Any excipient that can be taken through the mouth can be labelled as an oral excipient.
Pharma Excipients
Oral Excipients
F-MELT: The Cost-Effective Solution For Producing High-Quality Orally Disintegrating Tablets (ODTs)
See the sixth issue of Fuji Chemical Industries Technical Newsletter:
Directly compressible excipient system for fast-Disintegrating oral tablets*,
F-MELT® formulations are designed with a focus on three important characteristics of ODTs: tablet hardness, mouthfeel, and acceptable oral…
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Hyaluronic acid modified oral drug delivery system with mucoadhesiveness and macrophage-targeting…
Based on the biocompatibility and macrophage targeting of natural polysaccharides, combined with the physiological and pathological characteristics of the gastrointestinal tract and colonic mucosa of ulcerative colitis (UC), we prepare dexamethasone (Dex)-loaded oral colon-targeted nano-in-micro…
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A High Throughput Approach of Selecting Excipients for Solubility Enhancement of BCS Class II Active…
Scientists have been faced with the challenge of selecting the right solubilizing excipients for solubility enhancement of poorly water-soluble active pharmaceutical ingredients for decades. In this investigation, the purpose was to ease some of those challenges by developing a first-intent matrix…
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Formulation and in vitro Evaluation of Taste-Masked Orodispersible Tablets of Levocetirizine…
Abstract
The main aim was to formulate and evaluate and optimize taste- masked orodispersible tablets of Levocetirizine Dihydrochloride, a drug used in Allergic Rhinitis was prepared by direct compression method. The study involved different excipients which were used for the formulation and tested…
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Development, QbD based optimization and in vitro characterization of Diacerein loaded nanostructured…
Abstract
Objective
DCN is a chondro-protective agent which displays inadequate oral bioavailability along with gastrointestinal side effects. It is a choice of drug for treatment of osteoarthritis. Therefore, the objective of this study was to develop and optimize DCN loaded nanostructured lipid…
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Oral lyophilizates obtained using aggressive drying conditions: Effect of excipients
Orodispersible drug formulations are a current trend in the pharmaceutical industry, mostly intended for pediatric and geriatric patients. Oral lyophilizates are solid forms, intended either to be placed in the mouth or to be dispersed (or dissolved) in water before administration. The correct…
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Meeting Challenges of Pediatric Drug Delivery: The Potential of Orally Fast Disintegrating Tablets…
A majority of therapeutics are not available as suitable dosage forms for administration to pediatric patients. The first part of this review provides an overview of clinical and technological challenges and opportunities in the development of child-friendly dosage forms such as taste masking,…
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Solubility improvement of curcumin by crystallization inhibition from polymeric surfactants in…
To improve the solubility and maintain the amorphous state of BCS Ⅳ drug by preparing surfactant solid dispersions, solid dispersions of curcumin (CUR) with TPGS and HPMC were prepared by solvent method. The synthesized solid dispersions were characterized by scanning electron microscopy, powder…
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Preparation, Characterization and Evaluation of Flavonolignan Silymarin Effervescent Floating Matrix…
The convenient and highly compliant route for the delivery of active pharmaceutical ingredients is the tablet. A versatile platform of tablets is available for the delivery of therapeutic agents to the gastrointestinal tract. This study aimed to prepare gastro retentive drug delivery floating…
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Development and Optimization of Sildenafil Orodispersible Mini-Tablets (ODMTs) for Treatment of…
The availability of age-appropriate oral dosage forms for pediatric patients has remained a challenge. Orodispersible mini-tablets (ODMTs) are a promising delivery system for pediatric patients. The purpose of this work was the development and optimization of sildenafil ODMTs as a new dosage form…
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