Low drug load, high retention mometasone furoate cream with polyglyceryl − 3 oleate as a chemical enhancer: Formulation development, in vivo and in vitro evaluation and molecular mechanisms
Abstract
The study aimed to create a low loading, high retention, easier to apply O/W mometasone furoate (MF) cream using a chemical enhancer (CE) approach to provide more options for patients with atopic dermatitis (AD) and to investigate molecular mechanisms of its increased release and retention. A Box-Behnken design determined the optimal…
Silica nanoparticles: Preparation, characterization and in vitro/in vivo biodistribution studies
21. February 2015 The aim of the present study was to characterize and evaluate both in vitro, by microscopy techniques, and in vivo, by scintigraphic imaging, the…
Optimization of combinational intranasal drug delivery system for the management of migraine by…
21. February 2015 Animesh Kumar, Tarun Garg, Ganti S. Sarma, Goutam Rath, Amit Kumar Goyal, Department of Pharmaceutics, I.S.F. College of…
An Overview of Natural Polysaccharides as Biological Macromolecules:Their Chemical Modifications and…
21. February 2015 An Overview of Natural Polysaccharides as Biological Macromolecules: Their Chemical…
Emisphere Highlights Positive Phase 2 OG217SC Data From Eligen(R) Licensee Novo Nordisk
20. February 2015
ROSELAND, N.J., Feb. 20, 2015 (GLOBE NEWSWIRE) -- Emisphere Technologies, Inc. (OTCBB:EMIS) today highlighted positive Phase 2 data from Eligen® licensee Novo Nordisk pertaining to OG217SC, the oral…
Detection of Pharmaceutical Drug Crystallites in Solid Dispersions by Transmission Electron…
20. February 2015 Ralm G. Ricarte †, Timothy P. Lodge *†‡, and Marc A. Hillmyer *‡ †Department of Chemical Engineering and Materials Science and ‡Department of Chemistry,…
IPEC-Americas Submits Comments on FDA’s ANDA Submissions – Refuse-to-Receive Standards…
18. February 2015 IPEC-Americas Submits Comments on FDA's ANDA Submissions - Refuse-to-Receive Standards Guidance for Industry …
Influence of non-water-soluble placebo pellets of different sizes on the characteristics of orally…
18. February 2015 ABSTRACT The present study describes the development of an orally disintegrating tablet containing a non-water-soluble drug delivery system. A model…
Preparation and characterization of controlled-release doxazosin mesylate pellets using a simple…
Pellets are one of multiparticulate pharmaceutical forms and can offer numerous technical and biopharmaceutical advantages compared with single dose unit formulations, e.g. tablets and capsules. This study aimed at formulation of…
Fluidised Bed Microencapsulation of Ascorbic Acid: Effectiveness of Protection under Simulated…
18. February 2015
This study investigates the use of microencapsulation by fluidised bed coating for the protection of ascorbic acid during long-term storage under simulated tropical conditions. Microencapsulation…
Preparation of Microcrystalline Cellulose from Cotton and its Evaluation as Direct Compressible…
17. February 2015 Md Nurul Islam Setu, Md Yeunus Mia, Nur Jaharat Lubna, Abu Asad Chowdhury DOI: http://dx.doi.org/10.3329/dujps.v13i2.21899 Dhaka Univ. J. Pharm.…
Synthesis and evaluation of the structural and physicochemical properties of carboxymethyl…
17. February 2015 Sonia Lefnaoui, , Nadji Moulai-Mostefa Open Access funded by King Saud University - Saudi Pharmaceutical Journal…
Integration of active pharmaceutical ingredient solid form selection and particle engineering into…
17. February 2015 Ticehurst, M. D. and Marziano, I. (2015), Integration of active pharmaceutical ingredient solid form selection and particle engineering into drug…
Evaluation of physicochemical character of Ipomoea batata starch as a pharmaceutical excipient
17. February 2015 Kusuma R et al., (2014) Int. J. Res. Pharm. Sci., 5(4),…
Xanthan gum: A versatile biopolymer for biomedical and technological applications
16. February 2015 Denise F. S. Petri* Article first published online: 16 FEB 2015 DOI: 10.1002/app.42035…
The Implications of Implementing the Directive on Falsified Medicines
The trade in illegal pharmaceuticals is a global problem for public health. The transgressions of the rules that govern the distribution and marketing of medicinal products comes in many different forms, including substandard…
A Practical Approach of Implementing GMP for Excipients
15. February 2015 Sep 01, 2014 By Frithjof Holtz , Patricia Rafidison , Stephan Rönninger Pharmaceutical Technology…
EFCG Press Conference CPhI 2014: Excipients
15. February 2015
Pharmaceutical Excipients: Global Business Developments
by Tony Scott
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Dextran and its potential use as tablet excipient
15. February 2015 Dextrans are a class of carbohydrate polymers extensively applied in pharmaceutical applications, particularly as drug conjugate macromolecular carriers or…
Insights into the biopharmaceutical behavior of oral lipid-based formulations using advanced…
13. February 2015 Stillhart, Cordula Edith. Insights into the biopharmaceutical behavior of oral lipid-based formulations using advanced analytical techniques and…
REVIEW ON NATURAL POLYSACCHARIDE BASED PARTICULATE DRUG DELIVERY SYSTEMS: AN INIMITABLE TACTIC IN…
12. February 2015
ROHIT RAJENDRA BHOSALE*, RIYAZ ALI M. OSMANI, AFRASIM MOIN.
