Twin-screw melt granulation with PEG 8000: Effect of binder particle size and processing temperature on the granule and tablet properties
Twin-screw melt granulation (TSMG) is one of the promising green technological approaches for the manufacturing of solid dosage forms of pharmaceuticals and nutraceuticals. PEG 8000 is one of the most popular TSMG binders. The effect of different low-melting grades of PEG on the TSMG granules’ properties is described in the literature, however, not…