Any excipient that can be taken through the mouth can be labelled as an oral excipient.
Pharma Excipients
Oral Excipients
Long-acting transdermal drug delivery formulations: Current developments and innovative…
Transdermal administration remains an active research and development area as an alternative route for long-acting drug delivery. It avoids major drawbacks of conventional oral (gastrointestinal side effects, low drug bioavailability, and need for multiple dosing) or parenteral routes (invasiveness,…
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An overview of the methods used to increase the dissolution rate of meloxicam for oral…
Abstract
Oral administration of a drug substance has become one of the most important drug delivery routes. In chronic diseases such as rheumatoid arthritis or osteoarthritis, oral forms of drugs are preferred, not only by patients but also by doctors. Meloxicam (MLX) is pharmacologically…
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Novel Patient-Friendly Orodispersible Formulation of Ivermectin is Associated With Enhanced…
Abstract
Ivermectin has been used since the 1980s as an anthelmintic and antiectoparasite agent worldwide. Currently, the only available oral formulation is tablets designed for adult patients. A patient-friendly orodispersible tablet formulation designed for pediatric use (CHILD-IVITAB) has been…
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Self Emulsifying Delivery System of Cissus quadrangularis: Evidence of Enhanced Efficacy and…
Treatment therapies used to manage osteoporosis are associated with severe side effects. So worldwide herbs are widely studied to develop alternative safe & effective treatments. Cissus quadrangularis (CQ) has a significant role in bone health and fracture healing. It is documented that its…
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Development of Oral Tablets of Nebivolol with Improved Dissolution Properties, Based on Its…
Abstract
New oral tablets of nebivolol have been developed aiming to improve, by cyclodextrin (CD) complexation, its low solubility/dissolution properties—the main reason behind its poor/variable oral bioavailability. Phase-solubility studies, performed using βCD and highly-soluble βCD-derivatives,…
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Verapamil-Loaded Cubosomes for Enhancing Intranasal Drug Delivery: Development, Characterization, Ex…
Abstract
Verapamil hydrochloride (VRP), an antihypertensive calcium channel blocker drug has limited bioavailability and short half-life when taken orally. The present study was aimed at developing cubosomes containing VRP for enhancing its bioavailability and targeting to brain for cluster…
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Comparative Life Cycle Assessment and Pharmaceutical Validations of Directly Compressed versus…
Selective laser sintering (SLS)-mediated additive manufacturing (AM) technology is increasingly being used for manufacturing pharmaceutical solid oral dosage forms (SODFs) due to its advantages over other AM and conventional manufacturing (CM) methods. Direct compression (DC) has a competitive edge…
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Oral Delivery of Liraglutide-Loaded Zein/Eudragit-Chitosan Nanoparticles Provides Pharmacokinetic…
Abstract
Liraglutide (LIRA) is a glucagon-like peptide-1 (GLP-1) receptor agonist renowned for its efficacy in treating type 2 diabetes mellitus (T2DM) and is typically administered via subcutaneous injections. Oral delivery, although more desirable for being painless and potentially enhancing…
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Risperidone/cyclodextrin inclusion complex electrospun nanofibers for fast-disintegrating…
In this paper, the inclusion complexes (ICs) of hydroxypropyl-beta-cyclodextrin (HPβCD) and risperidone were electrospun into nanofibrous film for potential fast-disintegrating drug delivery system. Risperidone is used to treat bipolar disorder, schizophrenia, and mood swings from autism. However,…
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L-HPC – Multifunctional excipient for oral solid dose by Shin-Etsu
L-HPC (low-substituted hydroxypropyl cellulose NF, JP, EP) was developed by Shin-Etsu and first approved in 1977 as a disintegrant for tablets in Japan. New grades were developed during the last years in order to cover the needs for our customer having best solutions for individual applications.…
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