Department of Pharmaceutics, JSS College of Pharmacy, Mysore, Karnataka, India.
IJCPR,Vol6,Issue1,Article2.pdf
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CAPSULES PRODUCTION. MICROCAPSULES.
HARD AND SOFT GELATIN CAPSULES
Capsules are solid oral dosage forms in which the drug is enclosed within a hard or soft shell. The shell is normally made from gelatin and results in a simple, easy - to - swallow formulation with no…
EXCiPACT has launched a Linkedin Group
11. February 2015 EXCiPACT™ is a voluntary international scheme to provide independent 3rd party certification of manufacturers, suppliers and distributors of…
Compaction Simulation Forum – June 16-17, 2015 in Copenhagen
10. February 2015 The Compaction Simulation Forum (CSF) was formed in order to better leverage industry, academic experience and learning with compaction simulation...…
Diclofenac sodium pellets for flexible pediatric drug dosing:Preparation, characterization and…
09. February 2015 Diclofenac sodium pellets for flexible pediatric drug dosing:Preparation, characterization and evaluation Scholars Research Library - Der Pharmacia Lettre,…
List of US FDA DMF Type IV as per 4th quarter 2014
09. February 2015 List of US FDA DMF Type IV as per 4th quarter 2014 List of active DMF Type IV as per…
Formulation of Eco-friendly Medicated Chewing Gum to Prevent Motion Sickness.
09. February 2015 AAPS PharmSciTech. 2015 Feb 6. Shete RB1, Muniswamy VJ, Pandit AP, Khandelwal KR. http://www.ncbi.nlm.nih.gov/pubmed/25652732?dopt=Abstract…
Diffusion and Swelling Measurements in Pharmaceutical Powder Compacts Using Terahertz Pulsed Imaging
08. February 2015 Samy Yassin, Ke Su, Hungyen Lin, Lynn F. Gladden and J. Axel Zeitler* Article first published online: 2 FEB 2015…
Biowaiver Monographs for Immediate Release Solid Oral Dosage Forms: Levetiracetam
08. February 2015 Article first published online: 6 FEB 2015 DOI: 10.1002/jps.24350 http://onlinelibrary.wiley.com/doi/10.1002/jps.24350/full …
A Self-microemulsifying Drug Delivery System (SMEDDS) for a Novel Medicative Compound Against…
08. February 2015
AJS is the code name of an untitled novel medicative compound synthesized by the Tasly Holding Group Company (Tianjin, China) based on the structure of cinnamamide, which is one of the Biopharmaceutics…
Spontaneous Vesicle based Excipient Formation in Mixtures of Sodium N-(n-Alkanoyl)-L-alaninate and…
07. February 2015 http://pubs.acs.org/doi/abs/10.1021/ie503697c
A bitter pill to swallow – the excipient approval process
05. February 2015 The current practices for new excipient approval by regulatory agencies are grossly inefficient and hinder innovation. As many drugs’ patents expire, the…
Design of bilayer tablets using modified Dioscorea starches as novel excipients for immediate and…
05. February 2015 AdenikeOkunlola*Department of Pharmaceutics and Industrial…