Any excipient that can be taken through the mouth can be labelled as an oral excipient.
Pharma Excipients
Oral Excipients
Solid implantable devices for sustained drug delivery
Implantable drug delivery systems (IDDS) are an attractive alternative to conventional drug administration routes. Oral and injectable drug administration are the most common routes for drug delivery providing peaks of drug concentrations in blood after administration followed by concentration decay…
Read More...
Read More...
Polyvinyl alcohol: Revival of a long lost polymer
Introduction
With target-oriented drug discovery and an increasing focus on specialized medicines, the manufacturing of final drug products is becoming more and more complex. The processing and formulation of active pharmaceutical ingredients (APIs) designed with a specific target and functionality…
Read More...
Read More...
Pharmaceutical evaluation of Levofloxacin orally disintegrating tablet formulation using low…
We evaluated the pharmaceutical properties of levofloxacin (LV) in the form of an orally disintegrating tablet (LVODT) to find a new usefulness of low frequency (LF) Raman spectroscopy. LVODT contained dispersed granules with diameters in the order of several hundred micrometers, which were composed…
Read More...
Read More...
Better performance with Pharma MMC – by Disruptive Pharma
We Can Help
Better performance with Pharma MMC amorphous drug formulations offerings
Give existing products extended life and improved performance.
Facilitate novel drug development with one formulation from pre-clinical, though clinical and to commercial stage.…
Read More...
Read More...
In vitro-in vivo relationship for amorphous solid dispersions using a double membrane…
The use of amorphous solid dispersions (ASDs) is one commonly applied formulation strategy to improve the oral bioavailability of poorly water-soluble drugs by overcoming dissolution rate and/or solubility limitations. While bioavailability enhancement of ASDs is well documented, it has often been a…
Read More...
Read More...
Oral insulin delivery: Barriers, strategies, and formulation approaches: A comprehensive review
Diabetes Mellitus is characterized by a hyperglycemic condition which can either be caused by the destruction of the beta cells or by the resistance developed against insulin in the cells. Insulin is a peptide hormone that regulates the metabolism of carbohydrates, proteins, and fats. Type 1…
Read More...
Read More...
Thiolated polymers: An overview of mucoadhesive properties and their potential in drug delivery via…
Abstract
Thiolated polymers, or thiomers, are a class of polymers that exhibit unique mucoadhesive properties, allowing them to form strong covalent bonds with cysteine-rich subdomains of mucus glycoproteins. This property makes them ideal for developing drug delivery systems (DDSs) for various dry…
Read More...
Read More...
Gin & tonic – the first bittersweet antimalarial
During the 1700s, antimalarial properties of quinine were first unleashed. British soldiers stationed in India began drinking tonic water to prevent and combat the disease. However, quinine has a pronounced bitter taste; in the 1800s, gin was added to make the tonic more palatable. Later, lemon and…
Read More...
Read More...
Layer by layer self-assembly for coating a nanosuspension to modify drug release and stability for…
Layer-by-layer (LbL) modification is an effective way to tune the properties of particles. However, the traditional LbL process involves repeated washing steps which are not compatible with nanoparticles with a partial solubility. In this work, we demonstrate the use of a titration method for…
Read More...
Read More...
Use of surfactant-based amorphous solid dispersions for BDDCS class II drugs to enhance oral…
This paper aimed to improve in vitro dissolution/solubility as well as inhibit intestinal metabolism and thus enhance oral bioavailability for a BDDCS class II drug by constructing surfactant-based amorphous solid dispersions using resveratrol (RES) as a model drug. After preliminary screening of…
Read More...
Read More...