Low drug load, high retention mometasone furoate cream with polyglyceryl − 3 oleate as a chemical enhancer: Formulation development, in vivo and in vitro evaluation and molecular mechanisms
Abstract
The study aimed to create a low loading, high retention, easier to apply O/W mometasone furoate (MF) cream using a chemical enhancer (CE) approach to provide more options for patients with atopic dermatitis (AD) and to investigate molecular mechanisms of its increased release and retention. A Box-Behnken design determined the optimal…
Lipids in Transdermal and Topical Drug Delivery
04. February 2015 John B. Cannon, Ph.D. - Posted: December 01, 2014…
Diffusion and Swelling Measurements in Pharmaceutical Powder Compacts Using Terahertz Pulsed Imaging
03. February 2015 SAMY YASSIN, KE SU, HUNGYEN LIN, LYNN F. GLADDEN, J. AXEL…
Comparing Drug Layering and Direct Pelletization Processes
03. February 2015 The extended-release performance of drug-loaded pellets manufactured by two methods, drug layering and direct pelletization, was compared. Mar 02, 2014…
Production and Characterization of Rapidly Dissolving Cryopellets
01. February 2015
Matthias Erber* and Geoffrey Lee
Article first published online: 28 JAN 2015
DOI: 10.1002/jps.24371
Quality is Key – CPhI experts make predictions on pharma trends for 2015
01. February 2015 Quality is Key - CPhI experts make predictions on pharma trends for 2015 Jan 30, 2015 - By PharmTech Editors Link to…
Abuse-Deterrent Opioid Formulations: Purpose, Practicality, and Paradigms
28. January 2015
Abuse-Deterrent Opioid Formulations: Purpose, Practicality, and Paradigms
Jeffrey Fudin, BS, PharmD, DAAPM, FCCP
When reflecting on commonly abused drugs, pharmacists generally focus…
BASF to take on Asian PVP producers and target generics firms with new capacity in China
25. January 2015 By Gareth MacDonald+Gareth MACDONALD, 23-Jan-2015BASF will spend €56m ($62m) to increase production capacity for the excipient PVP by expanding existing…
EMA Sets Elemental Impurities Implementation Dates
25. January 2015 Jan 23, 2015 - By PharmTech Editors http://www.pharmtech.com/ema-sets-elemental-impurities-implementation-dates
EXCiPACT – Events
22. January 2015
EXCiPACT - Events
28-29 Apr 2015 – Making Pharmaceuticals Conference – Birmingham, UK
NMM Exhibition Centre, Birmingham, UK 28/04/2015 - 29/04/2015
24 Mar 2015 Excipient Quality…
Innovative Excipients in Solid-Dosage Manufacturing
22. January 2015 This article looks at key considerations in excipient selection during formulation development and their impact on the performance of the finished drug…
Eliminating Tablet Spots and Specks
22. January 2015 Although the source of spots and specks on tablets is sometimes difficult to identify, following good maintenance and manufacturing practices can help solve…
IPEC – PQRI Survey on Impact of Excipient Variability on Drug Product Manufacturing
22. January 2015
http://ipecamericas.org
Excipient pharmacokinetics and profiling
18. January 2015 Int J Pharm. 2015 Jan 14. pii: S0378-5173(15)00035-6. doi: 10.1016/j.ijpharm.2015.01.022. http://www.ncbi.nlm.nih.gov/pubmed/25596414
PAT & Quality by Design 23-25 March, London
18. January 2015
PAT & Quality by Design 23-25 March, London
Excipient foods’ show promise in enhancing nutrient bioavailability
15. January 2015 By Nathan Gray+Nathan GRAY, 14-Jan-2015Improving the design of functional and finished products by better understanding the role of excipient foods could…
Investigation of Drug-Excipient Interactions in Lapatinib Amorphous Solid Dispersions Using…
15. January 2015 Yang Song , Xinghao Yang , Xin Chen , Haichen Nie , Stephen Byrn , and Joseph W. Lubach Mol. Pharmaceutics, Just Accepted ManuscriptDOI:…
Co-processed microcrystalline cellulose and sugar alcohol as an excipient for tablet formulations
15. January 2015 United States Patent 8932629 Assigne: FMC Corporation (Philadelphia, PA, US) http://www.freepatentsonline.com/8932629.html
The Effect of Microcrystalline Cellulose Crystallinity on the Hydrophilic Property of Tablets and…
15. January 2015 as Active Pharmaceutical Ingredient Inside Tablets AAPS PharmSciTech January 2015 http://link.springer.com/article/10.1208/s12249-014-0276-7…
Capsugel buys ionic liquid tech IP to enhance lipid-based drug solubility
12. January 2015 By Dan Stanton+, 12-Jan-2015 Capsugel has acquired a technology platform which uses ionic liquids to enhance the solubility of lipid-based drug…
Application of StarCap 1500® as Filler/Binder/Disintegrant in a Roller Compaction Dry Granulation…
11. January 2015 Zahra N. Mahmoudi, Ngoc Do, Thomas P. Farrell and Ali R.…
IPEC – December Committee Meetings Recap
08. January 2015 http://multibriefs.com/briefs/ipec/IPEC_Dec_Committee_Week_Summary.pdf
Excipient Variability and Its Impact on Dosage Form Functionality
06. January 2015 Vivek S. Dave1,*, Suprit D. Saoji2,Nishikant A. Raut2 andRahul V. Haware3 Article first published online: 5 JAN 2015…
Considerations in Developing Sublingual Tablets—An Overview
03. January 2015 This review highlights relevant physicochemical drug properties and formulation design considerations critical to quality and performance of the sublingual…
Draft Guidance Document – Tamper-Resistant Formulations of Opioid Drug Product Submissions
29. December 2014 Consultation on the Draft Guidance Document: Tamper-resistant Formulations of Opioid Drug Product Submissions Opioid drugs are subject to the Food…
Spectrum Pharmaceuticals Files a New Drug Application with the FDA for Captisol-Enabled™ (Propylene…
29. December 2014 http://www.businesswire.com/news/home/20141226005014/en/Spectrum-Pharmaceuticals-Files-Drug-Application-FDA-Captisol-Enabled™#.VKGD-50HAIM…
Tender Portal of Government of India
28. December 2014 http://eprocure.gov.in/epublish/app?component=%24DirectLink&page=Home&service=direct&sp=257644 I have found this tender including…
List of US FDA DMF Type IV as per 3rd quarter 2014
18. December 2014 List of active DMF Type IV as per 3rd quarter 2014 The list is…
IPEC-Americas aims to make drug excipient users TUPP aware
16. December 2014 By Gareth MacDonald+, 15-Dec-2014 Manufacturers should profile the "black specks" created during excipient production and share details…
Design and development of co-processed excipients for fast dissolving tablets of Irbesartan by melt…
14. December 2014 http://link.springer.com/article/10.1007/s40005-014-0163-y