Any excipient that can be taken through the mouth can be labelled as an oral excipient.
Pharma Excipients
Oral Excipients
Self-emulsifying micelles as a drug nanocarrier system for itraconazole oral bioavailability…
Abstract
Itraconazole (ITZ) is a renowned antifungal medication, however its therapeutic efficacy is limited by low solubility and oral bioavailability. The current research work attempted to augment the oral bioavailability of ITZ by incorporating into self-emulsifying micelles (SEMCs). To…
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Phospholipids for Advanced OTC Formulations
Phospholipids are amphiphilic, endogenous molecules with excellent biocompatibility and tolerability. Therefore, they are an ideal choice for various “over-the-counter” (OTC) products, including formulations for sensitive tissue such as the ocular surface. Phospholipids can serve as active…
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The Impact of Polymer Mixture Composition on the Properties of Electrospun Membranes for Drug…
Orally dispersible films (ODFs) prepared by an electrospinning are a novel type of pharmaceutical formulation. This dosage form has the potential to be beneficial for small children and the elderly, who can have problems with administration of classical tablets due to the increased risk of choking…
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Microparticles and nanoparticles-based approaches to improve oral treatment of Helicobacter pylori…
Helicobacter pylori is a gram-negative, spiral-shaped, flagellated bacterium that colonizes the stomach of half the world’s population. Helicobacter pylori infection causes pathologies of varying severity. Standard oral therapy fails in 15–20% since the barriers of the oral route decrease the…
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Drug Dissolution in Oral Drug Absorption: Workshop Report
Abstract
The in-person workshop “Drug Dissolution in Oral Drug Absorption” was held on May 23–24, 2023, in Baltimore, MD, USA. The workshop was organized into lectures and breakout sessions. Three common topics that were re-visited by various lecturers were amorphous solid dispersions (ASDs),…
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Adult Patients with Difficulty Swallowing Oral Dosage Forms: A Systematic Review of the Quantitative…
Abstract
The aim of this systematic review was to identify and critically appraise the available evidence regarding solid oral dosage forms (SODFs), e.g., tablets, and challenges regarding the oral administration of medicine to inpatients in a variety of healthcare settings such as (1) hospitals,…
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Enhanced oral delivery of hesperidin-loaded sulfobutylether-β-cyclodextrin/chitosan nanoparticles…
Abstract
Hesperidin (Hsd), a bioactive phytomedicine, experienced an antidiabetic activity versus both Type 1 and Type 2 Diabetes mellitus. However, its intrinsic poor solubility and bioavailability is a key challenging obstacle reflecting its oral delivery. From such perspective, the purpose of…
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Overcoming Challenges of Taste Masking
In a 2003 survey conducted by the American Association of Pediatrics, unpleasant taste was identified as the most significant barrier to completing treatment in pediatrics.
Drug taste masking is extremely relevant to improve patient convenience and compliance. It's currently a relevant…
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Neusilin Redefining Silica´s Potential in Solid Oral Dosage Forms
Neusilin
WHAT IS IT?
Neusilin® UFL2 is an ultra fine powder of magnesium aluminometasilicate and is widely accepted as a problem solving excipient for oral solid dosage forms.
Make harder tablets and protect it from humidity by adding 0.5-5% Neusilin® UFL2 to a lactose or mannitol…
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Formulation and in vitro evaluation of pramipexole orally disintegrating tablets for pediatric…
Abstract
In this study, orally disintegrating tablets (ODT) of pramipexole dihydrochloride monohydrate (PPX) was developed with direct compression method by using ready-to-use excipients Parteck® ODT, Pharmaburst® 500, Ludiflash®, F Melt®, and Prosolv® Easytab SP for pediatric restless leg syndrome…
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