Optimization of meloxicam-phospholipid complex employing QbD based Box-Behnken design for enhanced formulation efficacy
The phospholipids complexation technique is the best solubility enhancement technology, and as a result, many authors have successfully used it to increase the solubility, permeability, and oral bioavailability of numerous drug molecules. The drug belongs to BCS calss II which having poor solubility and higher permeability could have been limited…