Unraveling the Impact of the Oil Phase on the Physicochemical Stability and Skin Permeability of Melatonin Gel Formulations
Abstract
Melatonin’s antioxidant properties make it a valuable component in anti-aging semisolid topical products. This study explores the role of Pemulen®, an acrylic-based viscosifying agent, in stabilizing cream-gel formulations. Remarkably, even at low concentrations (0.4%), Pemulen® successfully produced physicochemical stable topical…
Speciality Cellulose – Report Credit Suisse from 2011 on Sateri
09. March 2014 The general financial information on the company are not of importance. But there is an interesting overview on the use of speciality cellulose and…
Preparation and characterization of spray-dried powders intended for pulmonary delivery of Insulin…
03. March 2014 Seyed Salman Razavi Rohania,Khalil Abnousb,Mohsen Tafaghodia http://www.sciencedirect.com/science/article/pii/S0378517314001239
Pediatric Formulations – A Roadmap
03. March 2014 Series: AAPS Advances in the Pharmaceutical Sciences Series, Vol. 11 Bar-Shalom, Daniel, Rose, Klaus (Eds.) 2014, XV, 439 p. 76 illus., 36 illus. in…
The Rietveld Method as a Tool to Quantify the Amorphous Amount of Microcrystalline Cellulose
02. March 2014 Laysa Pires De Figueiredo, Fabio Furlan Ferreira* Article first published online: 1 MAR 2014 DOI: 10.1002/jps.23909…
AAPS Webinar: Impact on Excipients on Oral Drug Availability
27. February 2014 eLearning event will discuss how measures of excipient variability should be studied during drug development …
Formulation Development and Evaluation of Fast Disintegrating Tablet of Cetirizine Hydrochloride: A…
24. February 2014 Deepak Sharma,1 Mankaran Singh,2 Dinesh Kumar,3 and Gurmeet Singh4 1Department of Pharmaceutics, Rayat Bahra Institute of Pharmacy, Hoshiarpur-146001,…
Connell Brothers Expands Partnership with FMC to Japan
19. February 2014 http://en.acnnewswire.com/press-release/english/15674/connell-brothers-expands-partnership-with-fmc-to-japan
Natural Excipients – Uses of Pharmaceutical Formulations
18. February 2014 http://www.sphinxsai.com/2014/PharmTech/PDF/PT=04(21-28)JM14.pdf
Preparation and characterization of PEGylated chitosan nanocapsules as a carrier for pharmaceutical…
17. February 2014 Alireza Hassani Najafabadi, Majid Abdouss, Shahab Faghihi http://link.springer.com/article/10.1007/s11051-014-2312-7
Application of QbD Principles for the Evaluation of Empty Hard Capsules as an Input Parameter in…
14. February 2014
Understanding the product and process variable on the final product performance is an essential part of the quality-by-design (QbD) principles in pharmaceutical development. The hard capsule is an…
Commonly Used Excipients Modulate UDP-Glucuronosyltransferase 2B7 Activity to Improve Nalbuphine…
14. February 2014 Hong-Jaan Wang, Cheng-Huei Hsiong, Shung-Tai Ho, Min-Jen Lin, Tung-Yuan Shih, Pei-Wei Huang, Oliver Yoa-Pu Hu…
EXCiPACT Becomes Free-Standing Association Under Belgium Law
11. February 2014 The Board of Directors of the new EXCiPACT asbl, formerly a project of the IPEC Federation, has become a free-standing, not-for-profit association under…
Why use excipient human serum albumin (HSA)?
