Any excipient that can be taken through the mouth can be labelled as an oral excipient.
Pharma Excipients
Oral Excipients
Insulin-loaded liposomes packaged in alginate hydrogels promote the oral bioavailability of insulin
Compared to subcutaneous injections, oral administration of insulin would be a preferred route of drug administration for diabetic patients. For oral delivery, both liposomes and alginate hydrogels face many challenges, including early burst release of the encapsulated drug and poor intestinal drug…
Read More...
Read More...
Use of high melting point solid vegetable oils in encapsulation processes – ADM White Paper
Use of high melting point solid vegetable oils in encapsulation processes
Introduction to encapsulation
Encapsulation relates to technologies that enable the incorporation of a compound into individualized small
particles. Depending on the process applied, these particles can have…
Read More...
Read More...
Oral self-emulsifying nanoemulsion systems for enhancing dissolution, bioavailability and anticancer…
This research aimed to prepare a camptothecin (CPT) loaded self nano emulsifying drug delivery system (SNEDDS) that would improve the oral therapeutic efficacy of CPT. 32 full factorial design was employed, and the effect of the amount of oil (X1) and surfactant mixture (X2) was systematically…
Read More...
Read More...
Emulsification by vitamin E TPGS or Quillaja extract enhanced absorption of berberine without…
Berberine is widely used for the prevention of cancers and diabetes. However, the absorption rate of berberine is less than 1% in humans. The objective of this research was to determine whether emulsification improves the absorption and affects the metabolism of orally ingested berberine. Twelve…
Read More...
Read More...
MicroceLac® 100 – MEGGLE’s co-processed lactose grades for direct compression
MEGGLE is a pioneer in co-processing technologies that allow simple, robust formulation development and manufacture. Through co-processing, MEGGLE developed highly functional excipients possessing unique qualities for directly compressible immediate and sustained release pharmaceutical solid dosage…
Read More...
Read More...
Oral Disintegrating Tablets – see the solution landscape
Introduction
Oral disintegrating tablets (ODTs) are patient-centric drug delivery systems (for example, for pediatrics, geriatrics, and psychiatric patients with dysphagia) designed to increase patient compliance. ODTs are preferred to classic dosage forms (swallowable / chewable / suckable…
Read More...
Read More...
Milled and Sieved Lactose – MEGGLE’s crystalline alpha-lactose monohydrate grades
MEGGLE is a pioneer in co-processing technologies that allow simple, robust formulation development and manufacture. Through co-processing, MEGGLE developed highly functional excipients possessing unique qualities for directly compressible immediate and sustained release pharmaceutical solid dosage…
Read More...
Read More...
Physical and barrier changes in gastrointestinal mucus induced by the permeation enhancer sodium…
Drug delivery systems (DDS) for oral delivery of peptide drugs contain excipients that facilitate and enhance absorption. However, little knowledge exists on how DDS excipients such as permeation enhancers interact with the gastrointestinal mucus barrier. This study aimed to investigate interactions…
Read More...
Read More...
Inorganic nanoparticles for oral drug delivery: opportunities, barriers, and future perspectives
Abstract
Oral delivery is the preferred route of drug administration due to patient compliance and convenience. Despite this, nanomedicines have so far primarily been developed for the parenteral route. Inorganic nanoparticles hold great promise as theranostics for oral drug delivery. This is…
Read More...
Read More...
Cellactose® 80 – MEGGLE’s co-processed lactose grades for direct compression
MEGGLE is a pioneer in co-processing technologies that allow simple, robust formulation development and manufacture. Through co-processing, MEGGLE developed highly functional excipients possessing unique qualities for directly compressible immediate and sustained release pharmaceutical solid dosage…
Read More...
Read More...