal…
Pulmonary Drug Delivery—Particle Engineering for Inhaled Therapeutics
21. April 2015 Industry experts discuss the various factors affecting drug delivery to the lungs and key considerations when developing inhalation formulations.…
Particle engineering for inhalationformulation and delivery of biotherapeutics
21. April 2015 Peter Mack, Katie Horvath, Andres Garcia, Janet Tully and Benjamin Maynor Liquidia Technologies - August 2012 Advances in particle engineering and…
Tableting Performance of Silicified Cassava Starch as a Directly Compressible Excipient
20. April 2015 ABSTRACT The aim of this study was to evaluate the direct compression behaviour of co-processed cassava starch and colloidal silica in the formulation of…
Orodispersible films and tablets with prednisolone microparticles
20. April 2015 Witold Brniak, Ewelina Maślak, Renata Jachowicz doi:10.1016/j.ejps.2015.04.006…
Formulation strategies and particle engineering technologies for pulmonary delivery of…
18. April 2015 Curr Pharm Des. 2015 Apr 15. Cun D, Wan F, Yang M1. Biopharmaceuticals including recombinant proteins, monoclonal antibody and nucleic acid based…
Europe’s baby meds contain potentially harmful additives
(Reuters Health) - Two-thirds of newborns in Europe who received common medicines were exposed to a potentially dangerous substance in the medication, according a new study.
The study did not look at whether the babies were…
Big firms dominate solubility sector but demand creating space for small players, says Kline &…
17. April 2015 Big firms dominate solubility sector but demand creating space for small players, says Kline & Co By Gareth MacDonald+, 16-Apr-2015 BASF, Abitec…
Separation of Active Pharmaceutical Ingredients (APIs) from Excipients in Pharmaceutical…
17. April 2015 Jerry L. Atwood Cryst. Growth Des., Just Accepted Manuscript DOI: 10.1021/acs.cgd.5b00317 Publication Date (Web): April 16, 2015 Copyright © 2015…
Product Finder-Overview from Colorcon – Pharma Excipients
17. April 2015
Colorcon® provides a wide range of pharmaceutical film coatings and pharmaceutical formulation development assistance ...
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Lactose Excipients by Armor Pharma
15. April 2015
Our quest for excellence has led us to a sustainable level of product development : a structured range of lactose for the formulation of Oral Solid Dosage Forms and Dry Powder Inhalers, which…
GMPs for Excipient Makers Move Ahead
15. April 2015 The FDA is edging toward requiring pharmaceutical excipient makers to adopt quality systems and has collaborated with standards development groups in…
Formulation and development of pH-independent/dependent sustained release matrix tablets of…
13. April 2015 The objective of the present study was to develop pH-independent/dependent sustained release (SR) tablets of ondansetron HCl dihydrate (OND), a selective…
Guidance for IndustryLimiting the Use of Certain Phthalates as Excipients in CDER-Regulated Products
11. April 2015 Guidance for Industry Limiting the Use of Certain Phthalates as Excipients in CDER-Regulated…
Stabilisation of amorphous ibuprofen in Upsalite, a mesoporousmagnesium carbonate, as an approach to…
11. April 2015 Stabilisation of amorphous ibuprofen in Upsalite, a mesoporous magnesium carbonate, as an…
A Template-Free, Ultra-Adsorbing, High Surface Area Carbonate Nanostructure
11. April 2015 Johan Forsgren , Sara Frykstrand ,Kathryn Grandfield,Albert Mihranyan ,Maria Strømme Published: July 17, 2013DOI:…
CONTINUOUS PROCESSING AT INTERPHEX 2015
08. April 2015 MODCOS by Glatt Continuous Process Train comprising metering…
Direct compression of medicated chewing gum
08. April 2015
Article published in Tablets & Capsules in January 2013
In this edition of the column, Javier Belmar and Marc Ribé of Cafosa discuss the formulation and manufacture of direct-compression medicated…
IPEC calls for excipient GMP standard implementation plans to be in place by Q4
08. April 2015 By Zachary Brennan IPEC-Americas (International Pharmaceutical Excipient Council) stopped short of recommending a specific date for implementation of a new…
Formulation and evaluation of floating mucoadhesive alginate beads for targeting Helicobacter …
07. April 2015 OBJECTIVES: There are various obstacles in the eradication of Helicobacter pylori infections, including low antibiotic levels and poor accessibility of the…
An Apparatus to Deliver Mannitol Powder for Bronchial Provocation in Children Under Six Years Old.
