Pharma Excipients

News on Pharma Excipients

Skin Penetration and Permeation Properties of Transcutol® in Complex Formulations

Abstract Percutaneous delivery is explored as alternative pathway for addressing the drawbacks associated with the oral administration of otherwise efficacious drugs. Short of breaching the skin by physical means, the preference goes to formulation strategies that augment passive diffusion across the skin. One such strategy lies in the use of skin…

Excipient Reactivity and Drug Stability in Formulations

This is about the excipient used for achieving sustained release function undergone chemical reaction with the stabilizing agent used for the drug product leading to product quality failure from the desired dissolution behavior. The generic version of Bupropion HCl SR 150 mg, i.e. sustained (12…
Read More...