09. February 2014 Human Serum Albumin (HSA) is a natural protein found in the human body. It has proven preferable to artificial mediums, ideal as a stabilizer in…
IPEC Foundation Now Accepting Award Applications
05. February 2014
The IPEC-Americas Foundation is now accepting applications for the Ralph Shangraw Memorial Award, the Industrial Research Award and five graduate student travelships to attend the AAPS 2014…
Shear-Thinning Rheology of the Abuse-Deterrent Dosage Form Extracts
Prescription drug abuse has become a worldwide public health issue. Of particular concern is the dose-dumping effect caused by co-ingestion of ethanol which leads to premature rapid release of the drug load. Also, medications can…
Eyes On Excipients
Inactive but essential drug ingredients are getting checked out with modern rigor to ensure their quality
By Jyllian Kemsley
Chemical and Engineering News
Volume 92 Issue 5 | pp. 9-11
Issue Date: February 3, 2014…
Global OSDF Excipients Demand to Grow at 4.5% CAGR to 20
Demand will be driven by the growth of the global pharmaceutical market amid increasing aging population, coupled with the development and introduction of new excipients that exhibit improved properties such as flowability.…
Film Coating For Pediatric Oral Solid Dosage Forms
01. February 2014
by Colorcon
http://www.pharmaceuticalonline.com/doc/film-coating-for-pediatric-oral-solid-dosage-forms-0001?goback=%2Egmr_3294652%2Egde_3294652_member_5835356213893693444
FAQs on Pharmaceutical Excipients by IPEC Americas Foundation
30. January 2014
by IPEC Americas Foundation
http://www.ipecfoundation.org/faqs
The Role of Different Binary Binder Systems on Ibuprofen-Tablets by Dry Granulation (Roller…
P. Müsse, Hochschule Fresenius University of Applied Sciences, 65510 Idstein, Germany / Dr. M. Yunis, BIOGRUND GmbH, 65510 Huenstetten, Germany
Introduction: Dry granulation (roller compaction) as a continuous process…
Rapid and Lossless Screening of Hot-Melt Extruded Formulations
D. Treffer, MeltPrep GmbH, Nikolaiplatz 4/3, 8020 Graz Austria
Introduction:
Hot-melt extrusion is a process originally developed for the plastics industry. It is well established in the plastics industry and is applied…
Tricalcium Citrate – A New Brittle Tableting Excipient for Direct Compression and Dry…
V. Hagelstein1, M. Gerhart2, K.G. Wagner3
1 Department of Pharmaceutical Technology and Biopharmaceutics, University of Bonn, 53121 Bonn, Germany
2 Jungbunzlauer Ladenburg GmbH, 68526 Ladenburg, Germany
3 Department of…
Crystallization kinetics in amorphous solid dispersions can be quantified by water sorption…
INTRODUCTION
Most new active pharmaceutical ingredients (APIs) exhibit a very low solubility in water, leading to an insufficient absorption in the gastrointestinal tract and thus poor bioavailability. Several…
Moisture-induced amorphous amorphous phase separation can be predicted
Gabriele Sadowski; Christian Luebbert
Department of Biochemical and Chemical Engineering, Laboratory of Thermodynamics, TU Dortmund University, Emil-Figge-Str. 70, D-44227 Dortmund, [email protected], +49 231 755…
Efficient taste masking through high shear coatingwith lipid excipients
Y Rosiaux1, A Forest1, JM Girard1, C Deleglise1, D Marchaud1
1Gattefossé SAS, 36 chemin de Genas, 69804 Saint-Priest, France, [email protected]
Introduction:
Solid lipid excipients can be used as taste masking agents…
AAPS 2017 Posters
Evaluation of Coating Performance of INSTACOAT™ 4G In The BectochemPerforated Pan
Evaluation Of Coating Performance Of INSTACOAT™ 4G In The Bectochem Perforated Pan
AAPS - Bectochem Perforated Pan.pdf
Adobe…
AAPS 2017 Posters
Determination of Processing Window for Hot Melt Extrusion and Milling of Hypromellose Acetate Succinate by Assessing Thermal Degradation
Determination of Processing Window for Hot Melt Extrusion and Milling of…
HARKE Povidone Polymers
Povidone-Polymers - Product News Harke Pharma
PVP / Povidone and PVPP / Crospovidone product Portfolio presented at CPhI 2017
Product News_PVP_171016.pdf
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Excipient Database and Online Samples
Excipient Database and Online Samples
The innovative way to access excipients online. One platform to handle all activities from search to delivery of the product samples.
Advantages for Customers / Users…
TAP – Tartaric Acid Pellets
TAP - Tartaric Acid Pellets
TAP are highly spherical starter pellets constist of 100 % Tartaric Acid and act as a pH modifier in extended release formulations of weakly basic drugs. These drugs typically show bad solubility in…
Microcrystalline Cellulose
Sigachi Group, is one of the largest manufacturers of Microcrystalline Cellulose (MCC) in India. The facilities are WHO GMP, HACCP and ISO 9001:2008 certified. The new facility at Special Economic Zone, Dahej, Gujarat has been built…
LUBRIACT – Sodium Stearyl Fumarate
LUBRIACT - Sodium Stearyl Fumarate
LUBRIACT - 50 gram
LUBRIACT Sodium Stearyl Fumarate EP / USP-NF / JPE
is a tablet lubricant for use in traditional and orally disintegrating tablets (ODT), effervescent…