07. April 2015 Currently bronchial provocation testing (BPT) using mannitol powder cannot be performed in children under 6 years. A primary reason is it is challenging for…
Formulation considerations in the design of topical, polymeric film-forming systems for sustained…
07. April 2015 Polymeric film-forming systems (FFSs) are potential drug delivery systems for topical application to the skin. The FFSs form thin and transparent polymeric…
Formulation studies on ibuprofen sodium–cationic dextran conjugate: effect on tableting and…
07. April 2015 The effect of electrostatic interaction between ibuprofen sodium (IbS) and cationic diethylaminoethyl dextran (Ddex), on the tableting properties and…
Development of subcutaneous sustained release nanoparticles encapsulating low molecular weight…
06. April 2015 The objective of the present research work was to prepare and evaluate sustained release subcutaneous (s.c.) nanoparticles of low molecular weight heparin…
Formulation and characterization of sustained release dosage form of moisture sensitive drug.
06. April 2015 OBJECTIVE: The purpose of this study was to prepare sustained release tablet of moisture sensitive drug like Ranitidine Hydrochloride for treatment of…
Formulation of rizatriptan benzoate fast dissolving buccal films by emulsion evaporation technique
06. April 2015 Int J Pharm Investig. 2015 Apr-Jun; 5(2): 101–106. doi: 10.4103/2230-973X.153387 Suryadevara…
Management of the Supply Chain: Excipients & API – Pharmaceutical Quality System (IC Q…
05. April 2015 Management of the Supply Chain: Excipients & API - Pharmaceutical Quality System (IC Q 10) Conference - November 2011…
Production of Highly Charged Pharmaceutical Aerosols Using a New Aerosol Induction Charger
05. April 2015 Purpose Properly charged particles can be used for effective lung targeting of pharmaceutical aerosols. The objective of this study was to characterize the…
Kinetically stable propofol emulsions with reduced free drug concentration for intravenous delivery
05. April 2015 Purpose Intravenous injections of propofol emulsions are accompanied by pain likely due to the interaction of the dissolved drug with endothelial cells of…
IPEC Americas: Announcing the Revised IPEC Glossary of Terms!
04. April 2015 IPEC Americas: Announcing the Revised IPEC Glossary of Terms! http://multibriefs.com/briefs/ipec/IPEC_Glossary.pdf
Strengthening our Culture of Quality – Ajaz S. Hussein – QbD and CoQ IDMA Mumbai 24…
01. April 2015 Strengthening our Culture of Quality - Ajaz S. Hussein - QbD and CoQ IDMA Mumbai 24 March 2015 Ajaz S. Hussain, Ph.D. , Executive…
Excipient Knowledge Management: 2015 and beyond – Ajaz S. Hussein – Mumbai 12 March 2015
01. April 2015 Ajaz S. Hussain, Ph.D., Executive Director at The National Institute for Pharmaceutical Technology and Education…
IPEC Position Paper – Implementation of NSF/IPEC/ANSI 363-2014
01. April 2015
IPEC-Americas Position Paper
Implementation of the NSF/IPEC/ANSI 363 – 2014 Excipient GMP Standard
The American National Standards Institute (ANSI) excipient Good Manufacturing Practices standard…
Excipient properties affecting the mechanical performance of abuse deterrent formulations
01. April 2015 GUDFA Abuse deterrent mtg Oct14.pdf…